hesperetin-1531 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the hesperetin-1531 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADTRP androgen-dependent TFPI-regulating protein
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AIM2 absent in melanoma 2
AK1 adenylate kinase 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMT aminomethyltransferase
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC132 coiled-coil domain containing 132
CCR9 chemokine (C-C motif) receptor 9
CDC25A cell division cycle 25A
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CENPO centromere protein O
CHRM3 cholinergic receptor, muscarinic 3
CLSPN claspin
COL17A1 collagen, type XVII, alpha 1
CRMP1 collapsin response mediator protein 1
CROCC ciliary rootlet coiled-coil, rootletin
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCAF4 DDB1 and CUL4 associated factor 4
DHRS12 dehydrogenase/reductase (SDR family) member 12
DMTN dematin actin binding protein
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
ECE1 endothelin converting enzyme 1
EFNB3 ephrin-B3
ELOVL5 ELOVL fatty acid elongase 5
EPS8L1 EPS8-like 1
EPX eosinophil peroxidase
FBXO2 F-box protein 2
FKBP15 FK506 binding protein 15, 133kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLOT1 flotillin 1
FST follistatin
GJA8 gap junction protein, alpha 8, 50kDa
HCFC1 host cell factor C1
HOXC8 homeobox C8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL20RA interleukin 20 receptor, alpha
IL6ST interleukin 6 signal transducer
ISG20 interferon stimulated exonuclease gene 20kDa
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLF3 Kruppel-like factor 3 (basic)
KPTN kaptin (actin binding protein)
LPXN leupaxin
LRP5L low density lipoprotein receptor-related protein 5-like
MAGEA1 melanoma antigen family A1
MARK4 MAP/microtubule affinity-regulating kinase 4
MFAP3L microfibrillar-associated protein 3-like
MSL3 male-specific lethal 3 homolog (Drosophila)
MST1 macrophage stimulating 1
MTA1 metastasis associated 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB13 protocadherin beta 13
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS14 regulator of G-protein signaling 14
RPL10 ribosomal protein L10
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC24D SEC24 family member D
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SP110 SP110 nuclear body protein
SYNE1 spectrin repeat containing, nuclear envelope 1
TAOK2 TAO kinase 2
TBX10 T-box 10
THSD4 thrombospondin, type I, domain containing 4
TJAP1 tight junction associated protein 1 (peripheral)
TTC28 tetratricopeptide repeat domain 28
USF2 upstream transcription factor 2, c-fos interacting
YIPF2 Yip1 domain family, member 2
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF358 zinc finger protein 358
ZNF551 zinc finger protein 551
ZNF573 zinc finger protein 573
ZNF750 zinc finger protein 750
ZNF79 zinc finger protein 79
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOLD1 apolipoprotein L domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARID4A AT rich interactive domain 4A (RBP1-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C10ORF88 chromosome 10 open reading frame 88
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CBX4 chromobox homolog 4
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK3 cyclin-dependent kinase 3
CFD complement factor D (adipsin)
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CSPP1 centrosome and spindle pole associated protein 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELOVL4 ELOVL fatty acid elongase 4
EPHA2 EPH receptor A2
EPPK1 epiplakin 1
ETNK2 ethanolamine kinase 2
FBXO46 F-box protein 46
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP10 FK506 binding protein 10, 65 kDa
GBP2 guanylate binding protein 2, interferon-inducible
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPC4 glypican 4
GTPBP2 GTP binding protein 2
GTPBP6 GTP binding protein 6 (putative)
HDAC5 histone deacetylase 5
HIST1H2AJ histone cluster 1, H2aj
HOOK1 hook microtubule-tethering protein 1
HOXC10 homeobox C10
IPO8 importin 8
KCTD20 potassium channel tetramerization domain containing 20
KLC2 kinesin light chain 2
LIG4 ligase IV, DNA, ATP-dependent
LOC100287590 uncharacterized LOC100287590
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
METTL21B methyltransferase like 21B
MRPL52 mitochondrial ribosomal protein L52
MTA2 metastasis associated 1 family, member 2
NDE1 nudE neurodevelopment protein 1
NKRF NFKB repressing factor
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PDZRN3 PDZ domain containing ring finger 3
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PODXL2 podocalyxin-like 2
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRR14L proline rich 14-like
RAB30 RAB30, member RAS oncogene family
RBL1 retinoblastoma-like 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF121 ring finger protein 121
RNF2 ring finger protein 2
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC3 syndecan 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD1A SET domain containing 1A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2B3 SH2B adaptor protein 3
SLC12A9 solute carrier family 12, member 9
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX12 SRY (sex determining region Y)-box 12
SPATA7 spermatogenesis associated 7
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TFF2 trefoil factor 2
THRAP3 thyroid hormone receptor associated protein 3
TMC5 transmembrane channel-like 5
TMEM180 transmembrane protein 180
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TOM1 target of myb1 (chicken)
TPCN1 two pore segment channel 1
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
ULBP2 UL16 binding protein 2
WDR62 WD repeat domain 62
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF184 zinc finger protein 184
ZNF250 zinc finger protein 250
ZNF286A zinc finger protein 286A
ZNF329 zinc finger protein 329
ZNF492 zinc finger protein 492
ZNF574 zinc finger protein 574
ZNF76 zinc finger protein 76