her2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

224 genes co-occuring with the biological term her2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ADAM10 ADAM metallopeptidase domain 10
ADRB2 adrenoceptor beta 2, surface
AGO2 argonaute RISC catalytic component 2
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AR androgen receptor
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDKRB1 bradykinin receptor B1
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CA9 carbonic anhydrase IX
CAPN1 calpain 1, (mu/I) large subunit
CARM1 coactivator-associated arginine methyltransferase 1
CASC4 cancer susceptibility candidate 4
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CCNA2 cyclin A2
CCND1 cyclin D1
CCND3 cyclin D3
CCNE1 cyclin E1
CCNG2 cyclin G2
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDR2 cerebellar degeneration-related protein 2, 62kDa
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHEK1 checkpoint kinase 1
CMTM5 CKLF-like MARVEL transmembrane domain containing 5
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
DOCK1 dedicator of cytokinesis 1
DPYD dihydropyrimidine dehydrogenase
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
ECD ecdysoneless homolog (Drosophila)
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELK1 ELK1, member of ETS oncogene family
EMP3 epithelial membrane protein 3
ENAH enabled homolog (Drosophila)
EPCAM epithelial cell adhesion molecule
EPHB4 EPH receptor B4
EPOR erythropoietin receptor
EPX eosinophil peroxidase
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV4 ets variant 4
EZR ezrin
F11R F11 receptor
FASN fatty acid synthase
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FHIT fragile histidine triad
FOXM1 forkhead box M1
GATA4 GATA binding protein 4
GLS glutaminase
GLUD1 glutamate dehydrogenase 1
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GPER1 G protein-coupled estrogen receptor 1
H2AFY H2A histone family, member Y
HDAC6 histone deacetylase 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HMGA2 high mobility group AT-hook 2
HOTAIR HOX transcript antisense RNA
HPSE heparanase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL2RG interleukin 2 receptor, gamma
INSL4 insulin-like 4 (placenta)
IQGAP1 IQ motif containing GTPase activating protein 1
IQSEC1 IQ motif and Sec7 domain 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK2 Janus kinase 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT20 keratin 20, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LEP leptin
LEPR leptin receptor
LETMD1 LETM1 domain containing 1
LIN28A lin-28 homolog A (C. elegans)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGEA11 melanoma antigen family A11
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MED1 mediator complex subunit 1
MED23 mediator complex subunit 23
MET MET proto-oncogene, receptor tyrosine kinase
MIR139 microRNA 139
MIR190A microRNA 190a
MIR19A microRNA 19a
MIR200B microRNA 200b
MIR21 microRNA 21
MIR331 microRNA 331
MIR630 microRNA 630
MIR93 microRNA 93
MKI67 marker of proliferation Ki-67
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEK2 NIMA-related kinase 2
NFIB nuclear factor I/B
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH1 notch 1
NOTCH3 notch 3
NRG1 neuregulin 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP1 poly (ADP-ribose) polymerase 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP prolactin-induced protein
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAUR plasminogen activator, urokinase receptor
PLCD1 phospholipase C, delta 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKCA protein kinase C, alpha
PRKCI protein kinase C, iota
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK6 protein tyrosine kinase 6
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PXN paxillin
RAB5A RAB5A, member RAS oncogene family
RAD21 RAD21 homolog (S. pombe)
RAG2 recombination activating gene 2
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
S100A14 S100 calcium binding protein A14
S1PR4 sphingosine-1-phosphate receptor 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STARD10 StAR-related lipid transfer (START) domain containing 10
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TERT telomerase reverse transcriptase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFB1 transforming growth factor, beta 1
THEMIS2 thymocyte selection associated family member 2
TK1 thymidine kinase 1, soluble
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBB3 tubulin, beta 3 class III
TYMS thymidylate synthetase
UROD uroporphyrinogen decarboxylase
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
VIPR1 vasoactive intestinal peptide receptor 1
WNT10B wingless-type MMTV integration site family, member 10B
WWOX WW domain containing oxidoreductase
WWP1 WW domain containing E3 ubiquitin protein ligase 1
YBX1 Y box binding protein 1