| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hexestrol-6077 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADM | adrenomedullin |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ATF3 | activating transcription factor 3 |
| AVPR1B | arginine vasopressin receptor 1B |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL6 | B-cell CLL/lymphoma 6 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CALCR | calcitonin receptor |
| CAMKV | CaM kinase-like vesicle-associated |
| CCNK | cyclin K |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL10A1 | collagen, type X, alpha 1 |
| CPN1 | carboxypeptidase N, polypeptide 1 |
| CRH | corticotropin releasing hormone |
| CRISP2 | cysteine-rich secretory protein 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DRD2 | dopamine receptor D2 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| FAM182B | family with sequence similarity 182, member B |
| FAM46C | family with sequence similarity 46, member C |
| FCGBP | Fc fragment of IgG binding protein |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRMD1 | FERM domain containing 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLB1L | galactosidase, beta 1-like |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HPX | hemopexin |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INE1 | inactivation escape 1 (non-protein coding) |
| INHBE | inhibin, beta E |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JUN | jun proto-oncogene |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIFC3 | kinesin family member C3 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT75 | keratin 75, type II |
| LIF | leukemia inhibitory factor |
| LUZP4 | leucine zipper protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPK11 | mitogen-activated protein kinase 11 |
| MUC3B | mucin 3B, cell surface associated |
| MXD1 | MAX dimerization protein 1 |
| NOV | nephroblastoma overexpressed |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUP214 | nucleoporin 214kDa |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| OTOR | otoraplin |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PARVA | parvin, alpha |
| PDLIM5 | PDZ and LIM domain 5 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| POU3F4 | POU class 3 homeobox 4 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PROX1 | prospero homeobox 1 |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAI2 | retinoic acid induced 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RUNX1 | runt-related transcription factor 1 |
| S100A9 | S100 calcium binding protein A9 |
| SAFB | scaffold attachment factor B |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SIRT4 | sirtuin 4 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNTA1 | syntrophin, alpha 1 |
| STAC | SH3 and cysteine rich domain |
| TBXA2R | thromboxane A2 receptor |
| TEX40 | testis expressed 40 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMEM204 | transmembrane protein 204 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNIK | TRAF2 and NCK interacting kinase |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| TTC38 | tetratricopeptide repeat domain 38 |
| ULBP1 | UL16 binding protein 1 |
| VIL1 | villin 1 |
| Symbol | Name |
|---|---|
| ALS2CL | ALS2 C-terminal like |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BEX4 | brain expressed, X-linked 4 |
| BMP4 | bone morphogenetic protein 4 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAPN5 | calpain 5 |
| CASD1 | CAS1 domain containing 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CD82 | CD82 molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHKB | choline kinase beta |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO7 | coronin 7 |
| CRY2 | cryptochrome circadian clock 2 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP9 | dual specificity phosphatase 9 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| FAM198B | family with sequence similarity 198, member B |
| FOXJ2 | forkhead box J2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GHR | growth hormone receptor |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR27 | G protein-coupled receptor 27 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HAMP | hepcidin antimicrobial peptide |
| HOXA4 | homeobox A4 |
| IFI35 | interferon-induced protein 35 |
| INO80D | INO80 complex subunit D |
| IRF2 | interferon regulatory factor 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0125 | KIAA0125 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MDM4 | MDM4, p53 regulator |
| MSI1 | musashi RNA-binding protein 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| MXRA7 | matrix-remodelling associated 7 |
| NABP2 | nucleic acid binding protein 2 |
| NOL10 | nucleolar protein 10 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POLL | polymerase (DNA directed), lambda |
| PP14571 | uncharacterized LOC100130449 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTK6 | protein tyrosine kinase 6 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB23 | RAB23, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| SETD1A | SET domain containing 1A |
| SETD6 | SET domain containing 6 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SIX1 | SIX homeobox 1 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNX16 | sorting nexin 16 |
| SP1 | Sp1 transcription factor |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D17 | TBC1 domain family, member 17 |
| TCHH | trichohyalin |
| TDRD1 | tudor domain containing 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMC7 | transmembrane channel-like 7 |
| TMEM165 | transmembrane protein 165 |
| TMEM180 | transmembrane protein 180 |
| TMEM53 | transmembrane protein 53 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRIM21 | tripartite motif containing 21 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| VAX2 | ventral anterior homeobox 2 |
| WBP2 | WW domain binding protein 2 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WLS | wntless Wnt ligand secretion mediator |
| XK | X-linked Kx blood group |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF134 | zinc finger protein 134 |
| ZNF219 | zinc finger protein 219 |
