| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the hesperidin-6714 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACO2 | aconitase 2, mitochondrial |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACTN2 | actinin, alpha 2 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ANGPTL2 | angiopoietin-like 2 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CACNG5 | calcium channel, voltage-dependent, gamma subunit 5 |
| CARTPT | CART prepropeptide |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD6 | CD6 molecule |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLEC7A | C-type lectin domain family 7, member A |
| CLIC5 | chloride intracellular channel 5 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRTAC1 | cartilage acidic protein 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CST1 | cystatin SN |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DCLK2 | doublecortin-like kinase 2 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DLC1 | DLC1 Rho GTPase activating protein |
| DRD2 | dopamine receptor D2 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| FGF18 | fibroblast growth factor 18 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FOXF1 | forkhead box F1 |
| GALR2 | galanin receptor 2 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HRG | histidine-rich glycoprotein |
| IFNA6 | interferon, alpha 6 |
| ITGA7 | integrin, alpha 7 |
| ITGB6 | integrin, beta 6 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KERA | keratocan |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLHDC8A | kelch domain containing 8A |
| KRT19P2 | keratin 19 pseudogene 2 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LRMP | lymphoid-restricted membrane protein |
| MED25 | mediator complex subunit 25 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MMP10 | matrix metallopeptidase 10 |
| MMP3 | matrix metallopeptidase 3 |
| MPO | myeloperoxidase |
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAX2 | paired box 2 |
| PAX8 | paired box 8 |
| PCDHB3 | protocadherin beta 3 |
| PHF7 | PHD finger protein 7 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRAMEF11 | PRAME family member 11 |
| PRM2 | protamine 2 |
| RASAL2 | RAS protein activator like 2 |
| RBBP9 | retinoblastoma binding protein 9 |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| REEP1 | receptor accessory protein 1 |
| RPS3A | ribosomal protein S3A |
| RUNX1 | runt-related transcription factor 1 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SMAD1 | SMAD family member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SPRR2B | small proline-rich protein 2B |
| SRRT | serrate, RNA effector molecule |
| SYT12 | synaptotagmin XII |
| TAAR5 | trace amine associated receptor 5 |
| TACR1 | tachykinin receptor 1 |
| TAS2R13 | taste receptor, type 2, member 13 |
| TLR4 | toll-like receptor 4 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TOX | thymocyte selection-associated high mobility group box |
| TRIM3 | tripartite motif containing 3 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WISP2 | WNT1 inducible signaling pathway protein 2 |
| ZNF117 | zinc finger protein 117 |
| ZNF268 | zinc finger protein 268 |
| ZNF556 | zinc finger protein 556 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BEX4 | brain expressed, X-linked 4 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBX8 | chromobox homolog 8 |
| CCNJ | cyclin J |
| CD9 | CD9 molecule |
| CDC37L1 | cell division cycle 37-like 1 |
| CDH7 | cadherin 7, type 2 |
| CEP85 | centrosomal protein 85kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CHMP1B | charged multivesicular body protein 1B |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN4 | claudin 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DCP1A | decapping mRNA 1A |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DUSP8 | dual specificity phosphatase 8 |
| EAF2 | ELL associated factor 2 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EXOC5 | exocyst complex component 5 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FKBP5 | FK506 binding protein 5 |
| FNTB | farnesyltransferase, CAAX box, beta |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GTF2I | general transcription factor IIi |
| H2BFS | H2B histone family, member S (pseudogene) |
| HDAC5 | histone deacetylase 5 |
| HELZ | helicase with zinc finger |
| HIST1H2AM | histone cluster 1, H2am |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| KRT4 | keratin 4, type II |
| KRT75 | keratin 75, type II |
| KRT8P12 | keratin 8 pseudogene 12 |
| LOC100127972 | uncharacterized LOC100127972 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAGEH1 | melanoma antigen family H1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCOLN1 | mucolipin 1 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MITF | microphthalmia-associated transcription factor |
| MOSPD3 | motile sperm domain containing 3 |
| NDRG4 | NDRG family member 4 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OLFML3 | olfactomedin-like 3 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE8B | phosphodiesterase 8B |
| PDZK1 | PDZ domain containing 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB25 | RAB25, member RAS oncogene family |
| RNF25 | ring finger protein 25 |
| RSL24D1 | ribosomal L24 domain containing 1 |
| S100A3 | S100 calcium binding protein A3 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SELT | selenoprotein T |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SESN1 | sestrin 1 |
| SH2D4A | SH2 domain containing 4A |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| STAC | SH3 and cysteine rich domain |
| STK16 | serine/threonine kinase 16 |
| STRN | striatin, calmodulin binding protein |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TPCN1 | two pore segment channel 1 |
| TRIM25 | tripartite motif containing 25 |
| TSPAN1 | tetraspanin 1 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
| WDR18 | WD repeat domain 18 |
| WDR62 | WD repeat domain 62 |
| ZNF16 | zinc finger protein 16 |
| ZNF711 | zinc finger protein 711 |