hemicholinium-1601 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the hemicholinium-1601 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADAM22 ADAM metallopeptidase domain 22
AGGF1 angiogenic factor with G patch and FHA domains 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASCC1 activating signal cointegrator 1 complex subunit 1
BCAN brevican
BCL6 B-cell CLL/lymphoma 6
C2ORF68 chromosome 2 open reading frame 68
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CALML3 calmodulin-like 3
CANT1 calcium activated nucleotidase 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC64 coiled-coil domain containing 64
CCL23 chemokine (C-C motif) ligand 23
CDCA3 cell division cycle associated 3
CDK12 cyclin-dependent kinase 12
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CEND1 cell cycle exit and neuronal differentiation 1
CIZ1 CDKN1A interacting zinc finger protein 1
CLASRP CLK4-associating serine/arginine rich protein
CLIP1 CAP-GLY domain containing linker protein 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DEDD death effector domain containing
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIO2 deiodinase, iodothyronine, type II
DSCR3 Down syndrome critical region 3
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ELF4 E74-like factor 4 (ets domain transcription factor)
EXOC7 exocyst complex component 7
FASTK Fas-activated serine/threonine kinase
FBP1 fructose-1,6-bisphosphatase 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FHL1 four and a half LIM domains 1
FOXN3 forkhead box N3
GDF9 growth differentiation factor 9
GJD2 gap junction protein, delta 2, 36kDa
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR21 G protein-coupled receptor 21
GRK6 G protein-coupled receptor kinase 6
GSTM5 glutathione S-transferase mu 5
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCFC1 host cell factor C1
HSPB11 heat shock protein family B (small), member 11
HUS1 HUS1 checkpoint homolog (S. pombe)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIFAP3 kinesin-associated protein 3
LINC00574 long intergenic non-protein coding RNA 574
LMF2 lipase maturation factor 2
LPP LIM domain containing preferred translocation partner in lipoma
LRRC37A2 leucine rich repeat containing 37, member A2
MED31 mediator complex subunit 31
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MOB3B MOB kinase activator 3B
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYO1C myosin IC
N4BP1 NEDD4 binding protein 1
NBPF10 neuroblastoma breakpoint family, member 10
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NXF2 nuclear RNA export factor 2
PADI1 peptidyl arginine deiminase, type I
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PEX10 peroxisomal biogenesis factor 10
PLD2 phospholipase D2
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB8B RAB8B, member RAS oncogene family
RAD1 RAD1 checkpoint DNA exonuclease
RECQL5 RecQ protein-like 5
RNF39 ring finger protein 39
RRP1B ribosomal RNA processing 1B
SAFB2 scaffold attachment factor B2
SETD4 SET domain containing 4
SEZ6L seizure related 6 homolog (mouse)-like
SIGLEC7 sialic acid binding Ig-like lectin 7
SPATA5L1 spermatogenesis associated 5-like 1
SPN sialophorin
SPRY4 sprouty homolog 4 (Drosophila)
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TFEC transcription factor EC
TMEM127 transmembrane protein 127
TPI1 triosephosphate isomerase 1
TPM3 tropomyosin 3
TRAPPC4 trafficking protein particle complex 4
TRIM8 tripartite motif containing 8
TUBA4B tubulin, alpha 4b
VEZF1 vascular endothelial zinc finger 1
VSNL1 visinin-like 1
WDR82 WD repeat domain 82
WT1-AS WT1 antisense RNA
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
ZFHX2 zinc finger homeobox 2

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACOT8 acyl-CoA thioesterase 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAP2 ArfGAP with dual PH domains 2
ALPK1 alpha-kinase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG14 autophagy related 14
ATXN2 ataxin 2
BAHD1 bromo adjacent homology domain containing 1
BANP BTG3 associated nuclear protein
BARD1 BRCA1 associated RING domain 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMI1 BMI1 proto-oncogene, polycomb ring finger
C19ORF54 chromosome 19 open reading frame 54
CA2 carbonic anhydrase II
CCDC86 coiled-coil domain containing 86
CCL4 chemokine (C-C motif) ligand 4
CD82 CD82 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CER1 cerberus 1, DAN family BMP antagonist
CISH cytokine inducible SH2-containing protein
CPNE1 copine I
CRYBB2P1 crystallin, beta B2 pseudogene 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
ERCC2 excision repair cross-complementation group 2
FAM160B2 family with sequence similarity 160, member B2
FCHSD2 FCH and double SH3 domains 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FMNL1 formin-like 1
GCLM glutamate-cysteine ligase, modifier subunit
GPATCH2 G patch domain containing 2
GRM6 glutamate receptor, metabotropic 6
GUSBP3 glucuronidase, beta pseudogene 3
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HIST3H2A histone cluster 3, H2a
HP haptoglobin
IL4R interleukin 4 receptor
INSIG2 insulin induced gene 2
IP6K2 inositol hexakisphosphate kinase 2
JMJD4 jumonji domain containing 4
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
MACROD1 MACRO domain containing 1
MAML1 mastermind-like 1 (Drosophila)
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MBIP MAP3K12 binding inhibitory protein 1
MID1IP1 MID1 interacting protein 1
NUP93 nucleoporin 93kDa
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PARG poly (ADP-ribose) glycohydrolase
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PMM2 phosphomannomutase 2
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
QPRT quinolinate phosphoribosyltransferase
QRICH1 glutamine-rich 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB4B RAB4B, member RAS oncogene family
RFXANK regulatory factor X-associated ankyrin-containing protein
RPS21 ribosomal protein S21
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEC61B Sec61 beta subunit
SETD1B SET domain containing 1B
SH2D3C SH2 domain containing 3C
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNX17 sorting nexin 17
SPI1 Spi-1 proto-oncogene
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAOK1 TAO kinase 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM7SF2 transmembrane 7 superfamily member 2
TMEM164 transmembrane protein 164
TMEM184B transmembrane protein 184B
TMEM243 transmembrane protein 243, mitochondrial
TP53BP2 tumor protein p53 binding protein 2
TREM1 triggering receptor expressed on myeloid cells 1
TSLIG2 tRNA splicing ligase complex subunit 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
URM1 ubiquitin related modifier 1
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
XPA xeroderma pigmentosum, complementation group A
ZNF197 zinc finger protein 197
ZSCAN5A zinc finger and SCAN domain containing 5A