hemoglobin complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group. (Gene Ontology, GO_0005833)
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321 proteins co-occuring with the hemoglobin complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
ALB albumin 2.82834
INS insulin 2.72339
EPO erythropoietin 2.58738
HBB hemoglobin, beta 2.5636
HBA2 hemoglobin, alpha 2 2.56272
HBA1 hemoglobin, alpha 1 2.54069
FTL ferritin, light polypeptide 2.47601
FTH1 ferritin, heavy polypeptide 1 2.4717
SCN2A sodium channel, voltage gated, type II alpha subunit 2.44013
HBD hemoglobin, delta 2.36579
HP haptoglobin 2.35448
HPR haptoglobin-related protein 2.32881
TF transferrin 2.28611
CRP C-reactive protein, pentraxin-related 2.13768
MB myoglobin 2.12895
HBG2 hemoglobin, gamma G 2.00406
CYGB cytoglobin 1.93692
HBE1 hemoglobin, epsilon 1 1.92229
G6PD glucose-6-phosphate dehydrogenase 1.72745
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.68971
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.57875
ALPPL2 alkaline phosphatase, placental-like 2 1.52146
ALPL alkaline phosphatase, liver/bone/kidney 1.52033
ALPP alkaline phosphatase, placental 1.51976
DLL1 delta-like 1 (Drosophila) 1.50678
TFRC transferrin receptor 1.48814
FKBP4 FK506 binding protein 4, 59kDa 1.48645
SOD2 superoxide dismutase 2, mitochondrial 1.40858
ACE angiotensin I converting enzyme 1.38683
DPP4 dipeptidyl-peptidase 4 1.38461
F2 coagulation factor II (thrombin) 1.37243
GGT1 gamma-glutamyltransferase 1 1.33848
GPX5 glutathione peroxidase 5 1.31735
GPX4 glutathione peroxidase 4 1.30927
GPX1 glutathione peroxidase 1 1.29906
CAT catalase 1.29853
NGB neuroglobin 1.25706
F3 coagulation factor III (thromboplastin, tissue factor) 1.22257
CD4 CD4 molecule 1.18851
HAMP hepcidin antimicrobial peptide 1.12756
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.11276
ALLC allantoicase 1.11072
B2M beta-2-microglobulin 1.10919
EPOR erythropoietin receptor 1.099
PTH parathyroid hormone 1.06903
GCG glucagon 1.05136
TTR transthyretin 1.04984
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.0413
ALAD aminolevulinate dehydratase 1.01139
GSR glutathione reductase 0.982446
IL6 interleukin 6 0.976619
HBS1L HBS1-like translational GTPase 0.947333
GUCY2C guanylate cyclase 2C 0.936905
CD163 CD163 molecule 0.932187
NPR1 natriuretic peptide receptor 1 0.926543
REN renin 0.914376
RHD Rh blood group, D antigen 0.900426
IGF1 insulin-like growth factor 1 (somatomedin C) 0.887474
CD79A CD79a molecule, immunoglobulin-associated alpha 0.886551
CSN1S1 casein alpha s1 0.881016
RHCE Rh blood group, CcEe antigens 0.873647
KRT84 keratin 84, type II 0.86077
KLK3 kallikrein-related peptidase 3 0.857555
PGD phosphogluconate dehydrogenase 0.846532
FN3K fructosamine 3 kinase 0.844696
CP ceruloplasmin (ferroxidase) 0.838269
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.832761
LEP leptin 0.8245
EPGN epithelial mitogen 0.815322
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.804772
GLP1R glucagon-like peptide 1 receptor 0.782326
GIP gastric inhibitory polypeptide 0.762707
APOB apolipoprotein B 0.754983
GGT2 gamma-glutamyltransferase 2 0.753623
LTF lactotransferrin 0.746381
PKM pyruvate kinase, muscle 0.712351
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.711022
JAK2 Janus kinase 2 0.706156
CST3 cystatin C 0.698223
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.696026
HBZ hemoglobin, zeta 0.691202
HFE hemochromatosis 0.690764
GPI glucose-6-phosphate isomerase 0.688576
PKLR pyruvate kinase, liver and RBC 0.68639
KRT83 keratin 83, type II 0.680284
VWF von Willebrand factor 0.668559
