| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the hecogenin-3457 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| AJAP1 | adherens junctions associated protein 1 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOE | apolipoprotein E |
| APOM | apolipoprotein M |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARL3 | ADP-ribosylation factor-like 3 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BMP1 | bone morphogenetic protein 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CD82 | CD82 molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CLTC | clathrin, heavy chain (Hc) |
| DAGLA | diacylglycerol lipase, alpha |
| DIO2 | deiodinase, iodothyronine, type II |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPOR | erythropoietin receptor |
| EXOC7 | exocyst complex component 7 |
| FZD1 | frizzled class receptor 1 |
| G6PC3 | glucose 6 phosphatase, catalytic, 3 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GATA4 | GATA binding protein 4 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPSM3 | G-protein signaling modulator 3 |
| GSTM5 | glutathione S-transferase mu 5 |
| HDAC6 | histone deacetylase 6 |
| HFE | hemochromatosis |
| HIST1H4F | histone cluster 1, H4f |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INADL | InaD-like (Drosophila) |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQCC | IQ motif containing C |
| JAG2 | jagged 2 |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KIAA0930 | KIAA0930 |
| KIF1C | kinesin family member 1C |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MED18 | mediator complex subunit 18 |
| MEFV | Mediterranean fever |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MST1 | macrophage stimulating 1 |
| NGLY1 | N-glycanase 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| OSBP2 | oxysterol binding protein 2 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PER1 | period circadian clock 1 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLIN2 | perilipin 2 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POU3F4 | POU class 3 homeobox 4 |
| PRR4 | proline rich 4 (lacrimal) |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBM19 | RNA binding motif protein 19 |
| REEP1 | receptor accessory protein 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RNF122 | ring finger protein 122 |
| RNF126 | ring finger protein 126 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SCAI | suppressor of cancer cell invasion |
| SCAMP1 | secretory carrier membrane protein 1 |
| SDC2 | syndecan 2 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SMTN | smoothelin |
| SNW1 | SNW domain containing 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STON1 | stonin 1 |
| TMEM212 | transmembrane protein 212 |
| TRIM29 | tripartite motif containing 29 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| YY2 | YY2 transcription factor |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACTN4 | actinin, alpha 4 |
| AFF4 | AF4/FMR2 family, member 4 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARRB1 | arrestin, beta 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BCORL1 | BCL6 corepressor-like 1 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CAPN15 | calpain 15 |
| CASD1 | CAS1 domain containing 1 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC109B | coiled-coil domain containing 109B |
| CCDC85C | coiled-coil domain containing 85C |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEP170B | centrosomal protein 170B |
| CEP97 | centrosomal protein 97kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CORT | cortistatin |
| COTL1 | coactosin-like F-actin binding protein 1 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP5 | dual specificity phosphatase 5 |
| FAM53B | family with sequence similarity 53, member B |
| FBRS | fibrosin |
| FGGY | FGGY carbohydrate kinase domain containing |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GPR87 | G protein-coupled receptor 87 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H4J | histone cluster 1, H4j |
| ICK | intestinal cell (MAK-like) kinase |
| IFT81 | intraflagellar transport 81 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IPO8 | importin 8 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0430 | KIAA0430 |
| KIAA0556 | KIAA0556 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMBR1L | limb development membrane protein 1-like |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL21B | methyltransferase like 21B |
| MMP9 | matrix metallopeptidase 9 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NBEAL2 | neurobeachin-like 2 |
| NEK11 | NIMA-related kinase 11 |
| OLFML3 | olfactomedin-like 3 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCBP4 | poly(rC) binding protein 4 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PRSS16 | protease, serine, 16 (thymus) |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RNF121 | ring finger protein 121 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIRT6 | sirtuin 6 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPATA2L | spermatogenesis associated 2-like |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUGP1 | SURP and G patch domain containing 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TBC1D19 | TBC1 domain family, member 19 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM180 | transmembrane protein 180 |
| TMEM183A | transmembrane protein 183A |
| TMEM62 | transmembrane protein 62 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM25 | tripartite motif containing 25 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| WDR33 | WD repeat domain 33 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF35 | zinc finger protein 35 |
| ZNF516 | zinc finger protein 516 |
| ZNF747 | zinc finger protein 747 |
| ZNF8 | zinc finger protein 8 |
