healthy oldest-old Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group aging (Genetic Association Database)
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Genes

24 genes associated with the disease healthy oldest-old in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
APOB apolipoprotein B
ASCC1 activating signal cointegrator 1 complex subunit 1
BECN1 beclin 1, autophagy related
CDKN2A cyclin-dependent kinase inhibitor 2A
CRYAB crystallin, alpha B
DLL1 delta-like 1 (Drosophila)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
HSPB2 heat shock 27kDa protein 2
IGF1R insulin-like growth factor 1 receptor
ING1 inhibitor of growth family, member 1
KL klotho
LMNA lamin A/C
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NOTCH1 notch 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
SIRT1 sirtuin 1
SIRT3 sirtuin 3
TP53 tumor protein p53
TRDMT1 tRNA aspartic acid methyltransferase 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
ZMPSTE24 zinc metallopeptidase STE24