hesperetin-1947 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the hesperetin-1947 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY3 adenylate cyclase 3
ADORA1 adenosine A1 receptor
ANKRD40 ankyrin repeat domain 40
APLP2 amyloid beta (A4) precursor-like protein 2
APOC1 apolipoprotein C-I
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATF6B activating transcription factor 6 beta
ATM ATM serine/threonine kinase
ATXN7L3B ataxin 7-like 3B
AVPR1B arginine vasopressin receptor 1B
BCL9 B-cell CLL/lymphoma 9
BLVRA biliverdin reductase A
C7ORF43 chromosome 7 open reading frame 43
CALML4 calmodulin-like 4
CAPRIN1 cell cycle associated protein 1
CD24 CD24 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHML choroideremia-like (Rab escort protein 2)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CIZ1 CDKN1A interacting zinc finger protein 1
COPS7B COP9 signalosome subunit 7B
CRY2 cryptochrome circadian clock 2
CSNK1D casein kinase 1, delta
CTC1 CTS telomere maintenance complex component 1
CYB561 cytochrome b561
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DTNA dystrobrevin, alpha
E2F5 E2F transcription factor 5, p130-binding
EFNA1 ephrin-A1
ERCC2 excision repair cross-complementation group 2
FGF5 fibroblast growth factor 5
FUBP1 far upstream element (FUSE) binding protein 1
GALK2 galactokinase 2
GALR3 galanin receptor 3
GEMIN4 gem (nuclear organelle) associated protein 4
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GSN gelsolin
HDAC5 histone deacetylase 5
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HUS1 HUS1 checkpoint homolog (S. pombe)
IDO1 indoleamine 2,3-dioxygenase 1
IL13RA1 interleukin 13 receptor, alpha 1
ITFG1 integrin alpha FG-GAP repeat containing 1
ITM2C integral membrane protein 2C
KIFC1 kinesin family member C1
KLHL23 kelch-like family member 23
KRIT1 KRIT1, ankyrin repeat containing
LMF1 lipase maturation factor 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
MECP2 methyl CpG binding protein 2
MICALL1 MICAL-like 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAV2 neuron navigator 2
NCOA3 nuclear receptor coactivator 3
NKIRAS2 NFKB inhibitor interacting Ras-like 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PABPN1 poly(A) binding protein, nuclear 1
PARVA parvin, alpha
PEX10 peroxisomal biogenesis factor 10
PEX5 peroxisomal biogenesis factor 5
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKP2 plakophilin 2
PLSCR3 phospholipid scramblase 3
PLXND1 plexin D1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
R3HDM4 R3H domain containing 4
RAB11B RAB11B, member RAS oncogene family
RAB14 RAB14, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RNF167 ring finger protein 167
RUSC2 RUN and SH3 domain containing 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIRT6 sirtuin 6
SOX13 SRY (sex determining region Y)-box 13
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRSF7 serine/arginine-rich splicing factor 7
STK16 serine/threonine kinase 16
SUGP1 SURP and G patch domain containing 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TBRG4 transforming growth factor beta regulator 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TOR4A torsin family 4, member A
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
VAC14 Vac14 homolog (S. cerevisiae)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR19 WD repeat domain 19
WNT7A wingless-type MMTV integration site family, member 7A
WRAP53 WD repeat containing, antisense to TP53
ZBTB25 zinc finger and BTB domain containing 25
ZMAT5 zinc finger, matrin-type 5
ZNF354A zinc finger protein 354A
ZNF821 zinc finger protein 821
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ABT1 activator of basal transcription 1
ADAM15 ADAM metallopeptidase domain 15
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANXA2P3 annexin A2 pseudogene 3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARGLU1 arginine and glutamate rich 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAHD1 bromo adjacent homology domain containing 1
BEX1 brain expressed, X-linked 1
C17ORF85 chromosome 17 open reading frame 85
C6ORF47 chromosome 6 open reading frame 47
CCND3 cyclin D3
CD53 CD53 molecule
CEP170B centrosomal protein 170B
CFAP74 cilia and flagella associated protein 74
CIDEC cell death-inducing DFFA-like effector c
CLDN14 claudin 14
CNTD2 cyclin N-terminal domain containing 2
CTAGE9 CTAGE family, member 9
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
ERMP1 endoplasmic reticulum metallopeptidase 1
ESM1 endothelial cell-specific molecule 1
EXTL2 exostosin-like glycosyltransferase 2
FAM102A family with sequence similarity 102, member A
FAM114A2 family with sequence similarity 114, member A2
FAM192A family with sequence similarity 192, member A
FANCC Fanconi anemia, complementation group C
FBXW12 F-box and WD repeat domain containing 12
FBXW4 F-box and WD repeat domain containing 4
FOXA1 forkhead box A1
FURIN furin (paired basic amino acid cleaving enzyme)
FZD4 frizzled class receptor 4
GATA6 GATA binding protein 6
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPRC5D G protein-coupled receptor, class C, group 5, member D
GPX2 glutathione peroxidase 2
GRM6 glutamate receptor, metabotropic 6
HAGH hydroxyacylglutathione hydrolase
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIST1H2AJ histone cluster 1, H2aj
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA4L heat shock 70kDa protein 4-like
IFNA17 interferon, alpha 17
IRF9 interferon regulatory factor 9
ISCU iron-sulfur cluster assembly enzyme
JMJD4 jumonji domain containing 4
KIF13B kinesin family member 13B
KIF20B kinesin family member 20B
KLC2 kinesin light chain 2
KLHL21 kelch-like family member 21
MECR mitochondrial trans-2-enoyl-CoA reductase
MRPL28 mitochondrial ribosomal protein L28
MRPS34 mitochondrial ribosomal protein S34
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NSUN3 NOP2/Sun domain family, member 3
NT5E 5'-nucleotidase, ecto (CD73)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PCNXL4 pecanex-like 4 (Drosophila)
PELP1 proline, glutamate and leucine rich protein 1
PHACTR4 phosphatase and actin regulator 4
PHGDH phosphoglycerate dehydrogenase
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB17 RAB17, member RAS oncogene family
RPL23AP32 ribosomal protein L23a pseudogene 32
RRP1 ribosomal RNA processing 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SFXN1 sideroflexin 1
SH3GL1 SH3-domain GRB2-like 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SPAG1 sperm associated antigen 1
STRN4 striatin, calmodulin binding protein 4
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THEM6 thioesterase superfamily member 6
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMED3 transmembrane emp24 protein transport domain containing 3
TMEM260 transmembrane protein 260
TOLLIP toll interacting protein
TPCN1 two pore segment channel 1
TRIM45 tripartite motif containing 45
TSPAN32 tetraspanin 32
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR13 WD repeat domain 13
ZBTB11 zinc finger and BTB domain containing 11
ZCCHC10 zinc finger, CCHC domain containing 10
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF175 zinc finger protein 175