| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the harpagoside-7355 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADCK2 | aarF domain containing kinase 2 |
| ADM | adrenomedullin |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANGEL2 | angel homolog 2 (Drosophila) |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| AR | androgen receptor |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 |
| B9D2 | B9 protein domain 2 |
| BEX4 | brain expressed, X-linked 4 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA4 | carbonic anhydrase IV |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCDC28B | coiled-coil domain containing 28B |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC14A | cell division cycle 14A |
| CEP85 | centrosomal protein 85kDa |
| CHKB | choline kinase beta |
| COL11A2 | collagen, type XI, alpha 2 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EEA1 | early endosome antigen 1 |
| EXO5 | exonuclease 5 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FADS2 | fatty acid desaturase 2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM214B | family with sequence similarity 214, member B |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GOLGA2 | golgin A2 |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HFE | hemochromatosis |
| HNMT | histamine N-methyltransferase |
| HOMER3 | homer scaffolding protein 3 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGB4 | integrin, beta 4 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOC257152 | uncharacterized LOC257152 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MIIP | migration and invasion inhibitory protein |
| MPDZ | multiple PDZ domain protein |
| NADK | NAD kinase |
| NCOA2 | nuclear receptor coactivator 2 |
| NUP214 | nucleoporin 214kDa |
| NUP88 | nucleoporin 88kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLIN2 | perilipin 2 |
| PLXNA3 | plexin A3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RLN1 | relaxin 1 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SSPN | sarcospan |
| ST20 | suppressor of tumorigenicity 20 |
| SYNJ2 | synaptojanin 2 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBC1D31 | TBC1 domain family, member 31 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TOR1AIP1 | torsin A interacting protein 1 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WAS | Wiskott-Aldrich syndrome |
| XDH | xanthine dehydrogenase |
| ZNF510 | zinc finger protein 510 |
| ZNF532 | zinc finger protein 532 |
| ZNF609 | zinc finger protein 609 |
| ZNF668 | zinc finger protein 668 |
| ZNF821 | zinc finger protein 821 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABHD14A | abhydrolase domain containing 14A |
| ACTL8 | actin-like 8 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| ANKRD36 | ankyrin repeat domain 36 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDON | cell adhesion associated, oncogene regulated |
| CENPO | centromere protein O |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLSTN2 | calsyntenin 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DRD1 | dopamine receptor D1 |
| DYSF | dysferlin |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EPHA2 | EPH receptor A2 |
| ERCC4 | excision repair cross-complementation group 4 |
| EVPL | envoplakin |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBXO31 | F-box protein 31 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPATCH2L | G patch domain containing 2-like |
| GSTA4 | glutathione S-transferase alpha 4 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H4F | histone cluster 1, H4f |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KRT15 | keratin 15, type I |
| LHX1 | LIM homeobox 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MATK | megakaryocyte-associated tyrosine kinase |
| MCC | mutated in colorectal cancers |
| MOCS3 | molybdenum cofactor synthesis 3 |
| NKX3-2 | NK3 homeobox 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PC | pyruvate carboxylase |
| PCDHB3 | protocadherin beta 3 |
| PGBD5 | piggyBac transposable element derived 5 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLAT | plasminogen activator, tissue |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SYNC | syncoilin, intermediate filament protein |
| TARP | TCR gamma alternate reading frame protein |
| TBX19 | T-box 19 |
| TCTN1 | tectonic family member 1 |
| TDRD1 | tudor domain containing 1 |
| TESC | tescalcin |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM53 | transmembrane protein 53 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBQLN4 | ubiquilin 4 |
| UPP1 | uridine phosphorylase 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFC | vascular endothelial growth factor C |
| VIM | vimentin |
| WDR76 | WD repeat domain 76 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF141 | zinc finger protein 141 |
| ZNF506 | zinc finger protein 506 |
| ZNF573 | zinc finger protein 573 |
| ZNF606 | zinc finger protein 606 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |