| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hexestrol-6252 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ADCK2 | aarF domain containing kinase 2 |
| ALPK1 | alpha-kinase 1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AREG | amphiregulin |
| ATF3 | activating transcription factor 3 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| CDH8 | cadherin 8, type 2 |
| CRYGC | crystallin, gamma C |
| CSF1R | colony stimulating factor 1 receptor |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNPEP | aspartyl aminopeptidase |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EML3 | echinoderm microtubule associated protein like 3 |
| FAM46C | family with sequence similarity 46, member C |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FRMD4B | FERM domain containing 4B |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPR27 | G protein-coupled receptor 27 |
| GRB10 | growth factor receptor-bound protein 10 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H2BN | histone cluster 1, H2bn |
| HOXC8 | homeobox C8 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| ICOS | inducible T-cell co-stimulator |
| IFT54 | intraflagellar transport 54 |
| IL27RA | interleukin 27 receptor, alpha |
| IL4R | interleukin 4 receptor |
| IL6ST | interleukin 6 signal transducer |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITGA10 | integrin, alpha 10 |
| JUN | jun proto-oncogene |
| KHK | ketohexokinase (fructokinase) |
| KLF6 | Kruppel-like factor 6 |
| KLHL25 | kelch-like family member 25 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MC5R | melanocortin 5 receptor |
| MEP1B | meprin A, beta |
| MVD | mevalonate (diphospho) decarboxylase |
| MYOF | myoferlin |
| NUP188 | nucleoporin 188kDa |
| PDCD2 | programmed cell death 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PITX1 | paired-like homeodomain 1 |
| PLD3 | phospholipase D family, member 3 |
| PLK4 | polo-like kinase 4 |
| PLSCR3 | phospholipid scramblase 3 |
| PLXNA1 | plexin A1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRF1 | perforin 1 (pore forming protein) |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTX3 | pentraxin 3, long |
| RBM19 | RNA binding motif protein 19 |
| RGS2 | regulator of G-protein signaling 2 |
| RORC | RAR-related orphan receptor C |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SETD1A | SET domain containing 1A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TLR2 | toll-like receptor 2 |
| TRD | T cell receptor delta locus |
| TSPYL2 | TSPY-like 2 |
| TYMS | thymidylate synthetase |
| USB1 | U6 snRNA biogenesis 1 |
| USP34 | ubiquitin specific peptidase 34 |
| VAX2 | ventral anterior homeobox 2 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF428 | zinc finger protein 428 |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AHR | aryl hydrocarbon receptor |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANKRD28 | ankyrin repeat domain 28 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BAX | BCL2-associated X protein |
| BCORL1 | BCL6 corepressor-like 1 |
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C5 | complement component 5 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC85C | coiled-coil domain containing 85C |
| CDKL3 | cyclin-dependent kinase-like 3 |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DCP1A | decapping mRNA 1A |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EVPL | envoplakin |
| F8 | coagulation factor VIII, procoagulant component |
| FAM193B | family with sequence similarity 193, member B |
| FANCC | Fanconi anemia, complementation group C |
| GAS8 | growth arrest-specific 8 |
| GHR | growth hormone receptor |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GOLGA8B | golgin A8 family, member B |
| GPALPP1 | GPALPP motifs containing 1 |
| GPR137B | G protein-coupled receptor 137B |
| GSTT1 | glutathione S-transferase theta 1 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIRA | histone cell cycle regulator |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT81 | intraflagellar transport 81 |
| IL15RA | interleukin 15 receptor, alpha |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRF6 | interferon regulatory factor 6 |
| IRX4 | iroquois homeobox 4 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF1B | kinesin family member 1B |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMNB1 | lamin B1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYRM9 | LYR motif containing 9 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MICALL2 | MICAL-like 2 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| NECAP1 | NECAP endocytosis associated 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SETMAR | SET domain and mariner transposase fusion gene |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SOAT1 | sterol O-acyltransferase 1 |
| STBD1 | starch binding domain 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STXBP2 | syntaxin binding protein 2 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TDRD1 | tudor domain containing 1 |
| TESK1 | testis-specific kinase 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF5 | TNF receptor-associated factor 5 |
| VASP | vasodilator-stimulated phosphoprotein |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF248 | zinc finger protein 248 |
| ZNF273 | zinc finger protein 273 |
| ZNF276 | zinc finger protein 276 |
| ZNF552 | zinc finger protein 552 |
| ZNF668 | zinc finger protein 668 |
| ZNF816 | zinc finger protein 816 |
