heme metabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. (Gene Ontology, GO_0042168)
External Link http://amigo.geneontology.org/amigo/term/GO:0042168
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Genes

34 genes participating in the heme metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ALAD aminolevulinate dehydratase
ALAS1 5'-aminolevulinate synthase 1
ALAS2 5'-aminolevulinate synthase 2
AMBP alpha-1-microglobulin/bikunin precursor
ATP5IF1 ATP synthase inhibitory factor subunit 1
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BLVRA biliverdin reductase A
BLVRB biliverdin reductase B
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
CPOX coproporphyrinogen oxidase
FECH ferrochelatase
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FXN frataxin
HMBS hydroxymethylbilane synthase
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HPX hemopexin
NFE2L1 nuclear factor, erythroid 2-like 1
PGRMC1 progesterone receptor membrane component 1
PPOX protoporphyrinogen oxidase
SLC25A38 solute carrier family 25, member 38
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLCO2B1 solute carrier organic anion transporter family, member 2B1
TSPO translocator protein (18kDa)
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UROD uroporphyrinogen decarboxylase
UROS uroporphyrinogen III synthase