hepatitis b Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus, which is transmitted_by sexual contact, transmitted_by blood transfusions, and transmitted_by fomites like needles or syringes. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice. (Human Disease Ontology, DOID_2043)
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Genes

53 genes associated with the disease hepatitis b in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
APOE apolipoprotein E
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CDC42 cell division cycle 42
CIITA class II, major histocompatibility complex, transactivator
CXCL12 chemokine (C-X-C motif) ligand 12
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ELF2 E74-like factor 2 (ets domain transcription factor)
GBP2 guanylate binding protein 2, interferon-inducible
GPR78 G protein-coupled receptor 78
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNG interferon, gamma
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL12B interleukin 12B
IL18 interleukin 18
IL19 interleukin 19
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
JAK1 Janus kinase 1
LTA lymphotoxin alpha
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MX1 MX dynamin-like GTPase 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
STAT1 signal transducer and activator of transcription 1, 91kDa
TBX21 T-box 21
TNF tumor necrosis factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
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