| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hexylcaine-2708 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADRA1A | adrenoceptor alpha 1A |
| AGFG2 | ArfGAP with FG repeats 2 |
| APOB | apolipoprotein B |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| APP | amyloid beta (A4) precursor protein |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDHR2 | cadherin-related family member 2 |
| CFHR5 | complement factor H-related 5 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLDN3 | claudin 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL11A1 | collagen, type XI, alpha 1 |
| CRAT | carnitine O-acetyltransferase |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DCN | decorin |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DEPDC5 | DEP domain containing 5 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DSCR4 | Down syndrome critical region 4 |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EML2 | echinoderm microtubule associated protein like 2 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GATA2 | GATA binding protein 2 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR3 | G protein-coupled receptor 3 |
| GRK4 | G protein-coupled receptor kinase 4 |
| HAMP | hepcidin antimicrobial peptide |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HOXA6 | homeobox A6 |
| HSPA2 | heat shock 70kDa protein 2 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| INSR | insulin receptor |
| ITGA9 | integrin, alpha 9 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0040 | KIAA0040 |
| KIAA0125 | KIAA0125 |
| KIF1C | kinesin family member 1C |
| LMTK1 | lemur tail kinase 1 |
| LRRC48 | leucine rich repeat containing 48 |
| LRRN3 | leucine rich repeat neuronal 3 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MARC2 | mitochondrial amidoxime reducing component 2 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| MTSS1 | metastasis suppressor 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PICK1 | protein interacting with PRKCA 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCE1 | phospholipase C, epsilon 1 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POLL | polymerase (DNA directed), lambda |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RGS4 | regulator of G-protein signaling 4 |
| RNASE3 | ribonuclease, RNase A family, 3 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SETBP1 | SET binding protein 1 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TBCD | tubulin folding cofactor D |
| TBKBP1 | TBK1 binding protein 1 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TEX15 | testis expressed 15 |
| TRIM3 | tripartite motif containing 3 |
| TRIM31 | tripartite motif containing 31 |
| TRPM1 | transient receptor potential cation channel, subfamily M, member 1 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF155 | zinc finger protein 155 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACP2 | acid phosphatase 2, lysosomal |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC71 | coiled-coil domain containing 71 |
| CD9 | CD9 molecule |
| CEP97 | centrosomal protein 97kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CROT | carnitine O-octanoyltransferase |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| EFNA3 | ephrin-A3 |
| EGR2 | early growth response 2 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM163A | family with sequence similarity 163, member A |
| FAM204A | family with sequence similarity 204, member A |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOXD2 | forkhead box D2 |
| GAS2 | growth arrest-specific 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GMPR | guanosine monophosphate reductase |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HOXC8 | homeobox C8 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IRS1 | insulin receptor substrate 1 |
| IRS4 | insulin receptor substrate 4 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KLF13 | Kruppel-like factor 13 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MEP1B | meprin A, beta |
| METRN | meteorin, glial cell differentiation regulator |
| MTA2 | metastasis associated 1 family, member 2 |
| MVP | major vault protein |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NBEA | neurobeachin |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NEUROD4 | neuronal differentiation 4 |
| NNAT | neuronatin |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PCDH12 | protocadherin 12 |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLTP | phospholipid transfer protein |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKCZ | protein kinase C, zeta |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RFPL3S | RFPL3 antisense |
| RFXAP | regulatory factor X-associated protein |
| RGS13 | regulator of G-protein signaling 13 |
| RHOH | ras homolog family member H |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPL10L | ribosomal protein L10-like |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRAGB | Ras-related GTP binding B |
| SCRN3 | secernin 3 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUSD5 | sushi domain containing 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM212 | transmembrane protein 212 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TPM3 | tropomyosin 3 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR76 | WD repeat domain 76 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF428 | zinc finger protein 428 |
| ZNF669 | zinc finger protein 669 |
| ZNF778 | zinc finger protein 778 |