TRIM37 tripartite motif containing 37 0.665529
NAAA N-acylethanolamine acid amidase 0.656033
IFNA2 interferon, alpha 2 0.640573
MGAM maltase-glucoamylase 0.639717
ESD esterase D 0.633732
F8 coagulation factor VIII, procoagulant component 0.633305
PRRC2A proline-rich coiled-coil 2A 0.633305
COG2 component of oligomeric golgi complex 2 0.632451
BPGM 2,3-bisphosphoglycerate mutase 0.630745
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.630318
CD6 CD6 molecule 0.629465
CTSD cathepsin D 0.627335
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 0.625206
SHB Src homology 2 domain containing adaptor protein B 0.62393
LAD1 ladinin 1 0.620529
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.620529
BCHE butyrylcholinesterase 0.619255
GSTTP1 glutathione S-transferase theta pseudogene 1 0.615861
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 0.613318
GSTT1 glutathione S-transferase theta 1 0.612471
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.597697
BLVRB biliverdin reductase B 0.596435
ACPP acid phosphatase, prostate 0.595173
AKR1C2 aldo-keto reductase family 1, member C2 0.592652
GPANK1 G patch domain and ankyrin repeats 1 0.590133
PLG plasminogen 0.586361
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.584686
SHBG sex hormone-binding globulin 0.577999
HBG1 hemoglobin, gamma A 0.575912
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.575078
GIF gastric intrinsic factor (vitamin B synthesis) 0.572578
FN3KRP fructosamine 3 kinase related protein 0.571329
SAMD4B sterile alpha motif domain containing 4B 0.568832
PGM1 phosphoglucomutase 1 0.563017
NPPA natriuretic peptide A 0.563017
APOA1 apolipoprotein A-I 0.5568
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.553905
IFNL3 interferon, lambda 3 0.550186
HK1 hexokinase 1 0.54936
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.546472
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.54606
KLF1 Kruppel-like factor 1 (erythroid) 0.54606
SORD sorbitol dehydrogenase 0.543176
ALAS2 5'-aminolevulinate synthase 2 0.543176
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.542764
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.525113
GSTA3 glutathione S-transferase alpha 3 0.523476
GSTA2 glutathione S-transferase alpha 2 0.521841
PLAT plasminogen activator, tissue 0.521841
GSTA4 glutathione S-transferase alpha 4 0.521432
GSTA1 glutathione S-transferase alpha 1 0.518981
F5 coagulation factor V (proaccelerin, labile factor) 0.514493
GC group-specific component (vitamin D binding protein) 0.512455
LYZ lysozyme 0.504318
GLO1 glyoxalase I 0.503912
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.503506
IL1B interleukin 1, beta 0.503099
HBQ1 hemoglobin, theta 1 0.500664
RETN resistin 0.49499
MPO myeloperoxidase 0.494585
AHSP alpha hemoglobin stabilizing protein 0.490539
FOXG1 forkhead box G1 0.490539
NCR3 natural cytotoxicity triggering receptor 3 0.490135
KNG1 kininogen 1 0.486904
CSH2 chorionic somatomammotropin hormone 2 0.484483
ACHE acetylcholinesterase (Yt blood group) 0.478843
FBXL20 F-box and leucine-rich repeat protein 20 0.476831
THPO thrombopoietin 0.476429
CSF3 colony stimulating factor 3 (granulocyte) 0.470005
PER1 period circadian clock 1 0.468802
CD34 CD34 molecule 0.468001
PGM2 phosphoglucomutase 2 0.466399
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.453621
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 0.45004
CYB5A cytochrome b5 type A (microsomal) 0.429465
MNX1 motor neuron and pancreas homeobox 1 0.425531
AFP alpha-fetoprotein 0.425531
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.42082
