hepatocarcinogenesis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

182 genes co-occuring with the biological term hepatocarcinogenesis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
AFP alpha-fetoprotein
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APC adenomatous polyposis coli
AR androgen receptor
AREG amphiregulin
ARG1 arginase 1
ATF6 activating transcription factor 6
AURKB aurora kinase B
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BTG2 BTG family, member 2
CADM1 cell adhesion molecule 1
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CCNE1 cyclin E1
CD109 CD109 molecule
CD34 CD34 molecule
CDK20 cyclin-dependent kinase 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CKMT1B creatine kinase, mitochondrial 1B
COPS5 COP9 signalosome subunit 5
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCLK1 doublecortin-like kinase 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DICER1 dicer 1, ribonuclease type III
DLC1 DLC1 Rho GTPase activating protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOT1L DOT1-like histone H3K79 methyltransferase
EFNA5 ephrin-A5
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
EGR1 early growth response 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2 coagulation factor II (thrombin)
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FOXM1 forkhead box M1
FOXP3 forkhead box P3
FZD7 frizzled class receptor 7
GDF2 growth differentiation factor 2
GFER growth factor, augmenter of liver regeneration
GJA1 gap junction protein, alpha 1, 43kDa
GJB1 gap junction protein, beta 1, 32kDa
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRN granulin
GSTP1 glutathione S-transferase pi 1
HDAC2 histone deacetylase 2
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK2 hexokinase 2
HNF1A HNF1 homeobox A
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL6 interleukin 6
ILK integrin-linked kinase
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KRT19 keratin 19, type I
LAMA4 laminin, alpha 4
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LEPR leptin receptor
LHX4 LIM homeobox 4
LIN28A lin-28 homolog A (C. elegans)
LIN28B lin-28 homolog B (C. elegans)
LRP6 low density lipoprotein receptor-related protein 6
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAPK1 mitogen-activated protein kinase 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MIR122 microRNA 122
MIR148A microRNA 148a
MIR195 microRNA 195
MIR216A microRNA 216a
MIR221 microRNA 221
MIR363 microRNA 363
MIR497 microRNA 497
MIR520B microRNA 520b
MIR602 microRNA 602
MIR7-1 microRNA 7-1
MIR93 microRNA 93
MTDH metadherin
MYC v-myc avian myelocytomatosis viral oncogene homolog
MZB1 marginal zone B and B1 cell-specific protein
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NDRG3 NDRG family member 3
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOTCH1 notch 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
PARK7 parkinson protein 7
PAX5 paired box 5
PCNA proliferating cell nuclear antigen
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEBP1 phosphatidylethanolamine binding protein 1
PGAM1 phosphoglycerate mutase 1 (brain)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PML promyelocytic leukemia
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PRDX2 peroxiredoxin 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RPL36 ribosomal protein L36
RUNX3 runt-related transcription factor 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGSM3 small G protein signaling modulator 3
SIRT1 sirtuin 1
SIRT7 sirtuin 7
SLC38A1 solute carrier family 38, member 1
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMO smoothened, frizzled class receptor
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOX4 SRY (sex determining region Y)-box 4
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STMN1 stathmin 1
SULF1 sulfatase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SUOX sulfite oxidase
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNF tumor necrosis factor
TP53 tumor protein p53
TP73 tumor protein p73
TPM3 tropomyosin 3
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC2 tuberous sclerosis 2
TXNIP thioredoxin interacting protein
URGCP upregulator of cell proliferation
URI1 URI1, prefoldin-like chaperone
WFDC1 WAP four-disulfide core domain 1
WNT11 wingless-type MMTV integration site family, member 11
WNT3 wingless-type MMTV integration site family, member 3
WWOX WW domain containing oxidoreductase
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
YBX3 Y box binding protein 3
ZHX1 zinc fingers and homeoboxes 1
ZNF689 zinc finger protein 689