hic1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description hypermethylated in cancer 1|This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 3090)
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Genes

29 genes co-occuring with the biological term hic1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADRB2 adrenoceptor beta 2, surface
ARID1A AT rich interactive domain 1A (SWI-like)
BCL2L1 BCL2-like 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CTBP1 C-terminal binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAPK1 death-associated protein kinase 1
E2F1 E2F transcription factor 1
EPHA2 EPH receptor A2
FLNB filamin B, beta
HIC1 hypermethylated in cancer 1
HIC2 hypermethylated in cancer 2
KRAS Kirsten rat sarcoma viral oncogene homolog
LCN2 lipocalin 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MECOM MDS1 and EVI1 complex locus
MGMT O-6-methylguanine-DNA methyltransferase
MTA1 metastasis associated 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
SFRP2 secreted frizzled-related protein 2
SIRT1 sirtuin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TOB1 transducer of ERBB2, 1
TP53 tumor protein p53
VLDLR very low density lipoprotein receptor
ZNF189 zinc finger protein 189