heptaminol-1825 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the heptaminol-1825 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
AEN apoptosis enhancing nuclease
AKAP9 A kinase (PRKA) anchor protein 9
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP12 Rho GTPase activating protein 12
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASPH aspartate beta-hydroxylase
ATP13A3 ATPase type 13A3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCAS4 breast carcinoma amplified sequence 4
BTD biotinidase
C17ORF80 chromosome 17 open reading frame 80
CAPN2 calpain 2, (m/II) large subunit
CDC37L1 cell division cycle 37-like 1
CDC5L cell division cycle 5-like
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDV3 CDV3 homolog (mouse)
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLIC4 chloride intracellular channel 4
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNOT4 CCR4-NOT transcription complex, subunit 4
CORO1A coronin, actin binding protein, 1A
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DGKA diacylglycerol kinase, alpha 80kDa
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
FABP4 fatty acid binding protein 4, adipocyte
FBN1 fibrillin 1
FBXL18 F-box and leucine-rich repeat protein 18
FGF1 fibroblast growth factor 1 (acidic)
FSCN1 fascin actin-bundling protein 1
GDAP1 ganglioside induced differentiation associated protein 1
GM2A GM2 ganglioside activator
GSR glutathione reductase
HHEX hematopoietically expressed homeobox
HIST1H3G histone cluster 1, H3g
IL33 interleukin 33
ITGA6 integrin, alpha 6
ITM2B integral membrane protein 2B
JRK Jrk homolog (mouse)
KIAA0485 uncharacterized LOC57235
KIF22 kinesin family member 22
LARP4B La ribonucleoprotein domain family, member 4B
LEPROT leptin receptor overlapping transcript
LIN7C lin-7 homolog C (C. elegans)
LPIN2 lipin 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MATN3 matrilin 3
MAX MYC associated factor X
MBNL1 muscleblind-like splicing regulator 1
MCM9 minichromosome maintenance complex component 9
MET MET proto-oncogene, receptor tyrosine kinase
MXD4 MAX dimerization protein 4
NFYA nuclear transcription factor Y, alpha
NNT nicotinamide nucleotide transhydrogenase
NRP1 neuropilin 1
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUP98 nucleoporin 98kDa
NXT2 nuclear transport factor 2-like export factor 2
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PALMD palmdelphin
PAPOLA poly(A) polymerase alpha
PAWR PRKC, apoptosis, WT1, regulator
PDS5B PDS5 cohesin associated factor B
PHF20 PHD finger protein 20
PIAS1 protein inhibitor of activated STAT, 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKCH protein kinase C, eta
PRR15L proline rich 15-like
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARG retinoic acid receptor, gamma
RDX radixin
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
SCAMP1 secretory carrier membrane protein 1
SGSM3 small G protein signaling modulator 3
SLC35E1 solute carrier family 35, member E1
SLC43A3 solute carrier family 43, member 3
SQLE squalene epoxidase
TM7SF2 transmembrane 7 superfamily member 2
TMEM194A transmembrane protein 194A
TMEM209 transmembrane protein 209
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM2 tripartite motif containing 2
TRIM32 tripartite motif containing 32
TST thiosulfate sulfurtransferase (rhodanese)
UBAP1 ubiquitin associated protein 1
VGLL3 vestigial-like family member 3
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF107 zinc finger protein 107
ZNF286A zinc finger protein 286A
ZNF358 zinc finger protein 358
ZNF589 zinc finger protein 589
ZNF84 zinc finger protein 84

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
AMDHD2 amidohydrolase domain containing 2
BDNF brain-derived neurotrophic factor
BTBD2 BTB (POZ) domain containing 2
C17ORF70 chromosome 17 open reading frame 70
CCNJL cyclin J-like
CFL1 cofilin 1 (non-muscle)
CGREF1 cell growth regulator with EF-hand domain 1
CLEC16A C-type lectin domain family 16, member A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CTSF cathepsin F
DEAF1 DEAF1 transcription factor
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAL4 dynein, axonemal, light chain 4
DNMBP dynamin binding protein
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EFNB1 ephrin-B1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FLJ22184
FOXC1 forkhead box C1
FUZ fuzzy planar cell polarity protein
GAL3ST4 galactose-3-O-sulfotransferase 4
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GID4 GID complex subunit 4
HDAC7 histone deacetylase 7
HIST1H2AG histone cluster 1, H2ag
HIST1H3B histone cluster 1, H3b
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL32 interleukin 32
INF2 inverted formin, FH2 and WH2 domain containing
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCTD15 potassium channel tetramerization domain containing 15
KCTD20 potassium channel tetramerization domain containing 20
KIAA0894 KIAA0894 protein
KIFC3 kinesin family member C3
MANBA mannosidase, beta A, lysosomal
MEIS1 Meis homeobox 1
MGC12488
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MRPL46 mitochondrial ribosomal protein L46
MUC3B mucin 3B, cell surface associated
MXRA8 matrix-remodelling associated 8
NCS1 neuronal calcium sensor 1
NPM3 nucleophosmin/nucleoplasmin 3
NSD1 nuclear receptor binding SET domain protein 1
NUBP2 nucleotide binding protein 2
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PCOLCE procollagen C-endopeptidase enhancer
PDGFRL platelet-derived growth factor receptor-like
PEX26 peroxisomal biogenesis factor 26
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLH polymerase (DNA directed), eta
PRICKLE3 prickle homolog 3 (Drosophila)
RBL1 retinoblastoma-like 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
SDC3 syndecan 3
SEPP1 selenoprotein P, plasma, 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SMA4 glucuronidase, beta pseudogene
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPATA2L spermatogenesis associated 2-like
SPEG SPEG complex locus
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TAGLN3 transgelin 3
TBC1D2 TBC1 domain family, member 2
TCTN2 tectonic family member 2
THAP4 THAP domain containing 4
TMCC2 transmembrane and coiled-coil domain family 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
TUBG2 tubulin, gamma 2
UBTD1 ubiquitin domain containing 1
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
VASH2 vasohibin 2
VASP vasodilator-stimulated phosphoprotein
ZFYVE16 zinc finger, FYVE domain containing 16
ZMAT5 zinc finger, matrin-type 5
ZNF205 zinc finger protein 205
ZNF324 zinc finger protein 324
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574
ZNF669 zinc finger protein 669
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862