hepatitis c Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in inflammation located_in liver, has_material_basis_in Hepatitis C virus, which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice. (Human Disease Ontology, DOID_1883)
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Genes

75 genes associated with the disease hepatitis c in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADA adenosine deaminase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK9 adenylate kinase 9
ALDOB aldolase B, fructose-bisphosphate
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APOE apolipoprotein E
BMP8B bone morphogenetic protein 8b
CABIN1 calcineurin binding protein 1
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD34 CD34 molecule
CD4 CD4 molecule
CD80 CD80 molecule
CD81 CD81 molecule
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR2 chemokine (C-X-C motif) receptor 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAS Fas cell surface death receptor
FGL1 fibrinogen-like 1
GRAP2 GRB2-related adaptor protein 2
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
IFI27 interferon, alpha-inducible protein 27
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL18R1 interleukin 18 receptor 1
IL19 interleukin 19
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL20 interleukin 20
IL22 interleukin 22
IL24 interleukin 24
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
IL6 interleukin 6
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LDLR low density lipoprotein receptor
LTA lymphotoxin alpha
LTBP2 latent transforming growth factor beta binding protein 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MPO myeloperoxidase
MX1 MX dynamin-like GTPase 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PRL prolactin
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SP110 SP110 nuclear body protein
STAT5A signal transducer and activator of transcription 5A
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
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