hepatoblastoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

249 genes co-occuring with the disease hepatoblastoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
AFP alpha-fetoprotein 2.25795
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 1.43991
IGF2 insulin-like growth factor 2 1.34592
GPC3 glypican 3 1.19748
GTSE1 G-2 and S-phase expressed 1 1.16863
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.14645
ABLIM2 actin binding LIM protein family, member 2 1.14348
KLHL22 kelch-like family member 22 1.14348
RNF169 ring finger protein 169 1.14348
OR5I1 olfactory receptor, family 5, subfamily I, member 1 1.14348
CDC20B cell division cycle 20B 1.0606
PANK3 pantothenate kinase 3 1.0109
ABLIM3 actin binding LIM protein family, member 3 0.999503
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.918848
CADM1 cell adhesion molecule 1 0.885979
SAR1B secretion associated, Ras related GTPase 1B 0.840934
PLAG1 pleiomorphic adenoma gene 1 0.826589
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.80977
HRAS Harvey rat sarcoma viral oncogene homolog 0.777795
RNF167 ring finger protein 167 0.773705
CRYZ crystallin, zeta (quinone reductase) 0.749237
APOB apolipoprotein B 0.74436
NQO1 NAD(P)H dehydrogenase, quinone 1 0.741111
KRT7 keratin 7, type II 0.741111
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 0.734622
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 0.714811
IGHD3-10 immunoglobulin heavy diversity 3-10 0.707559
APOA1 apolipoprotein A-I 0.705949
CDO1 cysteine dioxygenase type 1 0.698313
ABLIM1 actin binding LIM protein 1 0.694702
SLC22A18 solute carrier family 22, member 18 0.689893
TP53 tumor protein p53 0.685891
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 0.685091
MET MET proto-oncogene, receptor tyrosine kinase 0.681894
KRT83 keratin 83, type II 0.672722
CDON cell adhesion associated, oncogene regulated 0.665563
GLUL glutamate-ammonia ligase 0.6608
NUMBL numb homolog (Drosophila)-like 0.646165
AXIN2 axin 2 0.644586
SMC2 structural maintenance of chromosomes 2 0.636708
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.636315
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.624927
CCND1 cyclin D1 0.615138
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.58939
GLI1 GLI family zinc finger 1 0.588222
JAM2 junctional adhesion molecule 2 0.586276
PAX7 paired box 7 0.583941
T T, brachyury homolog (mouse) 0.583163
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.579661
RENBP renin binding protein 0.574994
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.566443
CXXC4 CXXC finger protein 4 0.55945
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.554403
BCL2L1 BCL2-like 1 0.540055
KRT19 keratin 19, type I 0.535409
KREMEN1 kringle containing transmembrane protein 1 0.532701
ALB albumin 0.528835
DLK1 delta-like 1 homolog (Drosophila) 0.524202
FN1 fibronectin 1 0.518805
ZC3H13 zinc finger CCCH-type containing 13 0.514571
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.514571
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.507657
MIR214 microRNA 214 0.497321
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.49274
GPC4 glypican 4 0.492359
NAP1L1 nucleosome assembly protein 1-like 1 0.491215
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 0.490454
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 0.488549
BAAT bile acid CoA:amino acid N-acyltransferase 0.488169
LPA lipoprotein, Lp(a) 0.483224
MARVELD2 MARVEL domain containing 2 0.480945
CCL15 chemokine (C-C motif) ligand 15 0.46655
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.465794
BAX BCL2-associated X protein 0.460129
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.457109
PCSK9 proprotein convertase subtilisin/kexin type 9 0.453339
RBMY1A1 RNA binding motif protein, Y-linked, family 1, member A1 0.446935
POR P450 (cytochrome) oxidoreductase 0.4443
ANXA10 annexin A10 0.440162
BIRC5 baculoviral IAP repeat containing 5 0.431144
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.42814
FOXM1 forkhead box M1 0.42739
IL6 interleukin 6 0.423265
APOA2 apolipoprotein A-II 0.42289
NDC80 NDC80 kinetochore complex component 0.418768
NKD1 naked cuticle homolog 1 (Drosophila) 0.41727
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.415773
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.415398
TAT tyrosine aminotransferase 0.413901
NOTCH2 notch 2 0.413527
PTCRA pre T-cell antigen receptor alpha 0.412779
GSTA1 glutathione S-transferase alpha 1 0.412779
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.412031
COG1 component of oligomeric golgi complex 1 0.410909
MSH4 mutS homolog 4 0.409787
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.401572
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 0.401572
KRT8 keratin 8, type II 0.394863
DTX1 deltex 1, E3 ubiquitin ligase 0.391513
WT1 Wilms tumor 1 0.390769
LDLR low density lipoprotein receptor 0.382966
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.382966
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.380739
NCK1 NCK adaptor protein 1 0.378514
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.378514
CAPRIN2 caprin family member 2 0.377402
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein 0.373328
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.370737
HNF1B HNF1 homeobox B 0.364824
NFIA nuclear factor I/A 0.356341
FOXG1 forkhead box G1 0.354868
CD44 CD44 molecule (Indian blood group) 0.354868
RBBP9 retinoblastoma binding protein 9 0.354499
IGHV4-39 immunoglobulin heavy variable 4-39 0.353027
GSTA2 glutathione S-transferase alpha 2 0.352659
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.349717
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.347879
NLE1 notchless homolog 1 (Drosophila) 0.345675
SALL4 spalt-like transcription factor 4 0.345675
NFIB nuclear factor I/B 0.343106
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 0.340173
THPO thrombopoietin 0.337975
ICAM1 intercellular adhesion molecule 1 0.332487
