heroin dependence Gene Set
| Dataset |
GAD Gene-Disease Associations
|
| Category |
disease or phenotype associations
|
| Type |
disease |
| Description |
An opiate dependence that involves the continued use of heroin despite problems related to use of the substance. (Human Disease Ontology, DOID_9976)
|
| Similar Terms |
|
| Downloads & Tools |
|
Genes
27 genes associated with the disease heroin dependence in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
| Symbol |
Name |
|
ABCB1
|
ATP-binding cassette, sub-family B (MDR/TAP), member 1
|
|
BDNF
|
brain-derived neurotrophic factor
|
|
COMT
|
catechol-O-methyltransferase
|
|
CRY1
|
cryptochrome circadian clock 1
|
|
CSNK1E
|
casein kinase 1, epsilon
|
|
DRD1
|
dopamine receptor D1
|
|
DRD2
|
dopamine receptor D2
|
|
DRD4
|
dopamine receptor D4
|
|
DUSP27
|
dual specificity phosphatase 27 (putative)
|
|
GAL
|
galanin/GMAP prepropeptide
|
|
GRM6
|
glutamate receptor, metabotropic 6
|
|
GRM8
|
glutamate receptor, metabotropic 8
|
|
HTR2A
|
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
|
|
HTR3B
|
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
|
|
MAOA
|
monoamine oxidase A
|
|
MC2R
|
melanocortin 2 receptor (adrenocorticotropic hormone)
|
|
NR4A2
|
nuclear receptor subfamily 4, group A, member 2
|
|
OPRD1
|
opioid receptor, delta 1
|
|
OPRK1
|
opioid receptor, kappa 1
|
|
OPRM1
|
opioid receptor, mu 1
|
|
PDYN
|
prodynorphin
|
|
RIMS2
|
regulating synaptic membrane exocytosis 2
|
|
SLC6A3
|
solute carrier family 6 (neurotransmitter transporter), member 3
|
|
SLC6A4
|
solute carrier family 6 (neurotransmitter transporter), member 4
|
|
TPH1
|
tryptophan hydroxylase 1
|
|
TPH2
|
tryptophan hydroxylase 2
|
|
XIRP2
|
xin actin binding repeat containing 2
|
