heliotrine-3615 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the heliotrine-3615 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM8 ADAM metallopeptidase domain 8
AMPH amphiphysin
BIN1 bridging integrator 1
BMP8B bone morphogenetic protein 8b
BTN3A1 butyrophilin, subfamily 3, member A1
C11ORF16 chromosome 11 open reading frame 16
CD200 CD200 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CLCF1 cardiotrophin-like cytokine factor 1
CNN3 calponin 3, acidic
COL14A1 collagen, type XIV, alpha 1
COL6A2 collagen, type VI, alpha 2
CYSLTR2 cysteinyl leukotriene receptor 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK2 death-associated protein kinase 2
DCTN2 dynactin 2 (p50)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DOC2B double C2-like domains, beta
DRD5 dopamine receptor D5
EFR3B EFR3 homolog B (S. cerevisiae)
EHD2 EH-domain containing 2
ELMO1 engulfment and cell motility 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ESRRG estrogen-related receptor gamma
FAM49B family with sequence similarity 49, member B
FGF6 fibroblast growth factor 6
FLJ11710 uncharacterized protein FLJ11710
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GM2A GM2 ganglioside activator
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSPT2 G1 to S phase transition 2
HBS1L HBS1-like translational GTPase
HHIPL2 HHIP-like 2
HPGDS hematopoietic prostaglandin D synthase
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDM8 lysine (K)-specific demethylase 8
KIFC3 kinesin family member C3
KLHL1 kelch-like family member 1
KRT37 keratin 37, type I
LMAN1L lectin, mannose-binding, 1 like
LOC157562 uncharacterized LOC157562
LOC399491
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBD2 methyl-CpG binding domain protein 2
MCF2L MCF.2 cell line derived transforming sequence-like
MKL1 megakaryoblastic leukemia (translocation) 1
MOXD1 monooxygenase, DBH-like 1
MRC2 mannose receptor, C type 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEUROD1 neuronal differentiation 1
NEUROD4 neuronal differentiation 4
NPR3 natriuretic peptide receptor 3
OR1E1 olfactory receptor, family 1, subfamily E, member 1
OSBPL10 oxysterol binding protein-like 10
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCNX pecanex homolog (Drosophila)
PGAP3 post-GPI attachment to proteins 3
POU5F1B POU class 5 homeobox 1B
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRODH2 proline dehydrogenase (oxidase) 2
PRR34 proline rich 34
PTCH1 patched 1
RAB6B RAB6B, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RUNX1 runt-related transcription factor 1
S100A1 S100 calcium binding protein A1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SRPK2 SRSF protein kinase 2
SRRT serrate, RNA effector molecule
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYN3 synapsin III
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBRG4 transforming growth factor beta regulator 4
TBX21 T-box 21
TENM4 teneurin transmembrane protein 4
TERT telomerase reverse transcriptase
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM63A transmembrane protein 63A
TONSL tonsoku-like, DNA repair protein
UTRN utrophin
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR62 WD repeat domain 62
WNT2 wingless-type MMTV integration site family member 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF304 zinc finger protein 304
ZNF639 zinc finger protein 639
ZNF79 zinc finger protein 79
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
AFAP1 actin filament associated protein 1
AIRE autoimmune regulator
APOD apolipoprotein D
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
BCO1 beta-carotene oxygenase 1
BMP10 bone morphogenetic protein 10
C11ORF21 chromosome 11 open reading frame 21
C2ORF27A chromosome 2 open reading frame 27A
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCP110 centriolar coiled coil protein 110kDa
CD3D CD3d molecule, delta (CD3-TCR complex)
CD53 CD53 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CENPO centromere protein O
CFAP70 cilia and flagella associated protein 70
CHM choroideremia (Rab escort protein 1)
CLGN calmegin
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
CUL9 cullin 9
CUZD1 CUB and zona pellucida-like domains 1
DCAF13 DDB1 and CUL4 associated factor 13
DEAF1 DEAF1 transcription factor
DIO1 deiodinase, iodothyronine, type I
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DOK2 docking protein 2, 56kDa
DUSP9 dual specificity phosphatase 9
DYSF dysferlin
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FAM198B family with sequence similarity 198, member B
FBXO31 F-box protein 31
FKBP5 FK506 binding protein 5
FSD1 fibronectin type III and SPRY domain containing 1
GAMT guanidinoacetate N-methyltransferase
GFI1 growth factor independent 1 transcription repressor
GPATCH3 G patch domain containing 3
HIST1H1E histone cluster 1, H1e
HIST1H4A histone cluster 1, H4a
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC5 homeobox C5
IL12RB1 interleukin 12 receptor, beta 1
ITM2C integral membrane protein 2C
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT9 keratin 9, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MEFV Mediterranean fever
MOB3B MOB kinase activator 3B
MON1B MON1 secretory trafficking family member B
NIPAL2 NIPA-like domain containing 2
NPY4R neuropeptide Y receptor Y4
NT5DC3 5'-nucleotidase domain containing 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OVOL1 ovo-like zinc finger 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRF1 perforin 1 (pore forming protein)
PRPH peripherin
RCAN3 RCAN family member 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS2 regulator of G-protein signaling 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF208 ring finger protein 208
RPL13P5 ribosomal protein L13 pseudogene 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIX1 SIX homeobox 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLIT2 slit homolog 2 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
ST5 suppression of tumorigenicity 5
STAG3 stromal antigen 3
STK25 serine/threonine kinase 25
TBC1D19 TBC1 domain family, member 19
TEX40 testis expressed 40
TGFBR3 transforming growth factor, beta receptor III
TMEM242 transmembrane protein 242
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
UPP1 uridine phosphorylase 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF329 zinc finger protein 329
ZNF350 zinc finger protein 350
ZNF606 zinc finger protein 606
ZSCAN2 zinc finger and SCAN domain containing 2
ZSCAN31 zinc finger and SCAN domain containing 31