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.331756
MTO1 mitochondrial tRNA translation optimization 1 0.331756
MGAM maltase-glucoamylase 0.3292
SPOP speckle-type POZ protein 0.328834
FANCL Fanconi anemia, complementation group L 0.328469
CEP104 centrosomal protein 104kDa 0.316819
THY1 Thy-1 cell surface antigen 0.313552
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.311014
HNF4A hepatocyte nuclear factor 4, alpha 0.30848
STK10 serine/threonine kinase 10 0.308118
AKR1C4 aldo-keto reductase family 1, member C4 0.302337
PLAGL2 pleiomorphic adenoma gene-like 2 0.300533
FOSL1 FOS-like antigen 1 0.300173
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.300173
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.297651
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.295851
ENO2 enolase 2 (gamma, neuronal) 0.295851
APC adenomatous polyposis coli 0.294413
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.292257
CPM carboxypeptidase M 0.290821
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.289744
TNF tumor necrosis factor 0.287235
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.284728
PROM1 prominin 1 0.284013
CNTFR ciliary neurotrophic factor receptor 0.280082
STK3 serine/threonine kinase 3 0.279011
GSTA3 glutathione S-transferase alpha 3 0.278297
HNF1A HNF1 homeobox A 0.277227
MT1G metallothionein 1G 0.276514
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.276158
GSTA4 glutathione S-transferase alpha 4 0.275801
PTCH1 patched 1 0.274732
CD34 CD34 molecule 0.273308
PARP1 poly (ADP-ribose) polymerase 1 0.272241
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.270464
SCGB1D1 secretoglobin, family 1D, member 1 0.270108
TRPV3 transient receptor potential cation channel, subfamily V, member 3 0.268687
NBPF1 neuroblastoma breakpoint family, member 1 0.268687
SQLE squalene epoxidase 0.264785
JUND jun D proto-oncogene 0.264431
HAVCR1 hepatitis A virus cellular receptor 1 0.263368
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.263014
IGKV3-20 immunoglobulin kappa variable 3-20 0.26266
CDH13 cadherin 13 0.260891
DPEP1 dipeptidase 1 (renal) 0.255946
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.255594
KRT18 keratin 18, type I 0.255241
ERN1 endoplasmic reticulum to nucleus signaling 1 0.254536
CCNC cyclin C 0.254536
FZD2 frizzled class receptor 2 0.254183
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.24996
ULBP1 UL16 binding protein 1 0.248905
NCAM1 neural cell adhesion molecule 1 0.243295
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.242245
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.241895
HBA2 hemoglobin, alpha 2 0.241546
PPA1 pyrophosphatase (inorganic) 1 0.240847
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.240148
AXIN1 axin 1 0.239799
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.239799
IHH indian hedgehog 0.23945
PKP2 plakophilin 2 0.238054
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.237357
NPAT nuclear protein, ataxia-telangiectasia locus 0.234225
AMER1 APC membrane recruitment protein 1 0.233878
MTTP microsomal triglyceride transfer protein 0.232836
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.232836
NT5C2 5'-nucleotidase, cytosolic II 0.231795
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.230063
LATS1 large tumor suppressor kinase 1 0.227642
SMC1A structural maintenance of chromosomes 1A 0.223165
CCNG2 cyclin G2 0.221793
MINK1 misshapen-like kinase 1 0.221108
ALPPL2 alkaline phosphatase, placental-like 2 0.21974
ALPP alkaline phosphatase, placental 0.219398
STK26 serine/threonine protein kinase 26 0.219057
ALPL alkaline phosphatase, liver/bone/kidney 0.218715
ESM1 endothelial cell-specific molecule 1 0.217693
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4 0.214636
LIN28B lin-28 homolog B (C. elegans) 0.212608
SHB Src homology 2 domain containing adaptor protein B 0.211597
FASLG Fas ligand (TNF superfamily, member 6) 0.210589
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.209918
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 0.206913
DGAT1 diacylglycerol O-acyltransferase 1 0.205254
MOGS mannosyl-oligosaccharide glucosidase 0.201635
MLANA melan-A 0.200656
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.199681
ANGPTL3 angiopoietin-like 3 0.199681
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.198064
PPARA peroxisome proliferator-activated receptor alpha 0.196779
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 0.194232
GTF2B general transcription factor IIB 0.193285
DAD1 defender against cell death 1 0.192971
TMEM51 transmembrane protein 51 0.192971
KEAP1 kelch-like ECH-associated protein 1 0.191719
TOP1 topoisomerase (DNA) I 0.191408
PANK1 pantothenate kinase 1 0.190786
JUN jun proto-oncogene 0.188326
GNMT glycine N-methyltransferase 0.184128
NEK2 NIMA-related kinase 2 0.183835
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.182957
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.180652
MRS2 MRS2 magnesium transporter 0.178682
IL1B interleukin 1, beta 0.178126
HHIP hedgehog interacting protein 0.177851
MST1 macrophage stimulating 1 0.177576
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.175947
CAT catalase 0.175947
EIF4E eukaryotic translation initiation factor 4E 0.173832
KRAS Kirsten rat sarcoma viral oncogene homolog 0.172544
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.171535
CCNG1 cyclin G1 0.170544
PLAGL1 pleiomorphic adenoma gene-like 1 0.170544
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.168617
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.167915
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.167452
CD99 CD99 molecule 0.166095
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.163111
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.162908
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.162109
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.160387
MIR96 microRNA 96 0.15948
CREBBP CREB binding protein 0.159302
PGR progesterone receptor 0.148167
ESR1 estrogen receptor 1 0.14384