hemicholinium-3216 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the hemicholinium-3216 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANGPTL2 angiopoietin-like 2
ANKRD6 ankyrin repeat domain 6
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATAT1 alpha tubulin acetyltransferase 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BEX1 brain expressed, X-linked 1
BNC2 basonuclin 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CADM4 cell adhesion molecule 4
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC102B coiled-coil domain containing 102B
CCRL2 chemokine (C-C motif) receptor-like 2
CD6 CD6 molecule
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
COL10A1 collagen, type X, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CRYBG3 beta-gamma crystallin domain containing 3
CTAGE5 CTAGE family, member 5
CYBB cytochrome b-245, beta polypeptide
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DENND5B DENN/MADD domain containing 5B
DRD2 dopamine receptor D2
DVL3 dishevelled segment polarity protein 3
EDA ectodysplasin A
ELOVL2 ELOVL fatty acid elongase 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPHB2 EPH receptor B2
EVA1B eva-1 homolog B (C. elegans)
FBXO21 F-box protein 21
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR85 G protein-coupled receptor 85
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRM1 glutamate receptor, metabotropic 1
HAP1 huntingtin-associated protein 1
HCRP1 hepatocellular carcinoma-related HCRP1
HIRA histone cell cycle regulator
HIST1H1T histone cluster 1, H1t
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HOXA4 homeobox A4
IL36RN interleukin 36 receptor antagonist
IQCG IQ motif containing G
JMJD4 jumonji domain containing 4
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIDINS220 kinase D-interacting substrate, 220kDa
KRT15 keratin 15, type I
LDHB lactate dehydrogenase B
LGALS9 lectin, galactoside-binding, soluble, 9
LIG3 ligase III, DNA, ATP-dependent
LIMS2 LIM and senescent cell antigen-like domains 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LTC4S leukotriene C4 synthase
LYZ lysozyme
MAGEA3 melanoma antigen family A3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEG3 maternally expressed 3 (non-protein coding)
MERTK MER proto-oncogene, tyrosine kinase
MTAP methylthioadenosine phosphorylase
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPTX1 neuronal pentraxin I
NRG2 neuregulin 2
PCDHB11 protocadherin beta 11
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PITX1 paired-like homeodomain 1
PRDX2 peroxiredoxin 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RHEB Ras homolog enriched in brain
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RUFY3 RUN and FYVE domain containing 3
RUNX2 runt-related transcription factor 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFXN3 sideroflexin 3
SOGA1 suppressor of glucose, autophagy associated 1
SRGN serglycin
SRRT serrate, RNA effector molecule
SSX3 synovial sarcoma, X breakpoint 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STIM1 stromal interaction molecule 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TESPA1 thymocyte expressed, positive selection associated 1
TTC38 tetratricopeptide repeat domain 38
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZFP36L1 ZFP36 ring finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF222 zinc finger protein 222
ZNF230 zinc finger protein 230
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADCY7 adenylate cyclase 7
AMPD2 adenosine monophosphate deaminase 2
APLP1 amyloid beta (A4) precursor-like protein 1
APOD apolipoprotein D
ARHGAP5 Rho GTPase activating protein 5
BCAS1 breast carcinoma amplified sequence 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP4 bone morphogenetic protein 4
BTF3P11 basic transcription factor 3 pseudogene 11
C14ORF105 chromosome 14 open reading frame 105
C2ORF54 chromosome 2 open reading frame 54
C9ORF9 chromosome 9 open reading frame 9
CAPG capping protein (actin filament), gelsolin-like
CCDC25 coiled-coil domain containing 25
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CFAP69 cilia and flagella associated protein 69
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHML choroideremia-like (Rab escort protein 2)
CNGB3 cyclic nucleotide gated channel beta 3
CNR2 cannabinoid receptor 2 (macrophage)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DUSP13 dual specificity phosphatase 13
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
FAM131A family with sequence similarity 131, member A
FLJ11710 uncharacterized protein FLJ11710
FLJ21369 uncharacterized protein FLJ21369
FMOD fibromodulin
FOSL1 FOS-like antigen 1
FRS2 fibroblast growth factor receptor substrate 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GIF gastric intrinsic factor (vitamin B synthesis)
GLTSCR1 glioma tumor suppressor candidate region gene 1
HIST1H1C histone cluster 1, H1c
HIST1H2AL histone cluster 1, H2al
HIST1H2BC histone cluster 1, H2bc
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXD11 homeobox D11
IL17RA interleukin 17 receptor A
INO80D INO80 complex subunit D
KLHL21 kelch-like family member 21
KLK5 kallikrein-related peptidase 5
KPNA5 karyopherin alpha 5 (importin alpha 6)
LAX1 lymphocyte transmembrane adaptor 1
LIG4 ligase IV, DNA, ATP-dependent
LRP2 low density lipoprotein receptor-related protein 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFAP2 microfibrillar-associated protein 2
MITF microphthalmia-associated transcription factor
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
NARFL nuclear prelamin A recognition factor-like
NUP62CL nucleoporin 62kDa C-terminal like
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLTP phospholipid transfer protein
PRR4 proline rich 4 (lacrimal)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPSN receptor-associated protein of the synapse
RASAL1 RAS protein activator like 1 (GAP1 like)
RCAN3 RCAN family member 3
RGS20 regulator of G-protein signaling 20
RIN1 Ras and Rab interactor 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1A SET domain containing 1A
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAB2 stabilin 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNC syncoilin, intermediate filament protein
TFDP3 transcription factor Dp family, member 3
TMEM209 transmembrane protein 209
TRAIP TRAF interacting protein
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC93B1 unc-93 homolog B1 (C. elegans)
WNT10B wingless-type MMTV integration site family, member 10B
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB6 zinc finger and BTB domain containing 6
ZIC3 Zic family member 3
ZNF34 zinc finger protein 34
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480
ZNF586 zinc finger protein 586
ZNF767P zinc finger family member 767, pseudogene