The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. (Gene Ontology, GO_0060218)
10 genes participating in the hematopoietic stem cell differentiation biological process from the curated GO Biological Process Annotations 2025 dataset.
