| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
192 genes differentially expressed following the harpagoside-6636 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACAN | aggrecan |
| ACRV1 | acrosomal vesicle protein 1 |
| ACVR1B | activin A receptor, type IB |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADCK4 | aarF domain containing kinase 4 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AREG | amphiregulin |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BEX1 | brain expressed, X-linked 1 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASR | calcium-sensing receptor |
| CDK19 | cyclin-dependent kinase 19 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CNN1 | calponin 1, basic, smooth muscle |
| COL5A1 | collagen, type V, alpha 1 |
| CORO1A | coronin, actin binding protein, 1A |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNPEP | aspartyl aminopeptidase |
| DTNA | dystrobrevin, alpha |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EMID1 | EMI domain containing 1 |
| EPN1 | epsin 1 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM46C | family with sequence similarity 46, member C |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FRMD4B | FERM domain containing 4B |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GJB4 | gap junction protein, beta 4, 30.3kDa |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH4 | G patch domain containing 4 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HAP1 | huntingtin-associated protein 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSF4 | heat shock transcription factor 4 |
| IDS | iduronate 2-sulfatase |
| IL1R2 | interleukin 1 receptor, type II |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| IZUMO4 | IZUMO family member 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDM6B | lysine (K)-specific demethylase 6B |
| KIF1C | kinesin family member 1C |
| KLF12 | Kruppel-like factor 12 |
| KRT38 | keratin 38, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LDLR | low density lipoprotein receptor |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC257152 | uncharacterized LOC257152 |
| MAGEA5 | melanoma antigen family A5 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| METTL7A | methyltransferase like 7A |
| MFAP3L | microfibrillar-associated protein 3-like |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP3 | matrix metallopeptidase 3 |
| MTCP1 | mature T-cell proliferation 1 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NELL2 | NEL-like 2 (chicken) |
| NOTCH4 | notch 4 |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGP | phosphoglycolate phosphatase |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RAD51 | RAD51 recombinase |
| RASAL2 | RAS protein activator like 2 |
| REEP2 | receptor accessory protein 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RGS9 | regulator of G-protein signaling 9 |
| RPL35A | ribosomal protein L35a |
| RPS3A | ribosomal protein S3A |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SMC1A | structural maintenance of chromosomes 1A |
| STK3 | serine/threonine kinase 3 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX13A | testis expressed 13A |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM40 | transmembrane protein 40 |
| TNP2 | transition protein 2 (during histone to protamine replacement) |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| YIPF4 | Yip1 domain family, member 4 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| AGO4 | argonaute RISC catalytic component 4 |
| ALS2CL | ALS2 C-terminal like |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| BTC | betacellulin |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C3 | complement component 3 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN1 | claudin 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRYBA2 | crystallin, beta A2 |
| CSF1R | colony stimulating factor 1 receptor |
| CST1 | cystatin SN |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| EDC3 | enhancer of mRNA decapping 3 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FAM53B | family with sequence similarity 53, member B |
| FBXO40 | F-box protein 40 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FLT4 | fms-related tyrosine kinase 4 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR19 | G protein-coupled receptor 19 |
| GRAMD1C | GRAM domain containing 1C |
| GRB7 | growth factor receptor-bound protein 7 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4D | histone cluster 1, H4d |
| HOXB2 | homeobox B2 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL15RA | interleukin 15 receptor, alpha |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| IQCC | IQ motif containing C |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTC4S | leukotriene C4 synthase |
| MAMLD1 | mastermind-like domain containing 1 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MICALL2 | MICAL-like 2 |
| MYOZ3 | myozenin 3 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NKX3-2 | NK3 homeobox 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| POLL | polymerase (DNA directed), lambda |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PRAME | preferentially expressed antigen in melanoma |
| PRDM14 | PR domain containing 14 |
| PRR16 | proline rich 16 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPGRIP1L | RPGRIP1-like |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SIRT6 | sirtuin 6 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SSBP3 | single stranded DNA binding protein 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYNGR3 | synaptogyrin 3 |
| TBC1D22B | TBC1 domain family, member 22B |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TUBA3C | tubulin, alpha 3c |
| TXK | TXK tyrosine kinase |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR62 | WD repeat domain 62 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF219 | zinc finger protein 219 |
| ZNF268 | zinc finger protein 268 |
| ZNF510 | zinc finger protein 510 |
| ZNF639 | zinc finger protein 639 |
