| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the hexestrol-5776 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOXL | acyl-CoA oxidase-like |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATXN7L1 | ataxin 7-like 1 |
| AURKC | aurora kinase C |
| BAIAP3 | BAI1-associated protein 3 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C3 | complement component 3 |
| CA14 | carbonic anhydrase XIV |
| CADM3 | cell adhesion molecule 3 |
| CASC1 | cancer susceptibility candidate 1 |
| CCDC28B | coiled-coil domain containing 28B |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHAT | choline O-acetyltransferase |
| CIC | capicua transcriptional repressor |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CTSZ | cathepsin Z |
| DCHS1 | dachsous cadherin-related 1 |
| DKFZP434L187 | uncharacterized LOC26082 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPO | erythropoietin |
| ESR1 | estrogen receptor 1 |
| ESRRG | estrogen-related receptor gamma |
| FAM65B | family with sequence similarity 65, member B |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPR182 | G protein-coupled receptor 182 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HIST1H3E | histone cluster 1, H3e |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGHM | immunoglobulin heavy constant mu |
| IL1R2 | interleukin 1 receptor, type II |
| IL24 | interleukin 24 |
| INO80B | INO80 complex subunit B |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNB1 | potassium channel, voltage gated Shab related subfamily B, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIF1A | kinesin family member 1A |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KRT2 | keratin 2, type II |
| KRT38 | keratin 38, type I |
| LIMD2 | LIM domain containing 2 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LOX | lysyl oxidase |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MED25 | mediator complex subunit 25 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| NCR1 | natural cytotoxicity triggering receptor 1 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NOX1 | NADPH oxidase 1 |
| OGFR | opioid growth factor receptor |
| PADI2 | peptidyl arginine deiminase, type II |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PLIN2 | perilipin 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU6F1 | POU class 6 homeobox 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RGS11 | regulator of G-protein signaling 11 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC6A16 | solute carrier family 6, member 16 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TRIM10 | tripartite motif containing 10 |
| TRIM29 | tripartite motif containing 29 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TYMS | thymidylate synthetase |
| VRTN | vertebrae development associated |
| ZNF224 | zinc finger protein 224 |
| ZNF749 | zinc finger protein 749 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADCY6 | adenylate cyclase 6 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AKTIP | AKT interacting protein |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| AXIN1 | axin 1 |
| AZI2 | 5-azacytidine induced 2 |
| BAX | BCL2-associated X protein |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNJL | cyclin J-like |
| CLDN11 | claudin 11 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DBF4B | DBF4 zinc finger B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF13 | fibroblast growth factor 13 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIRA | histone cell cycle regulator |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3B | histone cluster 1, H3b |
| HOXC8 | homeobox C8 |
| IPO8 | importin 8 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0754 | KIAA0754 |
| KIAA0895 | KIAA0895 |
| KRT15 | keratin 15, type I |
| KRT86 | keratin 86, type II |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBTD1 | mbt domain containing 1 |
| MYL9 | myosin, light chain 9, regulatory |
| MYO1D | myosin ID |
| NDRG4 | NDRG family member 4 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| ODF2 | outer dense fiber of sperm tails 2 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE8B | phosphodiesterase 8B |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRSS8 | protease, serine, 8 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF2 | ring finger protein 2 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMAD7 | SMAD family member 7 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPIDR | scaffolding protein involved in DNA repair |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBX19 | T-box 19 |
| TCTN2 | tectonic family member 2 |
| TEX40 | testis expressed 40 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMC7 | transmembrane channel-like 7 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM159 | transmembrane protein 159 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM45 | tripartite motif containing 45 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| UGT8 | UDP glycosyltransferase 8 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF671 | zinc finger protein 671 |
| ZNF76 | zinc finger protein 76 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
