heme biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. (Gene Ontology, GO_0006783)
External Link http://amigo.geneontology.org/amigo/term/GO:0006783
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Genes

20 genes participating in the heme biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ALAD aminolevulinate dehydratase
ALAS1 5'-aminolevulinate synthase 1
ALAS2 5'-aminolevulinate synthase 2
ATP5IF1 ATP synthase inhibitory factor subunit 1
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPOX coproporphyrinogen oxidase
FECH ferrochelatase
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FXN frataxin
HMBS hydroxymethylbilane synthase
NFE2L1 nuclear factor, erythroid 2-like 1
PGRMC1 progesterone receptor membrane component 1
PPOX protoporphyrinogen oxidase
SLC25A38 solute carrier family 25, member 38
TSPO translocator protein (18kDa)
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase