heme biosynthetic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. (Gene Ontology, GO_0006783)
External Link http://amigo.geneontology.org/amigo/term/GO:0006783
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Genes

20 genes participating in the heme biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ALAD aminolevulinate dehydratase
ALAS1 5'-aminolevulinate synthase 1
ALAS2 5'-aminolevulinate synthase 2
ATPIF1 ATPase inhibitory factor 1
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPOX coproporphyrinogen oxidase
FECH ferrochelatase
FXN frataxin
HMBS hydroxymethylbilane synthase
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
NFE2L1 nuclear factor, erythroid 2-like 1
PPOX protoporphyrinogen oxidase
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC25A38 solute carrier family 25, member 38
SLC25A39 solute carrier family 25, member 39
TMEM14C transmembrane protein 14C
TSPO translocator protein (18kDa)
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase
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