hepatitis b Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus, which is transmitted_by sexual contact, transmitted_by blood transfusions, and transmitted_by fomites like needles or syringes. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice. (Human Disease Ontology, DOID_2043)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:2043
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Genes

73 genes associated with the disease hepatitis b in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 2.6877
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 2.60413
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 2.38233
GGT1 gamma-glutamyltransferase 1 1.99363
SH2B3 SH2B adaptor protein 3 1.96871
TCF19 transcription factor 19 1.95898
KIF1B kinesin family member 1B 1.95032
BTNL2 butyrophilin-like 2 1.9199
C2 complement component 2 1.91853
LY6G5B lymphocyte antigen 6 complex, locus G5B 1.88174
BAG6 BCL2-associated athanogene 6 1.86137
PRRC2A proline-rich coiled-coil 2A 1.85327
NELFE negative elongation factor complex member E 1.84882
GPANK1 G patch domain and ankyrin repeats 1 1.8372
LY6G6F lymphocyte antigen 6 complex, locus G6F 1.81775
LY6G6C lymphocyte antigen 6 complex, locus G6C 1.78835
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.77661
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.73579
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.70184
PNPLA3 patatin-like phospholipase domain containing 3 1.68104
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.68078
GP1BA glycoprotein Ib (platelet), alpha polypeptide 1.6791
TNXB tenascin XB 1.62503
SLC44A4 solute carrier family 44, member 4 1.62435
THPO thrombopoietin 1.59415
C6ORF10 chromosome 6 open reading frame 10 1.5843
NOTCH4 notch 4 1.57088
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.52118
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.51185
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.49551
HLA-DPB2 major histocompatibility complex, class II, DP beta 2 (pseudogene) 1.49335
HLA-C major histocompatibility complex, class I, C 1.46901
GCKR glucokinase (hexokinase 4) regulator 1.45969
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.45857
BRAP BRCA1 associated protein 1.45121
MICA MHC class I polypeptide-related sequence A 1.4474
MIR3135B microRNA 3135b 1.42467
STK26 serine/threonine protein kinase 26 1.40726
CCHCR1 coiled-coil alpha-helical rod protein 1 1.39447
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.39396
DDR1 discoidin domain receptor tyrosine kinase 1 1.39197
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 1.38169
HLA-DRA major histocompatibility complex, class II, DR alpha 1.37555
SFTA2 surfactant associated 2 1.3711
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 1.34516
GPSM3 G-protein signaling modulator 3 1.3381
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.33557
RING1 ring finger protein 1 1.3016
FRMD7 FERM domain containing 7 1.29372
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 1.24218
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 1.23617
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 1.23544
YDJC YdjC homolog (bacterial) 1.22189
SCTR secretin receptor 1.18459
ACOT9 acyl-CoA thioesterase 9 1.13248
LOC643542 uncharacterized LOC643542 1.08274
EFHC2 EF-hand domain (C-terminal) containing 2 1.07422
EXOC1 exocyst complex component 1 1.05742
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 1.04514
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 1.03953
PBX2 pre-B-cell leukemia homeobox 2 0.999491
COL4A1 collagen, type IV, alpha 1 0.993521
HSF2 heat shock transcription factor 2 0.991774
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.989716
DMD dystrophin 0.987533
KLF5 Kruppel-like factor 5 (intestinal) 0.983144
CDH13 cadherin 13 0.972161
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.966942
ARHGAP15 Rho GTPase activating protein 15 0.960535
NUP205 nucleoporin 205kDa 0.876244
FHIT fragile histidine triad 0.875106
PYGL phosphorylase, glycogen, liver 0.87015
FAM155A family with sequence similarity 155, member A 0.677699