| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the helveticoside-3770 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADM | adrenomedullin |
| AFF4 | AF4/FMR2 family, member 4 |
| ANGPTL4 | angiopoietin-like 4 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF3 | activating transcription factor 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BDNF | brain-derived neurotrophic factor |
| BTG2 | BTG family, member 2 |
| CCNL1 | cyclin L1 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDKN2AIP | CDKN2A interacting protein |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN1 | claudin 1 |
| CLK1 | CDC-like kinase 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CTGF | connective tissue growth factor |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DLX2 | distal-less homeobox 2 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL2 | FOS-like antigen 2 |
| FRMD4B | FERM domain containing 4B |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GHRHR | growth hormone releasing hormone receptor |
| GPR87 | G protein-coupled receptor 87 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3A | histone cluster 1, H3a |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HIST2H2BE | histone cluster 2, H2be |
| HIST3H2A | histone cluster 3, H2a |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| JUND | jun D proto-oncogene |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL25 | kelch-like family member 25 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAK | male germ cell-associated kinase |
| MYLIP | myosin regulatory light chain interacting protein |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PER2 | period circadian clock 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB30 | RAB30, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RNMT | RNA (guanine-7-) methyltransferase |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SNAI1 | snail family zinc finger 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STC2 | stanniocalcin 2 |
| STX3 | syntaxin 3 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TEX14 | testis expressed 14 |
| TGFB2 | transforming growth factor, beta 2 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOB2 | transducer of ERBB2, 2 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATP10D | ATPase, class V, type 10D |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBR3 | carbonyl reductase 3 |
| CDC7 | cell division cycle 7 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CPT2 | carnitine palmitoyltransferase 2 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DENND2D | DENN/MADD domain containing 2D |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| EFNB1 | ephrin-B1 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FANCF | Fanconi anemia, complementation group F |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FHOD1 | formin homology 2 domain containing 1 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GLMN | glomulin, FKBP associated protein |
| GLT8D1 | glycosyltransferase 8 domain containing 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GOLGA5 | golgin A5 |
| GPR19 | G protein-coupled receptor 19 |
| GRAMD4 | GRAM domain containing 4 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HOXA11 | homeobox A11 |
| HOXC10 | homeobox C10 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| ITGA10 | integrin, alpha 10 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JRKL | JRK-like |
| KIAA1107 | KIAA1107 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGEH1 | melanoma antigen family H1 |
| MAP6D1 | MAP6 domain containing 1 |
| MED31 | mediator complex subunit 31 |
| MKS1 | Meckel syndrome, type 1 |
| MLYCD | malonyl-CoA decarboxylase |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NME5 | NME/NM23 family member 5 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PALMD | palmdelphin |
| PAQR5 | progestin and adipoQ receptor family member V |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PLXNB3 | plexin B3 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| RAB3A | RAB3A, member RAS oncogene family |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPGRIP1L | RPGRIP1-like |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| RWDD2A | RWD domain containing 2A |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SEPHS2 | selenophosphate synthetase 2 |
| SETD6 | SET domain containing 6 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBCCD1 | TBCC domain containing 1 |
| TENM4 | teneurin transmembrane protein 4 |
| TRIM52 | tripartite motif containing 52 |
| TRIM66 | tripartite motif containing 66 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| TTC30A | tetratricopeptide repeat domain 30A |
| WDR25 | WD repeat domain 25 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF140 | zinc finger protein 140 |
| ZNF205 | zinc finger protein 205 |
| ZNF239 | zinc finger protein 239 |
| ZNF32 | zinc finger protein 32 |
| ZNF365 | zinc finger protein 365 |
| ZNF668 | zinc finger protein 668 |
| ZNF76 | zinc finger protein 76 |
| ZNF862 | zinc finger protein 862 |
