heme biosynthesis Gene Set

Dataset HumanCyc Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. (Gene Ontology, GO_0006783)
External Link http://humancyc.org/HUMAN/NEW-IMAGE?type=PATHWAY&object=PWY-5920
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Genes

9 proteins participating in the heme biosynthesis pathway from the HumanCyc Pathways dataset.

Symbol Name
ALAD aminolevulinate dehydratase
ALAS1 5'-aminolevulinate synthase 1
ALAS2 5'-aminolevulinate synthase 2
CPOX coproporphyrinogen oxidase
FECH ferrochelatase
HMBS hydroxymethylbilane synthase
PPOX protoporphyrinogen oxidase
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase