| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the helveticoside-2192 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AREG | amphiregulin |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTG2 | BTG family, member 2 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C3AR1 | complement component 3a receptor 1 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CD83 | CD83 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLEC4A | C-type lectin domain family 4, member A |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CREM | cAMP responsive element modulator |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| EED | embryonic ectoderm development |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ETNK1 | ethanolamine kinase 1 |
| FCAR | Fc fragment of IgA receptor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| G0S2 | G0/G1 switch 2 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GOLT1B | golgi transport 1B |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-F | major histocompatibility complex, class I, F |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IL1A | interleukin 1, alpha |
| IL1B | interleukin 1, beta |
| IL1RN | interleukin 1 receptor antagonist |
| IL24 | interleukin 24 |
| IL6ST | interleukin 6 signal transducer |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| ITGA8 | integrin, alpha 8 |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLHL24 | kelch-like family member 24 |
| KRT10 | keratin 10, type I |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LDLR | low density lipoprotein receptor |
| LIF | leukemia inhibitory factor |
| LINS | lines homolog (Drosophila) |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MSR1 | macrophage scavenger receptor 1 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NFYA | nuclear transcription factor Y, alpha |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUP188 | nucleoporin 188kDa |
| NUPL1 | nucleoporin like 1 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLCB4 | phospholipase C, beta 4 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM10 | PR domain containing 10 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTX3 | pentraxin 3, long |
| RBM15 | RNA binding motif protein 15 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLN | sarcolipin |
| SMC4 | structural maintenance of chromosomes 4 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SPRR2B | small proline-rich protein 2B |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| STK17B | serine/threonine kinase 17b |
| THBS1 | thrombospondin 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TUBB3 | tubulin, beta 3 class III |
| TXNIP | thioredoxin interacting protein |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZFAND6 | zinc finger, AN1-type domain 6 |
| ZNF143 | zinc finger protein 143 |
| ZNF335 | zinc finger protein 335 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADM | adrenomedullin |
| ARMC7 | armadillo repeat containing 7 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BBS10 | Bardet-Biedl syndrome 10 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CBR1 | carbonyl reductase 1 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CEL | carboxyl ester lipase |
| COL15A1 | collagen, type XV, alpha 1 |
| CSK | c-src tyrosine kinase |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCF | Fanconi anemia, complementation group F |
| FHL3 | four and a half LIM domains 3 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| JRKL | JRK-like |
| KAT2A | K(lysine) acetyltransferase 2A |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRRC8D | leucine rich repeat containing 8 family, member D |
| LXN | latexin |
| MANSC1 | MANSC domain containing 1 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MINA | MYC induced nuclear antigen |
| MKKS | McKusick-Kaufman syndrome |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MNS1 | meiosis-specific nuclear structural 1 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MUTYH | mutY homolog |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NLRX1 | NLR family member X1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PAAF1 | proteasomal ATPase-associated factor 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PALB2 | partner and localizer of BRCA2 |
| PEX1 | peroxisomal biogenesis factor 1 |
| PEX11B | peroxisomal biogenesis factor 11 beta |
| PEX12 | peroxisomal biogenesis factor 12 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| PRDM13 | PR domain containing 13 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRR3 | proline rich 3 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RFXAP | regulatory factor X-associated protein |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SLC35E3 | solute carrier family 35, member E3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TGM5 | transglutaminase 5 |
| TMEM177 | transmembrane protein 177 |
| TMEM186 | transmembrane protein 186 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog |
| WDR3 | WD repeat domain 3 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF23 | zinc finger protein 23 |
| ZNF248 | zinc finger protein 248 |
| ZNF250 | zinc finger protein 250 |
| ZNF302 | zinc finger protein 302 |
| ZNF32 | zinc finger protein 32 |
| ZNF33B | zinc finger protein 33B |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF395 | zinc finger protein 395 |
| ZNF529 | zinc finger protein 529 |
| ZNF552 | zinc finger protein 552 |
| ZNF623 | zinc finger protein 623 |
| ZNF7 | zinc finger protein 7 |
| ZW10 | zw10 kinetochore protein |
