hemidesmosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cell-substrate junction that forms a point of contact between the basal surface of epithelial cells and the basal lamina. Morphologically resembles desmosomes; attached to intermediate filaments. (Gene Ontology, GO_0030056)
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Genes

109 proteins co-occuring with the hemidesmosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
COL17A1 collagen, type XVII, alpha 1 3.77532
COL7A1 collagen, type VII, alpha 1 2.07069
ITGB4 integrin, beta 4 2.00621
ITGA6 integrin, alpha 6 1.98124
LAMB3 laminin, beta 3 1.89662
LAMC2 laminin, gamma 2 1.76174
DST dystonin 1.53331
PLEC plectin 1.45194
LAMB2 laminin, beta 2 (laminin S) 1.27452
KRT3 keratin 3, type II 1.21997
LAMA3 laminin, alpha 3 1.19623
DSP desmoplakin 1.14801
CD79A CD79a molecule, immunoglobulin-associated alpha 1.12654
FN1 fibronectin 1 0.960707
DSG3 desmoglein 3 0.935488
DSG1 desmoglein 1 0.933129
KRT14 keratin 14, type I 0.931245
IVL involucrin 0.898572
NID1 nidogen 1 0.891169
FLG filaggrin 0.813946
KRT12 keratin 12, type I 0.766349
PPL periplakin 0.71768
KRT4 keratin 4, type II 0.717236
EIF6 eukaryotic translation initiation factor 6 0.648721
DSC2 desmocollin 2 0.647003
LOR loricrin 0.635868
TGFBI transforming growth factor, beta-induced, 68kDa 0.632451
FERMT1 fermitin family member 1 0.631598
CD151 CD151 molecule (Raph blood group) 0.626909
LAD1 ladinin 1 0.601487
MRPL12 mitochondrial ribosomal protein L12 0.544
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.539883
ELANE elastase, neutrophil expressed 0.537827
MACF1 microtubule-actin crosslinking factor 1 0.505131
FLII flightless I homolog (Drosophila) 0.487307
VCL vinculin 0.477636
DSC3 desmocollin 3 0.473617
EVPL envoplakin 0.468001
MUC21 mucin 21, cell surface associated 0.466799
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.464798
GPC6 glypican 6 0.463198
EIF1 eukaryotic translation initiation factor 1 0.45641
MMP9 matrix metallopeptidase 9 0.452427
DSG2 desmoglein 2 0.448848
CADM4 cell adhesion molecule 4 0.433407
BCAM basal cell adhesion molecule (Lutheran blood group) 0.423567
BHLHE23 basic helix-loop-helix family, member e23 0.420428
MST1 macrophage stimulating 1 0.419644
EGFR epidermal growth factor receptor 0.413382
TNC tenascin C 0.407919
MUC4 mucin 4, cell surface associated 0.405193
ERBB3 erb-b2 receptor tyrosine kinase 3 0.386593
SOX18 SRY (sex determining region Y)-box 18 0.385822
ERBB2IP erbb2 interacting protein 0.377738
SACS sacsin molecular chaperone 0.366623
ITGB6 integrin, beta 6 0.361659
ASB14 ankyrin repeat and SOCS box containing 14 0.354802
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.352142
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.336996
LPP LIM domain containing preferred translocation partner in lipoma 0.335864
APLF aprataxin and PNKP like factor 0.331342
ITGA9 integrin, alpha 9 0.328708
KRT10 keratin 10, type I 0.325702
KRT13 keratin 13, type I 0.301425
KRT1 keratin 1, type II 0.29994
KANK1 KN motif and ankyrin repeat domains 1 0.298084
SFN stratifin 0.292157
KRT5 keratin 5, type II 0.291417
BNC1 basonuclin 1 0.286983
JUP junction plakoglobin 0.276671
TP63 tumor protein p63 0.276671
MALL mal, T-cell differentiation protein-like 0.260931
FGF7 fibroblast growth factor 7 0.259109
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.258381
BHLHE22 basic helix-loop-helix family, member e22 0.258381
TMPRSS15 transmembrane protease, serine 15 0.254743
GPR83 G protein-coupled receptor 83 0.246407
GSN gelsolin 0.243158
GRB2 growth factor receptor-bound protein 2 0.241716
ERBB2 erb-b2 receptor tyrosine kinase 2 0.238478
TFDP3 transcription factor Dp family, member 3 0.232029
FBLIM1 filamin binding LIM protein 1 0.229176
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.228819
DSC1 desmocollin 1 0.227041
FBN1 fibrillin 1 0.222083
HOXC8 homeobox C8 0.220321
SCRIB scribbled planar cell polarity protein 0.213669
MMP2 matrix metallopeptidase 2 0.21228
KRT19 keratin 19, type I 0.21124
ECM1 extracellular matrix protein 1 0.203699
HDAC4 histone deacetylase 4 0.202346
SRRM1 serine/arginine repetitive matrix 1 0.198325
LHX2 LIM homeobox 2 0.196339
HOXA5 homeobox A5 0.191456
ITGB7 integrin, beta 7 0.189222
ITGB8 integrin, beta 8 0.188905
PKP3 plakophilin 3 0.186708
MBTPS2 membrane-bound transcription factor peptidase, site 2 0.186397
PLG plasminogen 0.185469
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.181524
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.180339
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.179167
LDB1 LIM domain binding 1 0.17141
DDN dendrin 0.169604
IL1A interleukin 1, alpha 0.16935
CDSN corneodesmosin 0.168847
CLCN2 chloride channel, voltage-sensitive 2 0.168101
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 0.162117
EREG epiregulin 0.161275