| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the hesperetin-5350 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| AHI1 | Abelson helper integration site 1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| APOE | apolipoprotein E |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CASKIN2 | CASK interacting protein 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC9 | coiled-coil domain containing 9 |
| CES3 | carboxylesterase 3 |
| CLASRP | CLK4-associating serine/arginine rich protein |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DDO | D-aspartate oxidase |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EXOC7 | exocyst complex component 7 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLJ42627 | uncharacterized LOC645644 |
| GFER | growth factor, augmenter of liver regeneration |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GRB10 | growth factor receptor-bound protein 10 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HOXA4 | homeobox A4 |
| IL4R | interleukin 4 receptor |
| INHBA | inhibin, beta A |
| IRF6 | interferon regulatory factor 6 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM6B | lysine (K)-specific demethylase 6B |
| KIF1C | kinesin family member 1C |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAP4 | microtubule-associated protein 4 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEG3 | maternally expressed 3 (non-protein coding) |
| METTL7A | methyltransferase like 7A |
| MST1 | macrophage stimulating 1 |
| MYO9B | myosin IXB |
| NBEAL2 | neurobeachin-like 2 |
| NCDN | neurochondrin |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAPOLA | poly(A) polymerase alpha |
| PDAP1 | PDGFA associated protein 1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PER1 | period circadian clock 1 |
| PITX1 | paired-like homeodomain 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PRMT2 | protein arginine methyltransferase 2 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SDS | serine dehydratase |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIK2 | salt-inducible kinase 2 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SMTN | smoothelin |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRR2B | small proline-rich protein 2B |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM31 | tripartite motif containing 31 |
| TTC9 | tetratricopeptide repeat domain 9 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP36 | ubiquitin specific peptidase 36 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZNF133 | zinc finger protein 133 |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CDC37 | cell division cycle 37 |
| CDC73 | cell division cycle 73 |
| CENPQ | centromere protein Q |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLDND1 | claudin domain containing 1 |
| COCH | cochlin |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CUEDC1 | CUE domain containing 1 |
| CUL2 | cullin 2 |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 |
| DSE | dermatan sulfate epimerase |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| ERF | Ets2 repressor factor |
| EXOC5 | exocyst complex component 5 |
| FUZ | fuzzy planar cell polarity protein |
| FZD3 | frizzled class receptor 3 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GHR | growth hormone receptor |
| GLMN | glomulin, FKBP associated protein |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GTF2I | general transcription factor IIi |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| H1F0 | H1 histone family, member 0 |
| HMGB3 | high mobility group box 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRF2 | interferon regulatory factor 2 |
| ISG15 | ISG15 ubiquitin-like modifier |
| LEMD3 | LEM domain containing 3 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMAN2L | lectin, mannose-binding 2-like |
| LMNB1 | lamin B1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAPK3 | mitogen-activated protein kinase 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEIS1 | Meis homeobox 1 |
| MEIS2 | Meis homeobox 2 |
| MIS12 | MIS12 kinetochore complex component |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MXD3 | MAX dimerization protein 3 |
| MXRA7 | matrix-remodelling associated 7 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma |
| NARFL | nuclear prelamin A recognition factor-like |
| NCAPD3 | non-SMC condensin II complex, subunit D3 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NFS1 | NFS1 cysteine desulfurase |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NMU | neuromedin U |
| NSF | N-ethylmaleimide-sensitive factor |
| OXR1 | oxidation resistance 1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PCTP | phosphatidylcholine transfer protein |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PRR3 | proline rich 3 |
| PSENEN | presenilin enhancer gamma secretase subunit |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM42 | RNA binding motif protein 42 |
| RCOR3 | REST corepressor 3 |
| REEP1 | receptor accessory protein 1 |
| RHOC | ras homolog family member C |
| RIT1 | Ras-like without CAAX 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2B3 | SH2B adaptor protein 3 |
| SHROOM2 | shroom family member 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| STBD1 | starch binding domain 1 |
| STK16 | serine/threonine kinase 16 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TMEM33 | transmembrane protein 33 |
| TMEM38B | transmembrane protein 38B |
| TMEM57 | transmembrane protein 57 |
| TTF2 | transcription termination factor, RNA polymerase II |
| UBA3 | ubiquitin-like modifier activating enzyme 3 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF211 | zinc finger protein 211 |