hdac1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description histone deacetylase 1|Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3065)
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Genes

132 genes co-occuring with the biological term hdac1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AR androgen receptor
ATM ATM serine/threonine kinase
AXIN1 axin 1
BANF1 barrier to autointegration factor 1
BANP BTG3 associated nuclear protein
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRMS1 breast cancer metastasis suppressor 1
CAMP cathelicidin antimicrobial peptide
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHD4 chromodomain helicase DNA binding protein 4
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CPT1A carnitine palmitoyltransferase 1A (liver)
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTBP1 C-terminal binding protein 1
CTNNBIP1 catenin, beta interacting protein 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DEFB1 defensin, beta 1
DGCR8 DGCR8 microprocessor complex subunit
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPF2 D4, zinc and double PHD fingers family 2
E2F1 E2F transcription factor 1
E2F3 E2F transcription factor 3
E2F4 E2F transcription factor 4, p107/p130-binding
E2F7 E2F transcription factor 7
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FOXP3 forkhead box P3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GON4L gon-4-like (C. elegans)
GSTP1 glutathione S-transferase pi 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC6 histone deacetylase 6
HDAC7 histone deacetylase 7
HDAC8 histone deacetylase 8
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HP haptoglobin
HR hair growth associated
IFNB1 interferon, beta 1, fibroblast
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INSM1 insulinoma-associated 1
IRF9 interferon regulatory factor 9
JUN jun proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
KDM1A lysine (K)-specific demethylase 1A
KLF5 Kruppel-like factor 5 (intestinal)
MAGEA1 melanoma antigen family A1
MBD1 methyl-CpG binding domain protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIER1 mesoderm induction early response 1, transcriptional regulator
MIR449A microRNA 449a
MIR449B microRNA 449b
MIR520H microRNA 520h
MIR574 microRNA 574
MIR874 microRNA 874
MMP9 matrix metallopeptidase 9
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEUROD1 neuronal differentiation 1
NFE4 nuclear factor, erythroid 4
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
NR4A1 nuclear receptor subfamily 4, group A, member 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLAU plasminogen activator, urokinase
PML promyelocytic leukemia
PPARD peroxisome proliferator-activated receptor delta
PRB2 proline-rich protein BstNI subfamily 2
RB1 retinoblastoma 1
RCOR1 REST corepressor 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFC1 replication factor C (activator 1) 1, 145kDa
RGS10 regulator of G-protein signaling 10
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RUNX3 runt-related transcription factor 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SAP18 Sin3A-associated protein, 18kDa
SAP30 Sin3A-associated protein, 30kDa
SENP1 SUMO1/sentrin specific peptidase 1
SIN3A SIN3 transcription regulator family member A
SIN3B SIN3 transcription regulator family member B
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNAI2 snail family zinc finger 2
SP1 Sp1 transcription factor
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TNF tumor necrosis factor
TNXB tenascin XB
TP53 tumor protein p53
TRIM28 tripartite motif containing 28
TWIST1 twist family bHLH transcription factor 1
UBTF upstream binding transcription factor, RNA polymerase I
UHRF1 ubiquitin-like with PHD and ring finger domains 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
WHSC1 Wolf-Hirschhorn syndrome candidate 1
YY1 YY1 transcription factor
ZMYM2 zinc finger, MYM-type 2
ZNF148 zinc finger protein 148
ZNF395 zinc finger protein 395