hereditary breast ovarian cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An autosomal dominant disease characterized by the higher than normal tendency to develop breast and ovarian cancers in genetically related families. (Human Disease Ontology, DOID_5683)
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25 genes co-occuring with the disease hereditary breast ovarian cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
BRCA1 breast cancer 1, early onset 2.41601
BRCA2 breast cancer 2, early onset 2.23832
MAMSTR MEF2 activating motif and SAP domain containing transcriptional regulator 1.20829
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.0303
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.964148
INSC inscuteable homolog (Drosophila) 0.951604
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.871643
TP53 tumor protein p53 0.822897
MLH1 mutL homolog 1 0.751678
MSH2 mutS homolog 2 0.711183
MSH6 mutS homolog 6 0.658818
IGFBP4 insulin-like growth factor binding protein 4 0.557897
PRSS1 protease, serine, 1 (trypsin 1) 0.554403
RAD51C RAD51 paralog C 0.480186
BARD1 BRCA1 associated RING domain 1 0.431144
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.400826
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.394491
BMPR1A bone morphogenetic protein receptor, type IA 0.383708
PALB2 partner and localizer of BRCA2 0.345675
CDKN2A cyclin-dependent kinase inhibitor 2A 0.307033
NME1-NME2 NME1-NME2 readthrough 0.301615
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.233878
CHEK2 checkpoint kinase 2 0.22454
GADD45A growth arrest and DNA-damage-inducible, alpha 0.200006
ATM ATM serine/threonine kinase 0.178126