hdac2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description histone deacetylase 2|This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] (NCBI Entrez Gene Database, 3066)
Similar Terms
Downloads & Tools

Genes

61 genes co-occuring with the biological term hdac2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APAF1 apoptotic peptidase activating factor 1
ARG2 arginase 2
ATM ATM serine/threonine kinase
AXIN1 axin 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CBX7 chromobox homolog 7
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIITA class II, major histocompatibility complex, transactivator
CLDN1 claudin 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
DEC1 deleted in esophageal cancer 1
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
ESR1 estrogen receptor 1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDAC8 histone deacetylase 8
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFNL3 interferon, lambda 3
IL17A interleukin 17A
IRF9 interferon regulatory factor 9
KAT2B K(lysine) acetyltransferase 2B
KDM3A lysine (K)-specific demethylase 3A
MIR145 microRNA 145
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTA1 metastasis associated 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
NFE2L2 nuclear factor, erythroid 2-like 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
PADI4 peptidyl arginine deiminase, type IV
PELP1 proline, glutamate and leucine rich protein 1
PGR progesterone receptor
POMC proopiomelanocortin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SIN3A SIN3 transcription regulator family member A
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNAI1 snail family zinc finger 1
SP3 Sp3 transcription factor
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TLR4 toll-like receptor 4
TP53 tumor protein p53
TP63 tumor protein p63
TXNL1 thioredoxin-like 1