hexetidine-3318 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the hexetidine-3318 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN1 actinin, alpha 1
ADAP1 ArfGAP with dual PH domains 1
AKAP7 A kinase (PRKA) anchor protein 7
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ARHGAP44 Rho GTPase activating protein 44
ARTN artemin
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BIN1 bridging integrator 1
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
CADM3 cell adhesion molecule 3
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
EFNA1 ephrin-A1
EGFL7 EGF-like-domain, multiple 7
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR2 early growth response 2
EGR4 early growth response 4
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GPR137 G protein-coupled receptor 137
GPR87 G protein-coupled receptor 87
HBEGF heparin-binding EGF-like growth factor
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
HPX hemopexin
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1B interleukin 1, beta
INHBE inhibin, beta E
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JUN jun proto-oncogene
JUND jun D proto-oncogene
KIAA0319L KIAA0319-like
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LYPD1 LY6/PLAUR domain containing 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MKL1 megakaryoblastic leukemia (translocation) 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP2L2 NEDD4 binding protein 2-like 2
N4BP3 NEDD4 binding protein 3
NBL1 neuroblastoma 1, DAN family BMP antagonist
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OBSL1 obscurin-like 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
SRCAP Snf2-related CREBBP activator protein
SRSF7 serine/arginine-rich splicing factor 7
TBXA2R thromboxane A2 receptor
TMLHE trimethyllysine hydroxylase, epsilon
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOR4A torsin family 4, member A
VEGFA vascular endothelial growth factor A
WDTC1 WD and tetratricopeptide repeats 1
ZER1 zyg-11 related, cell cycle regulator
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACTL8 actin-like 8
AGMAT agmatine ureohydrolase (agmatinase)
AHNAK2 AHNAK nucleoprotein 2
ALPK1 alpha-kinase 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C11ORF21 chromosome 11 open reading frame 21
C16ORF62 chromosome 16 open reading frame 62
C2ORF54 chromosome 2 open reading frame 54
C3 complement component 3
C8ORF44 chromosome 8 open reading frame 44
C9ORF9 chromosome 9 open reading frame 9
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CTSF cathepsin F
DMTN dematin actin binding protein
DTX2 deltex 2, E3 ubiquitin ligase
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
ERCC4 excision repair cross-complementation group 4
FAM86C1 family with sequence similarity 86, member C1
FBXL7 F-box and leucine-rich repeat protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GEMIN8 gem (nuclear organelle) associated protein 8
GIF gastric intrinsic factor (vitamin B synthesis)
HAUS2 HAUS augmin-like complex, subunit 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXC5 homeobox C5
IFI6 interferon, alpha-inducible protein 6
IFT140 intraflagellar transport 140
IPP intracisternal A particle-promoted polypeptide
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM5C lysine (K)-specific demethylase 5C
LIME1 Lck interacting transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LOC390998 ribosomal protein L10 pseudogene
LRRC6 leucine rich repeat containing 6
LTC4S leukotriene C4 synthase
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MBNL3 muscleblind-like splicing regulator 3
MED18 mediator complex subunit 18
MGC12488
MRPL44 mitochondrial ribosomal protein L44
NPIPB15 nuclear pore complex interacting protein family, member B15
NRSN2 neurensin 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHA6 protocadherin alpha 6
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDIA3 protein disulfide isomerase family A, member 3
PHACTR4 phosphatase and actin regulator 4
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMEL premelanosome protein
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTCD2 pentatricopeptide repeat domain 2
RAB3A RAB3A, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RLN1 relaxin 1
RNF122 ring finger protein 122
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SDC3 syndecan 3
SH2D4A SH2 domain containing 4A
SIX1 SIX homeobox 1
SLC16A6 solute carrier family 16, member 6
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLN sarcolipin
SND1-IT1 SND1 intronic transcript 1
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TSPAN14 tetraspanin 14
TTLL1 tubulin tyrosine ligase-like family member 1
UBQLN4 ubiquilin 4
USP18 ubiquitin specific peptidase 18
USP27X ubiquitin specific peptidase 27, X-linked
VGF VGF nerve growth factor inducible
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFP37 ZFP37 zinc finger protein
ZNF219 zinc finger protein 219
ZNF350 zinc finger protein 350
ZNF532 zinc finger protein 532
ZNF652 zinc finger protein 652
ZNRD1-AS1 ZNRD1 antisense RNA 1