hesperetin-5350 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the hesperetin-5350 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AHI1 Abelson helper integration site 1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOE apolipoprotein E
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARID1A AT rich interactive domain 1A (SWI-like)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C21ORF2 chromosome 21 open reading frame 2
CASKIN2 CASK interacting protein 2
CCDC85C coiled-coil domain containing 85C
CCDC9 coiled-coil domain containing 9
CES3 carboxylesterase 3
CLASRP CLK4-associating serine/arginine rich protein
COPZ2 coatomer protein complex, subunit zeta 2
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDO D-aspartate oxidase
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EXOC7 exocyst complex component 7
FGFR2 fibroblast growth factor receptor 2
FLJ42627 uncharacterized LOC645644
GFER growth factor, augmenter of liver regeneration
GJA4 gap junction protein, alpha 4, 37kDa
GJB3 gap junction protein, beta 3, 31kDa
GRB10 growth factor receptor-bound protein 10
HEXA hexosaminidase A (alpha polypeptide)
HOXA4 homeobox A4
IL4R interleukin 4 receptor
INHBA inhibin, beta A
IRF6 interferon regulatory factor 6
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM6B lysine (K)-specific demethylase 6B
KIF1C kinesin family member 1C
KRIT1 KRIT1, ankyrin repeat containing
LARP7 La ribonucleoprotein domain family, member 7
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAP4 microtubule-associated protein 4
MAPK11 mitogen-activated protein kinase 11
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEG3 maternally expressed 3 (non-protein coding)
METTL7A methyltransferase like 7A
MST1 macrophage stimulating 1
MYO9B myosin IXB
NBEAL2 neurobeachin-like 2
NCDN neurochondrin
NCR2 natural cytotoxicity triggering receptor 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGIN1 oxidative stress induced growth inhibitor 1
PAPOLA poly(A) polymerase alpha
PDAP1 PDGFA associated protein 1
PDLIM5 PDZ and LIM domain 5
PER1 period circadian clock 1
PITX1 paired-like homeodomain 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRMT2 protein arginine methyltransferase 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAD23B RAD23 homolog B (S. cerevisiae)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SDS serine dehydratase
SEC14L1 SEC14-like 1 (S. cerevisiae)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIK2 salt-inducible kinase 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIVA1 SIVA1, apoptosis-inducing factor
SLC12A8 solute carrier family 12, member 8
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLMO1 slowmo homolog 1 (Drosophila)
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMG6 SMG6 nonsense mediated mRNA decay factor
SMTN smoothelin
SOGA1 suppressor of glucose, autophagy associated 1
SOX9 SRY (sex determining region Y)-box 9
SPRR2B small proline-rich protein 2B
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRCAP Snf2-related CREBBP activator protein
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TRAK1 trafficking protein, kinesin binding 1
TRIM31 tripartite motif containing 31
TTC9 tetratricopeptide repeat domain 9
USF2 upstream transcription factor 2, c-fos interacting
USP36 ubiquitin specific peptidase 36
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBTB43 zinc finger and BTB domain containing 43
ZNF133 zinc finger protein 133
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACADSB acyl-CoA dehydrogenase, short/branched chain
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBS1 Bardet-Biedl syndrome 1
BCAS4 breast carcinoma amplified sequence 4
BIK BCL2-interacting killer (apoptosis-inducing)
C21ORF91 chromosome 21 open reading frame 91
C2ORF44 chromosome 2 open reading frame 44
CDC37 cell division cycle 37
CDC73 cell division cycle 73
CENPQ centromere protein Q
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLASP1 cytoplasmic linker associated protein 1
CLDND1 claudin domain containing 1
COCH cochlin
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CUEDC1 CUE domain containing 1
CUL2 cullin 2
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16
DSE dermatan sulfate epimerase
EFHC1 EF-hand domain (C-terminal) containing 1
ERF Ets2 repressor factor
EXOC5 exocyst complex component 5
FUZ fuzzy planar cell polarity protein
FZD3 frizzled class receptor 3
GCA grancalcin, EF-hand calcium binding protein
GHR growth hormone receptor
GLMN glomulin, FKBP associated protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2I general transcription factor IIi
GUF1 GUF1 GTPase homolog (S. cerevisiae)
H1F0 H1 histone family, member 0
HMGB3 high mobility group box 3
IFI6 interferon, alpha-inducible protein 6
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2 interferon regulatory factor 2
ISG15 ISG15 ubiquitin-like modifier
LEMD3 LEM domain containing 3
LGALS1 lectin, galactoside-binding, soluble, 1
LINC00115 long intergenic non-protein coding RNA 115
LMAN2L lectin, mannose-binding 2-like
LMNB1 lamin B1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK3 mitogen-activated protein kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MIS12 MIS12 kinetochore complex component
MKNK2 MAP kinase interacting serine/threonine kinase 2
MUM1 melanoma associated antigen (mutated) 1
MXD3 MAX dimerization protein 3
MXRA7 matrix-remodelling associated 7
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NARFL nuclear prelamin A recognition factor-like
NCAPD3 non-SMC condensin II complex, subunit D3
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NFS1 NFS1 cysteine desulfurase
NHEJ1 nonhomologous end-joining factor 1
NMU neuromedin U
NSF N-ethylmaleimide-sensitive factor
OXR1 oxidation resistance 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCTP phosphatidylcholine transfer protein
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PRR3 proline rich 3
PSENEN presenilin enhancer gamma secretase subunit
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM42 RNA binding motif protein 42
RCOR3 REST corepressor 3
REEP1 receptor accessory protein 1
RHOC ras homolog family member C
RIT1 Ras-like without CAAX 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SETD8 SET domain containing (lysine methyltransferase) 8
SH2B3 SH2B adaptor protein 3
SHROOM2 shroom family member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TCEAL1 transcription elongation factor A (SII)-like 1
TMEM33 transmembrane protein 33
TMEM38B transmembrane protein 38B
TMEM57 transmembrane protein 57
TTF2 transcription termination factor, RNA polymerase II
UBA3 ubiquitin-like modifier activating enzyme 3
UBE2S ubiquitin-conjugating enzyme E2S
VAV1 vav 1 guanine nucleotide exchange factor
VCPKMT valosin containing protein lysine (K) methyltransferase
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBED8 zinc finger, BED-type containing 8
ZMAT5 zinc finger, matrin-type 5
ZNF211 zinc finger protein 211