| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the helveticoside-4327 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADM | adrenomedullin |
| AFF4 | AF4/FMR2 family, member 4 |
| ANKRD12 | ankyrin repeat domain 12 |
| ARC | activity-regulated cytoskeleton-associated protein |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| ATP13A3 | ATPase type 13A3 |
| BDNF | brain-derived neurotrophic factor |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN1 | claudin 1 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| CYTH3 | cytohesin 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DLX2 | distal-less homeobox 2 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EDN1 | endothelin 1 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRMD4B | FERM domain containing 4B |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPR87 | G protein-coupled receptor 87 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| IL6R | interleukin 6 receptor |
| JUN | jun proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KITLG | KIT ligand |
| KLF4 | Kruppel-like factor 4 (gut) |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCL1 | myeloid cell leukemia 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFAP3 | microfibrillar-associated protein 3 |
| MRPL20 | mitochondrial ribosomal protein L20 |
| NCOA3 | nuclear receptor coactivator 3 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| PLK4 | polo-like kinase 4 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| QKI | QKI, KH domain containing, RNA binding |
| RAB30 | RAB30, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35F5 | solute carrier family 35, member F5 |
| SMAD7 | SMAD family member 7 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| STC2 | stanniocalcin 2 |
| STK17B | serine/threonine kinase 17b |
| STX3 | syntaxin 3 |
| TEX14 | testis expressed 14 |
| TGFB2 | transforming growth factor, beta 2 |
| THBS1 | thrombospondin 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM156 | transmembrane protein 156 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TSC22D1 | TSC22 domain family, member 1 |
| TSC22D2 | TSC22 domain family, member 2 |
| TUFT1 | tuftelin 1 |
| TXNIP | thioredoxin interacting protein |
| WDR33 | WD repeat domain 33 |
| YOD1 | YOD1 deubiquitinase |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZFP36 | ZFP36 ring finger protein |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF24 | zinc finger protein 24 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ASTN2 | astrotactin 2 |
| ATP13A2 | ATPase type 13A2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BRCA1 | breast cancer 1, early onset |
| CAPN15 | calpain 15 |
| CBR3 | carbonyl reductase 3 |
| CBX8 | chromobox homolog 8 |
| CCDC106 | coiled-coil domain containing 106 |
| CCNO | cyclin O |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CUL9 | cullin 9 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EFNB1 | ephrin-B1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPHB6 | EPH receptor B6 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FANCF | Fanconi anemia, complementation group F |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FHOD1 | formin homology 2 domain containing 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JRKL | JRK-like |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAGEH1 | melanoma antigen family H1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP6D1 | MAP6 domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| NABP2 | nucleic acid binding protein 2 |
| NME5 | NME/NM23 family member 5 |
| NOL12 | nucleolar protein 12 |
| NOTCH1 | notch 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POLM | polymerase (DNA directed), mu |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKX | protein kinase, X-linked |
| PTK6 | protein tyrosine kinase 6 |
| RBM15B | RNA binding motif protein 15B |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNPH | syntaphilin |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| TAOK1 | TAO kinase 1 |
| TBC1D16 | TBC1 domain family, member 16 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TLN1 | talin 1 |
| TMEM121 | transmembrane protein 121 |
| TRAIP | TRAF interacting protein |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSC22D4 | TSC22 domain family, member 4 |
| UNKL | unkempt family zinc finger-like |
| USP20 | ubiquitin specific peptidase 20 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF177 | zinc finger protein 177 |
| ZNF239 | zinc finger protein 239 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF76 | zinc finger protein 76 |
