| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the hexylcaine-6244 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AOX1 | aldehyde oxidase 1 |
| APP | amyloid beta (A4) precursor protein |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| BMP4 | bone morphogenetic protein 4 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| BTD | biotinidase |
| CACTIN | cactin, spliceosome C complex subunit |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CBX7 | chromobox homolog 7 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CORO1B | coronin, actin binding protein, 1B |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FAM134B | family with sequence similarity 134, member B |
| FGFR2 | fibroblast growth factor receptor 2 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GLUL | glutamate-ammonia ligase |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPC1 | glypican 1 |
| H2AFX | H2A histone family, member X |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXC11 | homeobox C11 |
| IBSP | integrin-binding sialoprotein |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGL | immunoglobulin lambda locus |
| IL4R | interleukin 4 receptor |
| IL5RA | interleukin 5 receptor, alpha |
| KLC2 | kinesin light chain 2 |
| KLF9 | Kruppel-like factor 9 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINS | lines homolog (Drosophila) |
| LOC730101 | uncharacterized LOC730101 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MID1 | midline 1 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTMR1 | myotubularin related protein 1 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOTCH2 | notch 2 |
| OGFR | opioid growth factor receptor |
| OVOL1 | ovo-like zinc finger 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RASAL2 | RAS protein activator like 2 |
| RCAN1 | regulator of calcineurin 1 |
| RUNX1 | runt-related transcription factor 1 |
| S100A13 | S100 calcium binding protein A13 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPRR2B | small proline-rich protein 2B |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSR1 | signal sequence receptor, alpha |
| STX7 | syntaxin 7 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUGP2 | SURP and G patch domain containing 2 |
| TAT | tyrosine aminotransferase |
| TET3 | tet methylcytosine dioxygenase 3 |
| TEX261 | testis expressed 261 |
| TLE4 | transducin-like enhancer of split 4 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM222 | transmembrane protein 222 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPMT | thiopurine S-methyltransferase |
| TRAK1 | trafficking protein, kinesin binding 1 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VPRBP | Vpr (HIV-1) binding protein |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACTL8 | actin-like 8 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKRD28 | ankyrin repeat domain 28 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CA11 | carbonic anhydrase XI |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CAPN5 | calpain 5 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CENPC | centromere protein C |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNM1 | dynamin 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC5 | excision repair cross-complementation group 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM184A | family with sequence similarity 184, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FHOD1 | formin homology 2 domain containing 1 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H1E | histone cluster 1, H1e |
| IFT22 | intraflagellar transport 22 |
| IL15RA | interleukin 15 receptor, alpha |
| IL2 | interleukin 2 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA0895 | KIAA0895 |
| KIZ | kizuna centrosomal protein |
| LAMA3 | laminin, alpha 3 |
| LRRC49 | leucine rich repeat containing 49 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| LYRM9 | LYR motif containing 9 |
| MTMR11 | myotubularin related protein 11 |
| MYO1E | myosin IE |
| NDRG4 | NDRG family member 4 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDE12 | phosphodiesterase 12 |
| PGP | phosphoglycolate phosphatase |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRPH | peripherin |
| PRSS16 | protease, serine, 16 (thymus) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGS19 | regulator of G-protein signaling 19 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RWDD3 | RWD domain containing 3 |
| S100A4 | S100 calcium binding protein A4 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SECTM1 | secreted and transmembrane 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TFF2 | trefoil factor 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBXN6 | UBX domain protein 6 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFC | vascular endothelial growth factor C |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF473 | zinc finger protein 473 |
| ZNF571 | zinc finger protein 571 |
| ZNF586 | zinc finger protein 586 |
| ZNF668 | zinc finger protein 668 |
| ZNF767P | zinc finger family member 767, pseudogene |
