| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the hexetidine-6319 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ALB | albumin |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| ATF3 | activating transcription factor 3 |
| ATXN1 | ataxin 1 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CALD1 | caldesmon 1 |
| CDHR2 | cadherin-related family member 2 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COL7A1 | collagen, type VII, alpha 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CTTN | cortactin |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EHF | ets homologous factor |
| EPAS1 | endothelial PAS domain protein 1 |
| FAM110B | family with sequence similarity 110, member B |
| FAM134B | family with sequence similarity 134, member B |
| FGF23 | fibroblast growth factor 23 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GPC3 | glypican 3 |
| GPR161 | G protein-coupled receptor 161 |
| HDAC9 | histone deacetylase 9 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXB5 | homeobox B5 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IDS | iduronate 2-sulfatase |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGL | immunoglobulin lambda locus |
| IL5RA | interleukin 5 receptor, alpha |
| IL6 | interleukin 6 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LHX2 | LIM homeobox 2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| MVK | mevalonate kinase |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NRXN3 | neurexin 3 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| ODF2 | outer dense fiber of sperm tails 2 |
| PLCG1 | phospholipase C, gamma 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTEN | phosphatase and tensin homolog |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RARG | retinoic acid receptor, gamma |
| REEP1 | receptor accessory protein 1 |
| RFPL1 | ret finger protein-like 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STAT5B | signal transducer and activator of transcription 5B |
| STC1 | stanniocalcin 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUGP1 | SURP and G patch domain containing 1 |
| TMEM259 | transmembrane protein 259 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WDR1 | WD repeat domain 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| AFAP1 | actin filament associated protein 1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARMC4 | armadillo repeat containing 4 |
| ARRB2 | arrestin, beta 2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BAK1 | BCL2-antagonist/killer 1 |
| BEND5 | BEN domain containing 5 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CHKB | choline kinase beta |
| CISH | cytokine inducible SH2-containing protein |
| CLSPN | claspin |
| CNN2 | calponin 2 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DOLK | dolichol kinase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ETV4 | ets variant 4 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH2L | G patch domain containing 2-like |
| GPX2 | glutathione peroxidase 2 |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC5 | histone deacetylase 5 |
| HIST1H2BM | histone cluster 1, H2bm |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA4 | homeobox A4 |
| HOXC4 | homeobox C4 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI35 | interferon-induced protein 35 |
| IL15RA | interleukin 15 receptor, alpha |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0753 | KIAA0753 |
| LIFR | leukemia inhibitory factor receptor alpha |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MANBA | mannosidase, beta A, lysosomal |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MYL5 | myosin, light chain 5, regulatory |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NOP2 | NOP2 nucleolar protein |
| NXPH4 | neurexophilin 4 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PALMD | palmdelphin |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PKN1 | protein kinase N1 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAME | preferentially expressed antigen in melanoma |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR7 | proline rich 7 (synaptic) |
| PSKH1 | protein serine kinase H1 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTGES2 | prostaglandin E synthase 2 |
| RAB5B | RAB5B, member RAS oncogene family |
| RBM42 | RNA binding motif protein 42 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN1 | Ras and Rab interactor 1 |
| SAA4 | serum amyloid A4, constitutive |
| SCAI | suppressor of cancer cell invasion |
| SIRT6 | sirtuin 6 |
| SIX1 | SIX homeobox 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SYTL2 | synaptotagmin-like 2 |
| TEX40 | testis expressed 40 |
| THAP7 | THAP domain containing 7 |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM121 | transmembrane protein 121 |
| TUBG2 | tubulin, gamma 2 |
| UBQLN4 | ubiquilin 4 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZNF141 | zinc finger protein 141 |
| ZNF215 | zinc finger protein 215 |
| ZNF268 | zinc finger protein 268 |
| ZNF34 | zinc finger protein 34 |
| ZNF574 | zinc finger protein 574 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |