hesperetin-2031 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the hesperetin-2031 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
AQP9 aquaporin 9
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAIAP2 BAI1-associated protein 2
BLVRB biliverdin reductase B
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C1ORF159 chromosome 1 open reading frame 159
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF24 chromosome 22 open reading frame 24
CA5BP1 carbonic anhydrase VB pseudogene 1
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL4 chemokine (C-C motif) ligand 4
CD300A CD300a molecule
CD70 CD70 molecule
CDH22 cadherin 22, type 2
CETN1 centrin, EF-hand protein, 1
CLEC4M C-type lectin domain family 4, member M
CLIP1 CAP-GLY domain containing linker protein 1
COPS2 COP9 signalosome subunit 2
CRY2 cryptochrome circadian clock 2
DLG3 discs, large homolog 3 (Drosophila)
ELMO2 engulfment and cell motility 2
EPHB6 EPH receptor B6
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPX eosinophil peroxidase
FAM134B family with sequence similarity 134, member B
FGFBP1 fibroblast growth factor binding protein 1
FHL1 four and a half LIM domains 1
G6PC3 glucose 6 phosphatase, catalytic, 3
GBP2 guanylate binding protein 2, interferon-inducible
GCAT glycine C-acetyltransferase
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IGF1R insulin-like growth factor 1 receptor
IGSF1 immunoglobulin superfamily, member 1
IL18 interleukin 18
IRF7 interferon regulatory factor 7
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIZ kizuna centrosomal protein
KLF6 Kruppel-like factor 6
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LTB4R leukotriene B4 receptor
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MASP2 mannan-binding lectin serine peptidase 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEF2D myocyte enhancer factor 2D
MFSD11 major facilitator superfamily domain containing 11
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MOB3B MOB kinase activator 3B
MSH3 mutS homolog 3
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
MVK mevalonate kinase
MYO9B myosin IXB
NAT6 N-acetyltransferase 6 (GCN5-related)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NQO1 NAD(P)H dehydrogenase, quinone 1
OCRL oculocerebrorenal syndrome of Lowe
PCIF1 PDX1 C-terminal inhibiting factor 1
PKP3 plakophilin 3
PLCD1 phospholipase C, delta 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RGS1 regulator of G-protein signaling 1
RHOQ ras homolog family member Q
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
SEC61B Sec61 beta subunit
SIK2 salt-inducible kinase 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
STAC SH3 and cysteine rich domain
SUGP1 SURP and G patch domain containing 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM156 transmembrane protein 156
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNNT2 troponin T type 2 (cardiac)
TRAC T cell receptor alpha constant
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
TRIP11 thyroid hormone receptor interactor 11
TTLL4 tubulin tyrosine ligase-like family member 4
VAC14 Vac14 homolog (S. cerevisiae)
WARS tryptophanyl-tRNA synthetase
WDR13 WD repeat domain 13
YLPM1 YLP motif containing 1
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF133 zinc finger protein 133

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ABT1 activator of basal transcription 1
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADAT1 adenosine deaminase, tRNA-specific 1
AGPS alkylglycerone phosphate synthase
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APIP APAF1 interacting protein
AQP2 aquaporin 2 (collecting duct)
ARHGAP10 Rho GTPase activating protein 10
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD2B ATPase family, AAA domain containing 2B
ATF7IP2 activating transcription factor 7 interacting protein 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
CARD9 caspase recruitment domain family, member 9
CASP3 caspase 3, apoptosis-related cysteine peptidase
CD244 CD244 molecule, natural killer cell receptor 2B4
CD320 CD320 molecule
CLP1 cleavage and polyadenylation factor I subunit 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNR2 cannabinoid receptor 2 (macrophage)
CRYL1 crystallin, lambda 1
CSRNP2 cysteine-serine-rich nuclear protein 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DBF4 DBF4 zinc finger
DCTN6 dynactin 6
DDB2 damage-specific DNA binding protein 2, 48kDa
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DYSF dysferlin
ERO1L ERO1-like (S. cerevisiae)
FAM63A family with sequence similarity 63, member A
FANCF Fanconi anemia, complementation group F
FMO4 flavin containing monooxygenase 4
FOXM1 forkhead box M1
FUCA1 fucosidase, alpha-L- 1, tissue
GAB2 GRB2-associated binding protein 2
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIMAP6 GTPase, IMAP family member 6
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR183 G protein-coupled receptor 183
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HIST3H2A histone cluster 3, H2a
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KIF18A kinesin family member 18A
KRI1 KRI1 homolog (S. cerevisiae)
LAMP5 lysosomal-associated membrane protein family, member 5
LPAR6 lysophosphatidic acid receptor 6
LXN latexin
MAEA macrophage erythroblast attacher
MAPK3 mitogen-activated protein kinase 3
MEST mesoderm specific transcript
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIS18A MIS18 kinetochore protein A
MTMR11 myotubularin related protein 11
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCKAP1L NCK-associated protein 1-like
NME6 NME/NM23 nucleoside diphosphate kinase 6
NNT nicotinamide nucleotide transhydrogenase
OARD1 O-acyl-ADP-ribose deacylase 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PEMT phosphatidylethanolamine N-methyltransferase
PEX26 peroxisomal biogenesis factor 26
PISD phosphatidylserine decarboxylase
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POU2F1 POU class 2 homeobox 1
PPIEL peptidylprolyl isomerase E-like pseudogene
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
QPRT quinolinate phosphoribosyltransferase
RAB1B RAB1B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RARS arginyl-tRNA synthetase
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF220 ring finger protein 220
RPAP1 RNA polymerase II associated protein 1
RPIA ribose 5-phosphate isomerase A
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RSF1 remodeling and spacing factor 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC25A46 solute carrier family 25, member 46
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPON2 spondin 2, extracellular matrix protein
SSFA2 sperm specific antigen 2
STK25 serine/threonine kinase 25
STX18 syntaxin 18
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TIPIN TIMELESS interacting protein
TTC17 tetratricopeptide repeat domain 17
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
URM1 ubiquitin related modifier 1
XKR8 XK, Kell blood group complex subunit-related family, member 8