| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hexetidine-2457 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AREG | amphiregulin |
| AURKA | aurora kinase A |
| AXL | AXL receptor tyrosine kinase |
| BAIAP2 | BAI1-associated protein 2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| C1ORF68 | chromosome 1 open reading frame 68 |
| CD38 | CD38 molecule |
| CREM | cAMP responsive element modulator |
| CSF1 | colony stimulating factor 1 (macrophage) |
| DCT | dopachrome tautomerase |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK4 | dedicator of cytokinesis 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EML2 | echinoderm microtubule associated protein like 2 |
| FADS3 | fatty acid desaturase 3 |
| FCAR | Fc fragment of IgA receptor |
| FGF20 | fibroblast growth factor 20 |
| FOXO4 | forkhead box O4 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR183 | G protein-coupled receptor 183 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| INE1 | inactivation escape 1 (non-protein coding) |
| ING2 | inhibitor of growth family, member 2 |
| IRF4 | interferon regulatory factor 4 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIF1C | kinesin family member 1C |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KYNU | kynureninase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCAM | melanoma cell adhesion molecule |
| MRC2 | mannose receptor, C type 2 |
| MX1 | MX dynamin-like GTPase 1 |
| MX2 | MX dynamin-like GTPase 2 |
| NAG18 | NAG18 mRNA |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NOX1 | NADPH oxidase 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PARVB | parvin, beta |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PICK1 | protein interacting with PRKCA 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLCH1 | phospholipase C, eta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLSCR1 | phospholipid scramblase 1 |
| POLL | polymerase (DNA directed), lambda |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PYGB | phosphorylase, glycogen; brain |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASAL2 | RAS protein activator like 2 |
| RB1 | retinoblastoma 1 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RIN2 | Ras and Rab interactor 2 |
| RUNX1 | runt-related transcription factor 1 |
| SDC2 | syndecan 2 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SFRP5 | secreted frizzled-related protein 5 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SKIL | SKI-like proto-oncogene |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMAD6 | SMAD family member 6 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| THBS1 | thrombospondin 1 |
| TYMP | thymidine phosphorylase |
| USP2 | ubiquitin specific peptidase 2 |
| VGF | VGF nerve growth factor inducible |
| WDR25 | WD repeat domain 25 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AMPH | amphiphysin |
| ANKRD40 | ankyrin repeat domain 40 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CEP295 | centrosomal protein 295kDa |
| CES3 | carboxylesterase 3 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CTC1 | CTS telomere maintenance complex component 1 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| EFNA3 | ephrin-A3 |
| EGR2 | early growth response 2 |
| EMID1 | EMI domain containing 1 |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR63 | G protein-coupled receptor 63 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC7 | histone deacetylase 7 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BN | histone cluster 1, H2bn |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC8 | homeobox C8 |
| HSPA2 | heat shock 70kDa protein 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KLHL28 | kelch-like family member 28 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LIMD2 | LIM domain containing 2 |
| LOC257152 | uncharacterized LOC257152 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MDM4 | MDM4, p53 regulator |
| MEFV | Mediterranean fever |
| MMP3 | matrix metallopeptidase 3 |
| MMP9 | matrix metallopeptidase 9 |
| NCALD | neurocalcin delta |
| NEUROD4 | neuronal differentiation 4 |
| NKX3-2 | NK3 homeobox 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NSUN3 | NOP2/Sun domain family, member 3 |
| OCEL1 | occludin/ELL domain containing 1 |
| OLFML2A | olfactomedin-like 2A |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDGFD | platelet derived growth factor D |
| PER3 | period circadian clock 3 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHACTR1 | phosphatase and actin regulator 1 |
| PIP | prolactin-induced protein |
| PMP22 | peripheral myelin protein 22 |
| PODXL2 | podocalyxin-like 2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| QSER1 | glutamine and serine rich 1 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RNF25 | ring finger protein 25 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SH2D4A | SH2 domain containing 4A |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SRPX | sushi-repeat containing protein, X-linked |
| STX11 | syntaxin 11 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBC1D19 | TBC1 domain family, member 19 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM242 | transmembrane protein 242 |
| TNS2 | tensin 2 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBTD1 | ubiquitin domain containing 1 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR62 | WD repeat domain 62 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF225 | zinc finger protein 225 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF480 | zinc finger protein 480 |
| ZNF493 | zinc finger protein 493 |
| ZNF552 | zinc finger protein 552 |
| ZNF816 | zinc finger protein 816 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
