heptaminol-6015 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the heptaminol-6015 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCK4 aarF domain containing kinase 4
AK1 adenylate kinase 1
ANGPTL2 angiopoietin-like 2
ANP32A-IT1 ANP32A intronic transcript 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARL4D ADP-ribosylation factor-like 4D
ATF5 activating transcription factor 5
ATF7 activating transcription factor 7
ATXN2L ataxin 2-like
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C21ORF2 chromosome 21 open reading frame 2
CCDC64 coiled-coil domain containing 64
CD53 CD53 molecule
CES3 carboxylesterase 3
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC7A C-type lectin domain family 7, member A
COL4A1 collagen, type IV, alpha 1
COL5A1 collagen, type V, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CRY2 cryptochrome circadian clock 2
DOC2B double C2-like domains, beta
DOK4 docking protein 4
DUSP26 dual specificity phosphatase 26 (putative)
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EPHB2 EPH receptor B2
EPHX3 epoxide hydrolase 3
EXD3 exonuclease 3'-5' domain containing 3
FHL1 four and a half LIM domains 1
FSCN1 fascin actin-bundling protein 1
GAB1 GRB2-associated binding protein 1
GK2 glycerol kinase 2
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GRK5 G protein-coupled receptor kinase 5
GSTM5 glutathione S-transferase mu 5
HAP1 huntingtin-associated protein 1
HHLA1 HERV-H LTR-associating 1
HOXB9 homeobox B9
HPSE2 heparanase 2 (inactive)
ISL1 ISL LIM homeobox 1
JAG1 jagged 1
KDR kinase insert domain receptor
KIAA0930 KIAA0930
LAMC2 laminin, gamma 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MCM3AP minichromosome maintenance complex component 3 associated protein
MED16 mediator complex subunit 16
MRPS18C mitochondrial ribosomal protein S18C
MXD4 MAX dimerization protein 4
NEURL1 neuralized E3 ubiquitin protein ligase 1
NGDN neuroguidin, EIF4E binding protein
NYX nyctalopin
OAZ3 ornithine decarboxylase antizyme 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSBPL10 oxysterol binding protein-like 10
PDE4DIP phosphodiesterase 4D interacting protein
PGAP1 post-GPI attachment to proteins 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCB2 phospholipase C, beta 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA2 plexin A2
POPDC3 popeye domain containing 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRR5 proline rich 5 (renal)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAD51 RAD51 recombinase
RAG1 recombination activating gene 1
RASAL2 RAS protein activator like 2
RFTN1 raftlin, lipid raft linker 1
RNF39 ring finger protein 39
RPAIN RPA interacting protein
RREB1 ras responsive element binding protein 1
S100A9 S100 calcium binding protein A9
SBNO1 strawberry notch homolog 1 (Drosophila)
SIDT2 SID1 transmembrane family, member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC43A3 solute carrier family 43, member 3
SP100 SP100 nuclear antigen
SPON2 spondin 2, extracellular matrix protein
SPPL2B signal peptide peptidase like 2B
SPTBN1 spectrin, beta, non-erythrocytic 1
SSX1 synovial sarcoma, X breakpoint 1
TAOK2 TAO kinase 2
TPMT thiopurine S-methyltransferase
TRIM21 tripartite motif containing 21
UBE2I ubiquitin-conjugating enzyme E2I
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WIPF1 WAS/WASL interacting protein family, member 1
WLS wntless Wnt ligand secretion mediator
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF362 zinc finger protein 362
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM23 ADAM metallopeptidase domain 23
AES amino-terminal enhancer of split
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AMH anti-Mullerian hormone
AMT aminomethyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C11ORF63 chromosome 11 open reading frame 63
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
C8ORF60 chromosome 8 open reading frame 60
CD82 CD82 molecule
CDON cell adhesion associated, oncogene regulated
CLDN15 claudin 15
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNR2 cannabinoid receptor 2 (macrophage)
CXXC4 CXXC finger protein 4
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DACH1 dachshund family transcription factor 1
DYSF dysferlin
EFHD2 EF-hand domain family, member D2
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM46C family with sequence similarity 46, member C
FGL1 fibrinogen-like 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FRK fyn-related Src family tyrosine kinase
FRS2 fibroblast growth factor receptor substrate 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPC3 glypican 3
GPR27 G protein-coupled receptor 27
GSTM2 glutathione S-transferase mu 2 (muscle)
HDAC11 histone deacetylase 11
HIST1H2BN histone cluster 1, H2bn
HOXD11 homeobox D11
HPS6 Hermansky-Pudlak syndrome 6
IFITM1 interferon induced transmembrane protein 1
INPP5J inositol polyphosphate-5-phosphatase J
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD7 potassium channel tetramerization domain containing 7
KLHL12 kelch-like family member 12
KREMEN2 kringle containing transmembrane protein 2
LHX6 LIM homeobox 6
LOC100286895 cell division cycle 27 homolog pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC37A2 leucine rich repeat containing 37, member A2
LY6D lymphocyte antigen 6 complex, locus D
LYRM9 LYR motif containing 9
MBOAT2 membrane bound O-acyltransferase domain containing 2
MRAS muscle RAS oncogene homolog
NACA2 nascent polypeptide-associated complex alpha subunit 2
NAG18 NAG18 mRNA
NKAIN1 Na+/K+ transporting ATPase interacting 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVOL1 ovo-like zinc finger 1
PDE12 phosphodiesterase 12
POLH polymerase (DNA directed), eta
POM121 POM121 transmembrane nucleoporin
PRAF2 PRA1 domain family, member 2
PRR4 proline rich 4 (lacrimal)
RAB30 RAB30, member RAS oncogene family
RBL1 retinoblastoma-like 1
RIBC2 RIB43A domain with coiled-coils 2
RIN2 Ras and Rab interactor 2
RLN1 relaxin 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SAMD9 sterile alpha motif domain containing 9
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC35F5 solute carrier family 35, member F5
SMG9 SMG9 nonsense mediated mRNA decay factor
SOWAHC sosondowah ankyrin repeat domain family member C
SPRR2B small proline-rich protein 2B
SSBP3 single stranded DNA binding protein 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLN1 talin 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
UNC119 unc-119 homolog (C. elegans)
VAX2 ventral anterior homeobox 2
VNN2 vanin 2
XK X-linked Kx blood group
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZNF141 zinc finger protein 141
ZNF35 zinc finger protein 35
ZNF350 zinc finger protein 350
ZNF669 zinc finger protein 669
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747