| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hexylcaine-5768 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ACACB | acetyl-CoA carboxylase beta |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADCK2 | aarF domain containing kinase 2 |
| ALPK1 | alpha-kinase 1 |
| ANXA10 | annexin A10 |
| APC | adenomatous polyposis coli |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| AURKC | aurora kinase C |
| BMP1 | bone morphogenetic protein 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CACFD1 | calcium channel flower domain containing 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAPN9 | calpain 9 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD4 | CD4 molecule |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CLEC1A | C-type lectin domain family 1, member A |
| COL6A1 | collagen, type VI, alpha 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DCN | decorin |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DIRAS2 | DIRAS family, GTP-binding RAS-like 2 |
| DOCK5 | dedicator of cytokinesis 5 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DRD2 | dopamine receptor D2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| ERGIC3 | ERGIC and golgi 3 |
| FAM46C | family with sequence similarity 46, member C |
| FAS | Fas cell surface death receptor |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLOT1 | flotillin 1 |
| FRY | furry homolog (Drosophila) |
| GPM6A | glycoprotein M6A |
| GPR17 | G protein-coupled receptor 17 |
| GPX3 | glutathione peroxidase 3 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HOMER3 | homer scaffolding protein 3 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXB7 | homeobox B7 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL11 | interleukin 11 |
| IL1R2 | interleukin 1 receptor, type II |
| IL1RN | interleukin 1 receptor antagonist |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KRT2 | keratin 2, type II |
| KRT34 | keratin 34, type I |
| KYNU | kynureninase |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LOC100127972 | uncharacterized LOC100127972 |
| MAOB | monoamine oxidase B |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MSC | musculin |
| MYF5 | myogenic factor 5 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLK4 | polo-like kinase 4 |
| PLXND1 | plexin D1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRR7 | proline rich 7 (synaptic) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| PVR | poliovirus receptor |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RASA3 | RAS p21 protein activator 3 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RGS3 | regulator of G-protein signaling 3 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SH3BP2 | SH3-domain binding protein 2 |
| SHOX2 | short stature homeobox 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| TEX15 | testis expressed 15 |
| TOP3B | topoisomerase (DNA) III beta |
| TP73-AS1 | TP73 antisense RNA 1 |
| TYMS | thymidylate synthetase |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VCL | vinculin |
| ZNF154 | zinc finger protein 154 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| AXIN1 | axin 1 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BFSP1 | beaded filament structural protein 1, filensin |
| BTC | betacellulin |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C1R | complement component 1, r subcomponent |
| C5 | complement component 5 |
| CCNJL | cyclin J-like |
| CCNO | cyclin O |
| CD82 | CD82 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CENPJ | centromere protein J |
| CFAP45 | cilia and flagella associated protein 45 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DENND4A | DENN/MADD domain containing 4A |
| DNAL4 | dynein, axonemal, light chain 4 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM204A | family with sequence similarity 204, member A |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GLB1L | galactosidase, beta 1-like |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPATCH3 | G patch domain containing 3 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H1D | histone cluster 1, H1d |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HMOX1 | heme oxygenase 1 |
| HOXC11 | homeobox C11 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL17RA | interleukin 17 receptor A |
| INO80D | INO80 complex subunit D |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KIFC1 | kinesin family member C1 |
| LIPG | lipase, endothelial |
| LOC257152 | uncharacterized LOC257152 |
| LRRC6 | leucine rich repeat containing 6 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MCC | mutated in colorectal cancers |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXRA8 | matrix-remodelling associated 8 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCDH17 | protocadherin 17 |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLXNA3 | plexin A3 |
| PRR14L | proline rich 14-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RUSC2 | RUN and SH3 domain containing 2 |
| RWDD2A | RWD domain containing 2A |
| SCARA3 | scavenger receptor class A, member 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM121 | transmembrane protein 121 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSC22D4 | TSC22 domain family, member 4 |
| TTC30A | tetratricopeptide repeat domain 30A |
| VWA1 | von Willebrand factor A domain containing 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF350 | zinc finger protein 350 |
| ZNF358 | zinc finger protein 358 |
| ZNF41 | zinc finger protein 41 |
| ZNF552 | zinc finger protein 552 |
| ZNF74 | zinc finger protein 74 |
| ZNF778 | zinc finger protein 778 |
