| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hexylcaine-3447 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ATP10B | ATPase, class V, type 10B |
| BMP2K | BMP2 inducible kinase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC68 | coiled-coil domain containing 68 |
| CDC25C | cell division cycle 25C |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CLCA2 | chloride channel accessory 2 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| COL6A1 | collagen, type VI, alpha 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DIO2 | deiodinase, iodothyronine, type II |
| DOPEY2 | dopey family member 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPN2 | epsin 2 |
| EPX | eosinophil peroxidase |
| FAM186A | family with sequence similarity 186, member A |
| FAM212B | family with sequence similarity 212, member B |
| FAM214B | family with sequence similarity 214, member B |
| FOXN3 | forkhead box N3 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GK2 | glycerol kinase 2 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HFE | hemochromatosis |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HMOX1 | heme oxygenase 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IGHD | immunoglobulin heavy constant delta |
| IL15RA | interleukin 15 receptor, alpha |
| IL1B | interleukin 1, beta |
| ITGB5 | integrin, beta 5 |
| KIAA0930 | KIAA0930 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT17 | keratin 17, type I |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LHX6 | LIM homeobox 6 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LIMK2 | LIM domain kinase 2 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MAP4 | microtubule-associated protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MED15 | mediator complex subunit 15 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCALD | neurocalcin delta |
| NGLY1 | N-glycanase 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDLIM3 | PDZ and LIM domain 3 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PROL1 | proline rich, lacrimal 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| PTHLH | parathyroid hormone-like hormone |
| RARA | retinoic acid receptor, alpha |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RETN | resistin |
| RNF2 | ring finger protein 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SIX2 | SIX homeobox 2 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPRR1B | small proline-rich protein 1B |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| TCHH | trichohyalin |
| TH | tyrosine hydroxylase |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOR4A | torsin family 4, member A |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM36 | tripartite motif containing 36 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WNK1 | WNK lysine deficient protein kinase 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF304 | zinc finger protein 304 |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ANXA1 | annexin A1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNL2 | cyclin L2 |
| CDK3 | cyclin-dependent kinase 3 |
| CLDND1 | claudin domain containing 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CORO2A | coronin, actin binding protein, 2A |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CTAGE9 | CTAGE family, member 9 |
| CTBS | chitobiase, di-N-acetyl- |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC3 | excision repair cross-complementation group 3 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FCHO1 | FCH domain only 1 |
| FKBP5 | FK506 binding protein 5 |
| FOCAD | focadhesin |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLCE | glucuronic acid epimerase |
| GPKOW | G patch domain and KOW motifs |
| GPR143 | G protein-coupled receptor 143 |
| GPR87 | G protein-coupled receptor 87 |
| GTF2I | general transcription factor IIi |
| H1F0 | H1 histone family, member 0 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IPO8 | importin 8 |
| KIAA0355 | KIAA0355 |
| KLC2 | kinesin light chain 2 |
| KRT86 | keratin 86, type II |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC257152 | uncharacterized LOC257152 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MB | myoglobin |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MTMR11 | myotubularin related protein 11 |
| MVD | mevalonate (diphospho) decarboxylase |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLD3 | phospholipase D family, member 3 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROS1 | protein S (alpha) |
| RANBP17 | RAN binding protein 17 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF121 | ring finger protein 121 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH2D4A | SH2 domain containing 4A |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| SPATA7 | spermatogenesis associated 7 |
| SPIDR | scaffolding protein involved in DNA repair |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM254 | transmembrane protein 254 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TWF2 | twinfilin actin binding protein 2 |
| USP18 | ubiquitin specific peptidase 18 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WDR4 | WD repeat domain 4 |
| WDR91 | WD repeat domain 91 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF248 | zinc finger protein 248 |
| ZNF254 | zinc finger protein 254 |
