hesperidin-6714 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the hesperidin-6714 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACO2 aconitase 2, mitochondrial
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTN2 actinin, alpha 2
ALOX5 arachidonate 5-lipoxygenase
ANGPTL2 angiopoietin-like 2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BAIAP3 BAI1-associated protein 3
BTF3P11 basic transcription factor 3 pseudogene 11
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CARTPT CART prepropeptide
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD6 CD6 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLEC7A C-type lectin domain family 7, member A
CLIC5 chloride intracellular channel 5
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CPN2 carboxypeptidase N, polypeptide 2
CRTAC1 cartilage acidic protein 1
CSF1 colony stimulating factor 1 (macrophage)
CST1 cystatin SN
CTNND2 catenin (cadherin-associated protein), delta 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCLK2 doublecortin-like kinase 2
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DLC1 DLC1 Rho GTPase activating protein
DRD2 dopamine receptor D2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FGF18 fibroblast growth factor 18
FLT3LG fms-related tyrosine kinase 3 ligand
FOXF1 forkhead box F1
GALR2 galanin receptor 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HRG histidine-rich glycoprotein
IFNA6 interferon, alpha 6
ITGA7 integrin, alpha 7
ITGB6 integrin, beta 6
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KERA keratocan
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLHDC8A kelch domain containing 8A
KRT19P2 keratin 19 pseudogene 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LINC00216 long intergenic non-protein coding RNA 216
LRMP lymphoid-restricted membrane protein
MED25 mediator complex subunit 25
MEG3 maternally expressed 3 (non-protein coding)
MMP10 matrix metallopeptidase 10
MMP3 matrix metallopeptidase 3
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
N4BP2L1 NEDD4 binding protein 2-like 1
OASL 2'-5'-oligoadenylate synthetase-like
PAX2 paired box 2
PAX8 paired box 8
PCDHB3 protocadherin beta 3
PHF7 PHD finger protein 7
PNMAL1 paraneoplastic Ma antigen family-like 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRAMEF11 PRAME family member 11
PRM2 protamine 2
RASAL2 RAS protein activator like 2
RBBP9 retinoblastoma binding protein 9
RCE1 Ras converting CAAX endopeptidase 1
REEP1 receptor accessory protein 1
RPS3A ribosomal protein S3A
RUNX1 runt-related transcription factor 1
S1PR1 sphingosine-1-phosphate receptor 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SMAD1 SMAD family member 1
SOD2 superoxide dismutase 2, mitochondrial
SPRR2B small proline-rich protein 2B
SRRT serrate, RNA effector molecule
SYT12 synaptotagmin XII
TAAR5 trace amine associated receptor 5
TACR1 tachykinin receptor 1
TAS2R13 taste receptor, type 2, member 13
TLR4 toll-like receptor 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNK2 tyrosine kinase, non-receptor, 2
TOX thymocyte selection-associated high mobility group box
TRIM3 tripartite motif containing 3
UBE2D1 ubiquitin-conjugating enzyme E2D 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WISP2 WNT1 inducible signaling pathway protein 2
ZNF117 zinc finger protein 117
ZNF268 zinc finger protein 268
ZNF556 zinc finger protein 556

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACAD8 acyl-CoA dehydrogenase family, member 8
ADAM15 ADAM metallopeptidase domain 15
ADAT1 adenosine deaminase, tRNA-specific 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BEX4 brain expressed, X-linked 4
BGLAP bone gamma-carboxyglutamate (gla) protein
C17ORF70 chromosome 17 open reading frame 70
C17ORF80 chromosome 17 open reading frame 80
C1ORF54 chromosome 1 open reading frame 54
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBX8 chromobox homolog 8
CCNJ cyclin J
CD9 CD9 molecule
CDC37L1 cell division cycle 37-like 1
CDH7 cadherin 7, type 2
CEP85 centrosomal protein 85kDa
CHM choroideremia (Rab escort protein 1)
CHMP1B charged multivesicular body protein 1B
CLCN6 chloride channel, voltage-sensitive 6
CLDN4 claudin 4
CORO1A coronin, actin binding protein, 1A
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCP1A decapping mRNA 1A
DTX4 deltex 4, E3 ubiquitin ligase
DUSP8 dual specificity phosphatase 8
EAF2 ELL associated factor 2
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EXOC5 exocyst complex component 5
FBXL7 F-box and leucine-rich repeat protein 7
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FKBP5 FK506 binding protein 5
FNTB farnesyltransferase, CAAX box, beta
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GLT8D2 glycosyltransferase 8 domain containing 2
GTF2I general transcription factor IIi
H2BFS H2B histone family, member S (pseudogene)
HDAC5 histone deacetylase 5
HELZ helicase with zinc finger
HIST1H2AM histone cluster 1, H2am
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA1L heat shock 70kDa protein 1-like
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFNAR1 interferon (alpha, beta and omega) receptor 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
KRT4 keratin 4, type II
KRT75 keratin 75, type II
KRT8P12 keratin 8 pseudogene 12
LOC100127972 uncharacterized LOC100127972
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGEH1 melanoma antigen family H1
MANBA mannosidase, beta A, lysosomal
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
MFSD6 major facilitator superfamily domain containing 6
MITF microphthalmia-associated transcription factor
MOSPD3 motile sperm domain containing 3
NDRG4 NDRG family member 4
NUPR1 nuclear protein, transcriptional regulator, 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OLFML3 olfactomedin-like 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAIP2B poly(A) binding protein interacting protein 2B
PDE8B phosphodiesterase 8B
PDZK1 PDZ domain containing 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PWAR5 Prader Willi/Angelman region RNA 5
RAB25 RAB25, member RAS oncogene family
RNF25 ring finger protein 25
RSL24D1 ribosomal L24 domain containing 1
S100A3 S100 calcium binding protein A3
SCAMP5 secretory carrier membrane protein 5
SELT selenoprotein T
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SESN1 sestrin 1
SH2D4A SH2 domain containing 4A
SH3TC2 SH3 domain and tetratricopeptide repeats 2
STAC SH3 and cysteine rich domain
STK16 serine/threonine kinase 16
STRN striatin, calmodulin binding protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THRAP3 thyroid hormone receptor associated protein 3
TPCN1 two pore segment channel 1
TRIM25 tripartite motif containing 25
TSPAN1 tetraspanin 1
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
WDR18 WD repeat domain 18
WDR62 WD repeat domain 62
ZNF16 zinc finger protein 16
ZNF711 zinc finger protein 711