ADA adenosine deaminase 0.41886
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.415728
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.415728
GSTM1 glutathione S-transferase mu 1 0.415337
CHIT1 chitinase 1 (chitotriosidase) 0.413773
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.408699
GBA glucosidase, beta, acid 0.404804
TBPL1 TBP-like 1 0.40247
PNP purine nucleoside phosphorylase 0.401693
PGA3 pepsinogen 3, group I (pepsinogen A) 0.395098
PGA4 pepsinogen 4, group I (pepsinogen A) 0.395098
CD19 CD19 molecule 0.393936
APOL1 apolipoprotein L, 1 0.393549
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.393162
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.385822
LUC7L LUC7-like (S. cerevisiae) 0.38428
IGLV3-21 immunoglobulin lambda variable 3-21 0.383895
OR51B5 olfactory receptor, family 51, subfamily B, member 5 0.383895
C18ORF21 chromosome 18 open reading frame 21 0.383895
LHB luteinizing hormone beta polypeptide 0.378122
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.377738
ALAS1 5'-aminolevulinate synthase 1 0.371216
THBD thrombomodulin 0.369684
C3 complement component 3 0.359371
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.356705
IGLV2-8 immunoglobulin lambda variable 2-8 0.355944
LAP3 leucine aminopeptidase 3 0.352901
RPAP3 RNA polymerase II associated protein 3 0.351762
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.347208
PFKM phosphofructokinase, muscle 0.345692
GYPE glycophorin E (MNS blood group) 0.344178
BTC betacellulin 0.344178
TCN2 transcobalamin II 0.343421
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.335487
PHPT1 phosphohistidine phosphatase 1 0.330213
ICAM1 intercellular adhesion molecule 1 0.326453
IL10 interleukin 10 0.32345
NPPB natriuretic peptide B 0.318579
CA2 carbonic anhydrase II 0.317456
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.314839
TNNI3 troponin I type 3 (cardiac) 0.314091
FBP1 fructose-1,6-bisphosphatase 1 0.313718
CA1 carbonic anhydrase I 0.312597
TKT transketolase 0.312224
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.311478
C6ORF25 chromosome 6 open reading frame 25 0.308494
CD36 CD36 molecule (thrombospondin receptor) 0.308122
LBR lamin B receptor 0.308122
APEH acylaminoacyl-peptide hydrolase 0.303655
FLNA filamin A, alpha 0.294748
IPP intracisternal A particle-promoted polypeptide 0.294007
NOS3 nitric oxide synthase 3 (endothelial cell) 0.293637
GYPA glycophorin A (MNS blood group) 0.292527
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.291417
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.290308
PROS1 protein S (alpha) 0.289938
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.28846
PILRB paired immunoglobin-like type 2 receptor beta 0.284769
IGLV2-14 immunoglobulin lambda variable 2-14 0.284769
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.282189
MRPL49 mitochondrial ribosomal protein L49 0.280716
GCK glucokinase (hexokinase 4) 0.279245
IGFBP1 insulin-like growth factor binding protein 1 0.277406
GHRL ghrelin/obestatin prepropeptide 0.277038
VCAM1 vascular cell adhesion molecule 1 0.277038
LDHA lactate dehydrogenase A 0.275202
TPMT thiopurine S-methyltransferase 0.272267
EDN3 endothelin 3 0.2719
SCARB2 scavenger receptor class B, member 2 0.270434
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.270068
IL3 interleukin 3 0.270068
CTSL cathepsin L 0.265677
LIN37 lin-37 DREAM MuvB core complex component 0.265677
AVP arginine vasopressin 0.264946
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.26312
NOVA2 neuro-oncological ventral antigen 2 0.26312
