heroin dependence Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An opiate dependence that involves the continued use of heroin despite problems related to use of the substance. (Human Disease Ontology, DOID_9976)
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Genes

27 genes associated with the disease heroin dependence in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
BDNF brain-derived neurotrophic factor
COMT catechol-O-methyltransferase
CRY1 cryptochrome circadian clock 1
CSNK1E casein kinase 1, epsilon
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DUSP27 dual specificity phosphatase 27 (putative)
GAL galanin/GMAP prepropeptide
GRM6 glutamate receptor, metabotropic 6
GRM8 glutamate receptor, metabotropic 8
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
MAOA monoamine oxidase A
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
PDYN prodynorphin
RIMS2 regulating synaptic membrane exocytosis 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
XIRP2 xin actin binding repeat containing 2