hdac5 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description histone deacetylase 5|Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10014)
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Genes

23 genes co-occuring with the biological term hdac5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CAMK2D calcium/calmodulin-dependent protein kinase II delta
FGF2 fibroblast growth factor 2 (basic)
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IFNL3 interferon, lambda 3
KLF2 Kruppel-like factor 2
MEF2A myocyte enhancer factor 2A
MIR2861 microRNA 2861
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NOS3 nitric oxide synthase 3 (endothelial cell)
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
SIX1 SIX homeobox 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLIT2 slit homolog 2 (Drosophila)
TWIST1 twist family bHLH transcription factor 1