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.262755
TSKU tsukushi, small leucine rich proteoglycan 0.260931
SELE selectin E 0.25547
TNF tumor necrosis factor 0.254743
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.246046
IFNA1 interferon, alpha 1 0.244962
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.244962
LY96 lymphocyte antigen 96 0.24424
PHB prohibitin 0.243879
SEC23B Sec23 homolog B (S. cerevisiae) 0.241716
ZDHHC23 zinc finger, DHHC-type containing 23 0.241356
LPA lipoprotein, Lp(a) 0.239197
GH1 growth hormone 1 0.236324
SCAND1 SCAN domain containing 1 0.233459
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.231672
EPB41 erythrocyte membrane protein band 4.1 0.230601
MEGF6 multiple EGF-like-domains 6 0.229532
ZGLP1 zinc finger, GATA-like protein 1 0.221378
AK2 adenylate kinase 2 0.221378
CTSB cathepsin B 0.220673
IL1RN interleukin 1 receptor antagonist 0.220321
SST somatostatin 0.219969
IGFBP3 insulin-like growth factor binding protein 3 0.21646
FABP9 fatty acid binding protein 9, testis 0.215063
BBX bobby sox homolog (Drosophila) 0.21228
SCARB1 scavenger receptor class B, member 1 0.21124
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.21124
GATA2 GATA binding protein 2 0.210894
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.209513
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.209169
TMPRSS6 transmembrane protease, serine 6 0.206423
SPTB spectrin, beta, erythrocytic 0.206082
DIEXF digestive organ expansion factor homolog (zebrafish) 0.203699
PF4 platelet factor 4 0.203361
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.202009
MRS2 MRS2 magnesium transporter 0.201335
LBP lipopolysaccharide binding protein 0.190495
POMC proopiomelanocortin 0.189539
PER2 period circadian clock 2 0.189222
CYB5R3 cytochrome b5 reductase 3 0.18859
CTRC chymotrypsin C (caldecrin) 0.188274
PPT1 palmitoyl-protein thioesterase 1 0.18702
C5 complement component 5 0.186397
FECH ferrochelatase 0.185777
LCN2 lipocalin 2 0.185469
PTOV1 prostate tumor overexpressed 1 0.182422
CD5 CD5 molecule 0.181823
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae) 0.181524
PPARG peroxisome proliferator-activated receptor gamma 0.180339
MMD monocyte to macrophage differentiation-associated 0.180339
BTN2A1 butyrophilin, subfamily 2, member A1 0.179459
DNAH8 dynein, axonemal, heavy chain 8 0.178011
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.176024
HN1 hematological and neurological expressed 1 0.174635
GALK2 galactokinase 2 0.174635
SELENBP1 selenium binding protein 1 0.173814
ZNF146 zinc finger protein 146 0.173543
PGC progastricsin (pepsinogen C) 0.173003
ANK1 ankyrin 1, erythrocytic 0.172735
ETV3 ets variant 3 0.172468
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.17141
GAS6 growth arrest-specific 6 0.170888
RRBP1 ribosome binding protein 1 0.170114
CABIN1 calcineurin binding protein 1 0.169099
GH2 growth hormone 2 0.169099
CA10 carbonic anhydrase X 0.167611
VEGFA vascular endothelial growth factor A 0.165231
RARS arginyl-tRNA synthetase 0.16342
IL2 interleukin 2 0.1632
PON1 paraoxonase 1 0.162763
HSPA4 heat shock 70kDa protein 4 0.160658
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.160053
IGLV5-52 immunoglobulin lambda variable 5-52 0.160053
POLL polymerase (DNA directed), lambda 0.159856
STPG1 sperm-tail PG-rich repeat containing 1 0.159268
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.158692
FBL fibrillarin 0.158129
LIN7A lin-7 homolog A (C. elegans) 0.157578
CARTPT CART prepropeptide 0.157039
MGP matrix Gla protein 0.156342
MDH1 malate dehydrogenase 1, NAD (soluble) 0.156342