| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the heliotrine-4277 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ADRA1A | adrenoceptor alpha 1A |
| ANGPTL2 | angiopoietin-like 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| BMP5 | bone morphogenetic protein 5 |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CASZ1 | castor zinc finger 1 |
| CD248 | CD248 molecule, endosialin |
| CD80 | CD80 molecule |
| CD86 | CD86 molecule |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| CYTH3 | cytohesin 3 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNASE1 | deoxyribonuclease I |
| EFCAB6 | EF-hand calcium binding domain 6 |
| ELAC2 | elaC ribonuclease Z 2 |
| ELN | elastin |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ESR1 | estrogen receptor 1 |
| ESR2 | estrogen receptor 2 (ER beta) |
| FAP | fibroblast activation protein, alpha |
| GALR3 | galanin receptor 3 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXD1 | homeobox D1 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFT140 | intraflagellar transport 140 |
| IL2 | interleukin 2 |
| IRF4 | interferon regulatory factor 4 |
| IRX4 | iroquois homeobox 4 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KDM5B | lysine (K)-specific demethylase 5B |
| KHK | ketohexokinase (fructokinase) |
| KLHL35 | kelch-like family member 35 |
| KLK13 | kallikrein-related peptidase 13 |
| KLK7 | kallikrein-related peptidase 7 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| KRT85 | keratin 85, type II |
| LAD1 | ladinin 1 |
| LCAT | lecithin-cholesterol acyltransferase |
| LRP2BP | LRP2 binding protein |
| LTC4S | leukotriene C4 synthase |
| MAP2 | microtubule-associated protein 2 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MEGF6 | multiple EGF-like-domains 6 |
| MSX2 | msh homeobox 2 |
| NF1 | neurofibromin 1 |
| OCA2 | oculocutaneous albinism II |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| P2RX6 | purinergic receptor P2X, ligand gated ion channel, 6 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCDH12 | protocadherin 12 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PKP3 | plakophilin 3 |
| PLSCR2 | phospholipid scramblase 2 |
| PNPLA2 | patatin-like phospholipase domain containing 2 |
| POU2F3 | POU class 2 homeobox 3 |
| PQLC2 | PQ loop repeat containing 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKCQ | protein kinase C, theta |
| RAB40C | RAB40C, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RRAGD | Ras-related GTP binding D |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SNX1 | sorting nexin 1 |
| SPEF1 | sperm flagellar 1 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TRIM3 | tripartite motif containing 3 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBE3A | ubiquitin protein ligase E3A |
| VPREB1 | pre-B lymphocyte 1 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| VTN | vitronectin |
| ZPBP | zona pellucida binding protein |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD8 | abhydrolase domain containing 8 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ASTN2 | astrotactin 2 |
| AXIN1 | axin 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| BOLA1 | bolA family member 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA9 | carbonic anhydrase IX |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD82 | CD82 molecule |
| CES3 | carboxylesterase 3 |
| COL21A1 | collagen, type XXI, alpha 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DEAF1 | DEAF1 transcription factor |
| DENND4A | DENN/MADD domain containing 4A |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| FAM204A | family with sequence similarity 204, member A |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GK3P | glycerol kinase 3 pseudogene |
| HDAC5 | histone deacetylase 5 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOMER2 | homer scaffolding protein 2 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IFNA17 | interferon, alpha 17 |
| IL11RA | interleukin 11 receptor, alpha |
| IL7 | interleukin 7 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0319L | KIAA0319-like |
| KLHL36 | kelch-like family member 36 |
| LMNB2 | lamin B2 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NABP2 | nucleic acid binding protein 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NFS1 | NFS1 cysteine desulfurase |
| NID2 | nidogen 2 (osteonidogen) |
| NPR3 | natriuretic peptide receptor 3 |
| OLFML3 | olfactomedin-like 3 |
| PALM | paralemmin |
| PARPBP | PARP1 binding protein |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDZD2 | PDZ domain containing 2 |
| PDZK1 | PDZ domain containing 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLXNB3 | plexin B3 |
| POLL | polymerase (DNA directed), lambda |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCG5 | secretogranin V |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SPIDR | scaffolding protein involved in DNA repair |
| TCTN1 | tectonic family member 1 |
| TEP1 | telomerase-associated protein 1 |
| TEX30 | testis expressed 30 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TWISTNB | TWIST neighbor |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| UNC13B | unc-13 homolog B (C. elegans) |
| USP18 | ubiquitin specific peptidase 18 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| XYLT2 | xylosyltransferase II |
| ZNF10 | zinc finger protein 10 |
| ZNF112 | zinc finger protein 112 |
| ZNF215 | zinc finger protein 215 |
| ZNF230 | zinc finger protein 230 |
| ZNF286A | zinc finger protein 286A |
| ZNF33B | zinc finger protein 33B |