| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the hexetidine-5420 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| AFAP1 | actin filament associated protein 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALS2CL | ALS2 C-terminal like |
| AMPD3 | adenosine monophosphate deaminase 3 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ART1 | ADP-ribosyltransferase 1 |
| ATF3 | activating transcription factor 3 |
| BAIAP3 | BAI1-associated protein 3 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BMP15 | bone morphogenetic protein 15 |
| BMP5 | bone morphogenetic protein 5 |
| CCNG2 | cyclin G2 |
| CD47 | CD47 molecule |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CGA | glycoprotein hormones, alpha polypeptide |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| DAPK2 | death-associated protein kinase 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EGR4 | early growth response 4 |
| ETV5 | ets variant 5 |
| FAM186A | family with sequence similarity 186, member A |
| FAM65B | family with sequence similarity 65, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO2 | F-box protein 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3I | histone cluster 1, H3i |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMOX1 | heme oxygenase 1 |
| HOXA10 | homeobox A10 |
| HOXB2 | homeobox B2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| INHBE | inhibin, beta E |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JUN | jun proto-oncogene |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KLF13 | Kruppel-like factor 13 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLF9 | Kruppel-like factor 9 |
| LDHB | lactate dehydrogenase B |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MBD3 | methyl-CpG binding domain protein 3 |
| MCAM | melanoma cell adhesion molecule |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MORC1 | MORC family CW-type zinc finger 1 |
| MST1 | macrophage stimulating 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MTSS1L | metastasis suppressor 1-like |
| MYEF2 | myelin expression factor 2 |
| MYO9B | myosin IXB |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NF1 | neurofibromin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PARVB | parvin, beta |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRSS53 | protease, serine, 53 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RND1 | Rho family GTPase 1 |
| RPL10 | ribosomal protein L10 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SRCAP | Snf2-related CREBBP activator protein |
| TBC1D2B | TBC1 domain family, member 2B |
| TBX6 | T-box 6 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| UNC93A | unc-93 homolog A (C. elegans) |
| VIM | vimentin |
| YY2 | YY2 transcription factor |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF236 | zinc finger protein 236 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| B9D2 | B9 protein domain 2 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BST2 | bone marrow stromal cell antigen 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CA11 | carbonic anhydrase XI |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEP170B | centrosomal protein 170B |
| CES3 | carboxylesterase 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTSF | cathepsin F |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK1 | dedicator of cytokinesis 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GPR19 | G protein-coupled receptor 19 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXC5 | homeobox C5 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGFLR1 | IGF-like family receptor 1 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF6 | interferon regulatory factor 6 |
| KIF13A | kinesin family member 13A |
| KRT15 | keratin 15, type I |
| LHX6 | LIM homeobox 6 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMNB1 | lamin B1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MDM4 | MDM4, p53 regulator |
| MGC12488 | |
| MNS1 | meiosis-specific nuclear structural 1 |
| MSMB | microseminoprotein, beta- |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NME5 | NME/NM23 family member 5 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPFFR1 | neuropeptide FF receptor 1 |
| OLFML2A | olfactomedin-like 2A |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| QSER1 | glutamine and serine rich 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RANGRF | RAN guanine nucleotide release factor |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPAP1 | RNA polymerase II associated protein 1 |
| S100A9 | S100 calcium binding protein A9 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUOX | sulfite oxidase |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBX19 | T-box 19 |
| TCHH | trichohyalin |
| TMEM180 | transmembrane protein 180 |
| TMEM242 | transmembrane protein 242 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VGF | VGF nerve growth factor inducible |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF276 | zinc finger protein 276 |
| ZNF74 | zinc finger protein 74 |
