helveticoside-3851 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the helveticoside-3851 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AFF4 AF4/FMR2 family, member 4
AMOTL2 angiomotin like 2
ATF3 activating transcription factor 3
AVPI1 arginine vasopressin-induced 1
BCL6 B-cell CLL/lymphoma 6
BTG1 B-cell translocation gene 1, anti-proliferative
CCNT1 cyclin T1
CCNT2 cyclin T2
CGA glycoprotein hormones, alpha polypeptide
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CNOT4 CCR4-NOT transcription complex, subunit 4
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAPK3 death-associated protein kinase 3
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EDRF1 erythroid differentiation regulatory factor 1
EED embryonic ectoderm development
EFNA1 ephrin-A1
EFNB2 ephrin-B2
EGR1 early growth response 1
EPHA2 EPH receptor A2
EWSR1 EWS RNA-binding protein 1
FAM46A family with sequence similarity 46, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HCFC2 host cell factor C2
HIC2 hypermethylated in cancer 2
HOXC13 homeobox C13
HSF2 heat shock transcription factor 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IL6 interleukin 6
IP6K2 inositol hexakisphosphate kinase 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF10 Kruppel-like factor 10
KLF5 Kruppel-like factor 5 (intestinal)
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
KMT2A lysine (K)-specific methyltransferase 2A
LINS lines homolog (Drosophila)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MCL1 myeloid cell leukemia 1
MXD1 MAX dimerization protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OVOL1 ovo-like zinc finger 1
PCDH9 protocadherin 9
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
RARG retinoic acid receptor, gamma
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM5 RNA binding motif protein 5
RGS16 regulator of G-protein signaling 16
RXRB retinoid X receptor, beta
RYBP RING1 and YY1 binding protein
SERTAD3 SERTA domain containing 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SIK1 salt-inducible kinase 1
SKIL SKI-like proto-oncogene
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SRSF5 serine/arginine-rich splicing factor 5
STK17B serine/threonine kinase 17b
STX3 syntaxin 3
SWAP70 SWAP switching B-cell complex 70kDa subunit
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOB2 transducer of ERBB2, 2
TPP1 tripeptidyl peptidase I
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF4 TNF receptor-associated factor 4
TXNIP thioredoxin interacting protein
WAC WW domain containing adaptor with coiled-coil
WASL Wiskott-Aldrich syndrome-like
YTHDC1 YTH domain containing 1
ZBTB43 zinc finger and BTB domain containing 43
ZMYM2 zinc finger, MYM-type 2
ZNF324 zinc finger protein 324
ZNF335 zinc finger protein 335
ZNF654 zinc finger protein 654
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ADAT1 adenosine deaminase, tRNA-specific 1
AHNAK2 AHNAK nucleoprotein 2
ANKRD46 ankyrin repeat domain 46
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASB13 ankyrin repeat and SOCS box containing 13
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ASTN2 astrotactin 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
CAMTA1 calmodulin binding transcription activator 1
CBR3 carbonyl reductase 3
CCDC15 coiled-coil domain containing 15
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CORO2A coronin, actin binding protein, 2A
CSK c-src tyrosine kinase
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAAF2 dynein, axonemal, assembly factor 2
DUS2 dihydrouridine synthase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR3 early growth response 3
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM86B1 family with sequence similarity 86, member B1
FANCF Fanconi anemia, complementation group F
FMO4 flavin containing monooxygenase 4
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GEMIN6 gem (nuclear organelle) associated protein 6
GPALPP1 GPALPP motifs containing 1
GPR19 G protein-coupled receptor 19
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
HPS6 Hermansky-Pudlak syndrome 6
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
INCENP inner centromere protein antigens 135/155kDa
JRKL JRK-like
KIAA0125 KIAA0125
KRCC1 lysine-rich coiled-coil 1
LINC00339 long intergenic non-protein coding RNA 339
LOC100287590 uncharacterized LOC100287590
LOC730101 uncharacterized LOC730101
LRRC61 leucine rich repeat containing 61
MEIS1 Meis homeobox 1
MKKS McKusick-Kaufman syndrome
MKS1 Meckel syndrome, type 1
MORC2 MORC family CW-type zinc finger 2
MTA2 metastasis associated 1 family, member 2
MXD3 MAX dimerization protein 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
PAAF1 proteasomal ATPase-associated factor 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PALB2 partner and localizer of BRCA2
PCF11 PCF11 cleavage and polyadenylation factor subunit
PER3 period circadian clock 3
PEX12 peroxisomal biogenesis factor 12
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PRR3 proline rich 3
PSPH phosphoserine phosphatase
PTCD2 pentatricopeptide repeat domain 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHOBTB1 Rho-related BTB domain containing 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPP40 ribonuclease P/MRP 40kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSAD1 radical S-adenosyl methionine domain containing 1
S100PBP S100P binding protein
SACS sacsin molecular chaperone
SCO2 SCO2 cytochrome c oxidase assembly protein
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOWAHC sosondowah ankyrin repeat domain family member C
STARD7 StAR-related lipid transfer (START) domain containing 7
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBC1D31 TBC1 domain family, member 31
TBCCD1 TBCC domain containing 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THYN1 thymocyte nuclear protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TUBA3C tubulin, alpha 3c
WDR3 WD repeat domain 3
XBP1 X-box binding protein 1
ZBED8 zinc finger, BED-type containing 8
ZBTB24 zinc finger and BTB domain containing 24
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZFP30 ZFP30 zinc finger protein
ZIC1 Zic family member 1
ZNF23 zinc finger protein 23
ZNF239 zinc finger protein 239
ZNF248 zinc finger protein 248
ZNF302 zinc finger protein 302
ZNF623 zinc finger protein 623